Corynebacterium glutamicum B253: SB89_02375
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Entry
SB89_02375 CDS
T03668
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cgx
Corynebacterium glutamicum B253
Pathway
cgx00860
Porphyrin metabolism
cgx01100
Metabolic pathways
cgx01110
Biosynthesis of secondary metabolites
cgx01120
Microbial metabolism in diverse environments
cgx01240
Biosynthesis of cofactors
Module
cgx_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
cgx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SB89_02375
Enzymes [BR:
cgx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SB89_02375
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SB89_02375
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AJE66488
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Position
510475..512271
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AA seq
598 aa
AA seq
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MTIAHKPEMAETTGIETNQVSETIGVESLTHGNLRPVSSFEGQHGGQTEELLPGKVIFVG
AGPGNPDLLTVRAREVLGNAVRAITDEQVLSGVRAFVATEIPVPEDKLQAAEDEYERICI
EAKENGARRKPPRPAPPTAAEITEVSEATPAQIVELVQDALSYGGDVIRLVTGNPLSSDA
TLAEISAVSEAGLEFQVVPGMSLPATVPAFAGIALGSTYTETDVNGQDLDWDQLASAPQP
LVLQARVDDLSRIAQELKARNMSLETPVSVTANGTTRLQRTYDTTLGLLHKLDAELSGPL
VVTLGKGVDDRSKYSWWENRALYGWRVLVPRPREQAASMSARLSSHGAIPQEVPTISVEP
PRNPAQMERAIKGIVEGRYQWVVLTSVNAVKAVWEKITEFGLDSRSFAGVRIAAVGEKTA
AEIRSLGITPELLPARTRQNAQGLVDVFPEYFEELDPVGRVLLPRADIATDVLVDGLTHL
GWEVEDVVAYRTVRAAPPSADIRDMIKTGGFDAVAFTSSSTVKNLVGIAGKPHPRTIVAC
IGPMTAATAEELGLRVDVMPEIAEVPELIDALAEHVADLRAKGELPPPRKKRRRRKAS
NT seq
1797 nt
NT seq
+upstream
nt +downstream
nt
atgactatcgcccataagcccgagatggctgaaactaccgggatcgagaccaaccaggtt
tccgaaaccatcggggttgaatcgctcacgcacggaaacttacgtcctgtttcatctttt
gagggacagcatgggggacaaacggaagagttacttccaggcaaagtcatttttgttggg
gccgggcccggtaaccctgatcttcttacagttcgtgcccgtgaagttctgggcaacgcg
gttcgtgcgattactgatgaacaagtactaagcggcgttcgagcttttgtcgccactgaa
attcctgtgccggaagataagcttcaggctgcggaagatgagtacgagcgcatctgcatt
gaagcgaaggagaacggtgcacgccgtaagcctcctcgtccagcaccaccaaccgctgca
gagatcacggaagtttctgaggcgactccagctcagattgttgagcttgtgcaggatgct
ctttcttatggtggagatgttattcgtcttgtcaccggcaacccattgagcagcgatgcc
acactggctgagatctctgcagtttccgaggctggcctggagttccaggtggttccaggt
atgtctttgcctgcaacggttcctgcatttgcgggaatcgcgttgggctcgacctacacc
gaaactgatgttaacggtcaggatttggactgggatcagttggctagcgcacctcagcct
ttggtgctgcaggcccgcgtggatgacctttcccgtattgcacaggaactaaaggcccgc
aatatgtctttggaaactcctgtttctgtcaccgctaacggcaccacccgtttgcagcgc
acctatgacaccaccctcggtttgttgcacaagcttgatgctgaactgagcggacctttg
gttgttaccttgggcaagggcgtggatgatcgctccaagtactcatggtgggaaaaccgc
gctctgtacggttggcgtgtgctggtgcctcgccctcgggagcaagcggcatccatgtcc
gcacgtctgagcagccacggcgctatcccgcaggaagtccccacgatttcggtcgagcca
ccgcgcaacccagcgcaaatggaacgcgccatcaagggcatcgtcgaaggacgctaccag
tgggttgtcctcaccagcgtcaacgcagtgaaggcagtctgggagaaaatcaccgaattc
ggcctcgattcacgttccttcgcgggcgtccgcatcgccgcagtcggtgaaaaaaccgcc
gctgagatccgctcgctcggcatcacgccggagcttctgcctgcacgtaccaggcaaaat
gcgcaagggcttgtcgacgtgttccccgaatatttcgaagaactcgatccagtcggccgt
gtcctcttgccgcgcgcagatatcgcaaccgacgtgcttgtcgacggcctgacccacctt
ggttgggaagtcgaagacgtggtggcttaccgcaccgtccgcgcagcaccaccaagcgct
gacatccgcgacatgattaaaactggtggattcgatgccgtggccttcacctcttcatcg
accgtgaagaacctcgttggtattgcaggtaaaccacacccacgcaccatcgtcgcgtgc
atcggacccatgactgcagcgaccgctgaagaactgggactgcgcgttgatgtcatgcca
gagatcgccgaagtaccagaactgatcgacgctcttgcggaacacgtggcggatctgcgc
gctaagggcgagctgccgccgccgaggaagaaacgcaggcgtcgaaaagcgtcttaa
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