Chromobacterium sp. ATCC 53434: CXB49_19685
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Entry
CXB49_19685 CDS
T05234
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
chro
Chromobacterium sp. ATCC 53434
Pathway
chro00300
Lysine biosynthesis
chro00550
Peptidoglycan biosynthesis
chro01100
Metabolic pathways
chro01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
chro00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CXB49_19685
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CXB49_19685
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CXB49_19685
Enzymes [BR:
chro01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CXB49_19685
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
TcdA_TcdB_pore
Motif
Other DBs
NCBI-ProteinID:
AUH52851
UniProt:
A0A2H5E0M8
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All DBs
Position
complement(4418774..4420135)
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AA seq
453 aa
AA seq
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MMTLSQAARLANGRLAGADGEVSRVITDSRLAQPGDLFVALKGERFDAHDFVAEVVAKGA
AALVRDGFELAGASLIQAGDDTRLALGRLAAGWRETQPAVRIGITGSNGKTTVKEMLAAI
LRAHAGADAVLATAGNFNNDIGLPLTLLQLKPQHRYAVIEMGMNHHGELSYLTGLTRPQV
ALVNNAMRAHFGHFGSTAEVARAKAEIFEGLSGDGVAVVNADDANLALFCAAAASHRQLS
FGLEQADVSVSDLALSALGSRFTLLSPAGEIEVSLPTPGEHNVRNALAAAAVALALDVPL
AAIAAGLAAFAGAKGRLQIKQSPRGLTVIDDSYNANPDSMKAGIDVLAGLPAPRCFVMGD
IGELGEGAPALHAEVGEHARARGIEQFFALGEVSRRAATAFGAAGQGFDSIDELLECLDS
RLASGTAVLVKGSRFMRMERVVEHLMQAKKEGV
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atgatgacgctgagccaagccgcccgcctcgccaacggccgcctcgccggcgccgacggc
gaagtgtcgcgggtgatcaccgacagccgcctggcgcagccgggcgatctgttcgtcgcg
ttgaagggcgagcgcttcgacgcccatgatttcgtcgccgaggtggtggccaagggcgcc
gccgcgctggtgcgcgacggcttcgaattggccggcgccagcctgatccaggcgggcgac
gacacccggctggcgctgggccgtctggccgccggctggcgcgagacgcagccggccgtc
cgcatcggcatcaccggctccaacggcaagaccacggtcaaggagatgctggcggcgata
ctgcgcgcccatgccggcgccgacgccgtgctggccaccgccggcaatttcaacaacgac
atcggcctgccgctgacgctgctgcagctgaaaccgcaacaccgctacgccgtgatcgaa
atgggcatgaaccaccacggcgagctcagctacctgaccgggctgacccggccgcaggtg
gcgctggtcaacaacgcgatgcgcgcccacttcggccatttcggctccaccgccgaggtg
gcccgcgccaaggccgagatcttcgagggactgagcggcgacggcgtggccgtcgtcaac
gccgacgacgccaatctggcgctgttctgcgccgcggccgcttcgcatcgccagctgagc
ttcggcctggagcaggccgatgtgagcgtgagcgatctggcgctgtcggcgctgggcagc
cgcttcacgctgctgtcgccggccggcgaaatcgaggtatcgctgccgacgccgggcgag
cacaacgttcgcaacgcgctggccgccgccgccgtcgcgctggcgctggacgtgccgctg
gccgccatcgccgcgggcctggccgctttcgccggcgccaagggccggctgcagatcaag
cagagtccgcgcggcctgacggtgatagacgacagctacaacgccaacccggactcgatg
aaggccggcatagacgtgctggccggcctgccggcgccgcgctgcttcgtgatgggcgat
atcggcgagttgggcgagggcgcgccggcgctgcacgccgaagtcggcgagcatgcgcgc
gcgcgcggcatcgagcagtttttcgcgctgggcgaggtttcgcgccgcgcggcgacggcc
ttcggcgccgccggacagggtttcgattcgattgacgagttgttggagtgcctggatagc
cggctggcttcgggtaccgccgttctggtcaagggctcgcgcttcatgcgcatggaacgg
gtggtggaacacctgatgcaagcaaagaaagaaggagtttaa
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