Caldicellulosiruptor hydrothermalis: Calhy_2163
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Entry
Calhy_2163 CDS
T01346
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
chd
Caldicellulosiruptor hydrothermalis
Pathway
chd00290
Valine, leucine and isoleucine biosynthesis
chd00620
Pyruvate metabolism
chd01100
Metabolic pathways
chd01110
Biosynthesis of secondary metabolites
chd01210
2-Oxocarboxylic acid metabolism
chd01230
Biosynthesis of amino acids
Module
chd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
chd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Calhy_2163
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Calhy_2163
Enzymes [BR:
chd01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Calhy_2163
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Ecm33
Motif
Other DBs
NCBI-ProteinID:
ADQ07871
UniProt:
E4Q7V3
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All DBs
Position
complement(2230361..2231941)
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AA seq
526 aa
AA seq
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MEDNKTIIIYDSTLRDGAQAGGISYTLEDKLKIVERLDKFGVKFIEAGNPGSNIKDQEFF
ARVKKMKLKNAKLIAFGSTRRVGIDVKDDPNIQSLIAADTEAVAIFGKSWDFHVKEVLKT
TEDENLQMIYDTIKYLKSLGKYVVFDAEHFFDGYKNNRKYALETLKVAKEAGADSLDLCD
TNGGTFPMDIYNITKEVVEMFPGTLIGIHCHNDTGMAVANSVMAVLAGARQVQGTINGYG
ERCGNADLITLIPNLQLKLGFKCIPDENIKHLTSLSRYVAEIANMIPNERAPYVGAYAFT
HKAGMHIDAVKKNPASFEHINPEIVGNTRRIVLSEVAGRATILDKIREIDPTVTKDSPVT
KEIIDELKRLENEGYQFESAEASFEMLIRKKLGLYQPFFTLKEFKVLINEPAVEYSSSAI
VKIAVDGVTAITAAEGDGPVHALDSALRKALEKFYPELKEVHLVDYKVRVLNAETATAAK
VRVLIESTDGKDTWTTVGVSTDIVNASWIALVDSLEYKLCKEKVGK
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
gtggaagataataagaccatcatcatttatgactcaaccttaagagacggtgctcaggct
ggtggaatttcatacactttggaagataagctcaagattgtagagagacttgacaaattt
ggtgtaaaattcatcgaggcagggaatcccggttctaacatcaaagaccaggagtttttc
gcaagagttaaaaagatgaaattgaaaaacgcaaagcttatcgcctttggttcaacaagg
cgagtgggaattgacgtgaaagatgaccctaacatccagtcattaattgcagctgacacc
gaagctgttgcaatctttggcaagtcgtgggattttcatgtcaaagaggtcttgaaaaca
acagaggacgaaaatcttcagatgatttatgatacaataaaatatttaaagtccttaggc
aagtatgttgtatttgacgcagagcacttttttgatgggtacaagaataacagaaaatac
gctttggagactttaaaggttgcaaaggaagcaggagcagattctttggacctgtgcgat
acaaacggtggcaccttcccaatggatatttacaacatcacaaaagaagttgttgagatg
tttcctgggacattgattggaattcactgtcacaacgacacaggcatggctgttgcaaac
tcggtcatggctgttttggcaggagctcgtcaggtacagggaactataaacggatatggt
gagaggtgtgggaacgcagaccttatcacgctcattccaaatcttcagctaaagcttggg
tttaagtgtatccctgatgagaatatcaagcaccttacatctctttcaaggtatgttgct
gagattgctaatatgattccaaacgagcgcgcaccatatgttggagcttatgcgtttact
cacaaggctggtatgcacattgacgctgtcaagaaaaatccagcttcgtttgagcatatt
aaccctgagattgttggaaacacaagaagaatagtactgtctgaggttgcaggaagggct
acaattcttgacaagattcgcgagattgacccgacagttacaaaagactcacctgtcaca
aaagagattattgatgagctaaagcgccttgaaaatgaaggatatcagtttgagtcggca
gaagcttcattcgagatgctaattagaaaaaaactgggactttaccagccgttctttact
ctcaaagaatttaaagttctcattaatgaaccggcagtagagtacagctcatctgcaatt
gtaaagattgcagtagatggggttacagcaatcactgctgcagaaggtgatggtcctgtt
catgctttagatagtgctttgagaaaggctttggaaaagttctatcccgaactaaaagag
gttcatcttgttgactataaagtacgggtactgaatgctgagactgcaactgctgcaaag
gtaagagttctgattgagtcaacagacggcaaagacacatggacaactgtaggtgtttca
accgacattgtaaatgcaagctggattgcacttgttgactcactggagtataagctttgc
aaagaaaaagtggggaaataa
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