| Entry |
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| Symbol |
C3
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| Name |
(RefSeq) LOW QUALITY PROTEIN: complement C3
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| KO |
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| Organism |
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| Pathway |
| chx04080 | Neuroactive ligand-receptor interaction |
| chx04610 | Complement and coagulation cascades |
| chx04613 | Neutrophil extracellular trap formation |
| chx05150 | Staphylococcus aureus infection |
| chx05167 | Kaposi sarcoma-associated herpesvirus infection |
| chx05168 | Herpes simplex virus 1 infection |
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| Brite |
KEGG Orthology (KO) [BR:chx00001]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
100860826 (C3)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
100860826 (C3)
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
100860826 (C3)
04613 Neutrophil extracellular trap formation
100860826 (C3)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
100860826 (C3)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
100860826 (C3)
05168 Herpes simplex virus 1 infection
100860826 (C3)
05167 Kaposi sarcoma-associated herpesvirus infection
100860826 (C3)
09171 Infectious disease: bacterial
05133 Pertussis
100860826 (C3)
05134 Legionellosis
100860826 (C3)
05150 Staphylococcus aureus infection
100860826 (C3)
05152 Tuberculosis
100860826 (C3)
09174 Infectious disease: parasitic
05140 Leishmaniasis
100860826 (C3)
05142 Chagas disease
100860826 (C3)
09163 Immune disease
05322 Systemic lupus erythematosus
100860826 (C3)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100860826 (C3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:chx01002]
100860826 (C3)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:chx04131]
100860826 (C3)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:chx04147]
100860826 (C3)
Peptidases and inhibitors [BR:chx01002]
Peptidase inhibitors
Family I39: alpha2M family
100860826 (C3)
Membrane trafficking [BR:chx04131]
Endocytosis
Phagocytosis
Opsonins
100860826 (C3)
Exosome [BR:chx04147]
Exosomal proteins
Exosomal proteins of other cancer cells
100860826 (C3)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
7:complement(92699553..92735804)
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| AA seq |
1662 aa
MQPTSGPSLLLLLLLASLPMALGNPMYSMITPNILRLESEETVVLEAHGGQGNIQVSVTV
HDFPAKKQVLSNENTQLNSNNGYLSTVIIKIPASKELKSEKGHKFVIVVATFGNVQVEKV
VLISLQSGYLFIQTDKTIYTPGSSVLYRVFTVDHKLLPVGQTVFISIETPDGVLVKQDSL
SSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQVFSTEFEVKEYVLPSFEVQLEPEE
KFYYVDDPDGLKINIIARFLYGEQXDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEA
ILKRQVLLNGVQPSRADALVGKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKT
PKFFKPAMPFDLMVYVTNPDGSPARHIPVVTQGSNVQSLTQDDGVAKLSINTQNKRDPLT
ITVRTKKDNIPEGRQATRTMQALPYNTQGNSNNYLHLSVPRVELKPGETLNVNFHLRTDP
SQQAKIHYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLINAN
GQREVVADSVWVDVKDSCMGTLVVKNDGKEEKKHRPGKQITLKIEANHGSRVWLVAVDKG
VFVLNKKNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLTFKTSQGLETQQRSDPQ
CPKPAARRRRSVQLMEKRMDKVGQYSGDLRKCCEDGMRDNPMKFPCQRRAQFILQGDACV
KAFLDCCEYIARLRQQHSREGALELARSDLDDEIIPEEDIISRSQFPESWLWIIIDDFKQ
PDKNGISTKLTKVFLKDSITTWEILAVSLSDKKGICVADPYEITVMQDFFIDLRLPYSVV
RNEQVEIRAILYNYREAENLKVRVELLYNPAFCSLATAKKRHQQNIMIPARSSVAVPYVI
VPLKVGLHEVEVKAAVYNHFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEYLGQDGVQRE
EVPAADLSDRVPDTESETKILLQGTPVAEMAEDAIDGERLKHLIQTPSGCGEQNMIGMTP
TVIAVHYLDSTEQWEKFGVEKRQEALELIRKGYTQQLAFRQKSSAYAAFQNRPPSTWLTA
YVVKVFALSANLIAIDSRDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFKDAREKD
VSLTAFVLIALHEAKDICEAQVNSLGRSITKAGNFLENHYRELRRPYTVAIAAYALALLG
KLEDDRLTKFLNTAKEKNRWEEPNKKLYNVEATSYALLALLARKDFDTVPPVVRWLNEQR
YYGGGYGSTQATFMVFQALAQYQKDVPDHKELNLDVSIHLPSRNSLVKHRILWESASLLR
SEETKENEPFTVRAEGKGQGTLSVVTMYHAKLKGKVSCKKFDLRVSIHPTLEPVKKPQDA
KGSMILDICTKYLGDQDATMSILDISMMTGFSPDIDDLKLLSTGVDRYISKYEMNRDSNK
NTLIIYLDKVSHTQEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGM
LSKLCHKDTCHCAEENCFMHHTEEAITLEDRLDRACEPGVDYVYKTRLLQKKLEEDFDEY
IMVIEQIIKSGSDEVQVKQERKFISHIKCREALKLKEGAHYLVWGVSSDLWGDKPNISYI
IGKDTWVELWPEAEECQDEENQKQCEDLASFTENMVVFGCPN |
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| NT seq |
4989 nt +upstreamnt +downstreamnt
atgcagcccacctcaggtcccagcctgctgctgctgctgcttctagccagtctccccatg
gccttggggaaccccatgtattccatgatcacccccaacatcctgcgtctggagagcgag
gagactgtggtgctggaggcccacggaggacaagggaatattcaggtctcggtcactgtc
cacgacttcccggccaagaaacaagtgctgtcaaacgaaaacacccagctgaacagcaac
aatggctacctgagcaccgtcatcatcaagatcccggccagcaaagagttaaaatcagaa
aaggggcacaagttcgtgattgttgtcgcgaccttcgggaatgtccaggtggagaaggtg
gtgctgatcagccttcagagcgggtacctcttcatccagacggacaagaccatctacacc
ccaggctcctcggtcctctatcgggtcttcactgtggaccacaagctgctgcccgtgggc
cagacggttttcatcagcatcgagactcccgatggcgtccttgtcaagcaggactccctg
tcttctcacaaccagtttggcatcttggccttgtcctggaacattccagaactggtgaac
atgggggtgtggaagatcaaagcccactatgaagattctccgcagcaggtcttctccact
gagtttgaggtgaaggaatatgtgcttcccagttttgaggtccagctagagcctgaagag
aaattctactacgttgatgacccagatggcctgaagatcaacatcattgccaggttcttg
tacggggagcagntggacggaacagctttcgtcatctttggggtccaggatggtgaccgg
agaatttcattgactcactccctcacccgtgttccgatcaacgatggtaatggggaggcc
atactgaaacgtcaggttttgctgaatggagtacagccctcccgagctgatgccctggtg
ggcaagtccatatatgtgtccgccaccgtcatcttgcaatcaggcagcgacatggtggag
gcggagcgcactgggatccccattgtgacttccccctaccagatccatttcaccaagacc
cccaagttcttcaaacctgccatgcccttcgacctcatggtgtacgtgacgaaccctgac
ggctcccctgcccgccacatcccagtggtgacccagggcagcaatgtgcagtccttgacc
caggatgatggcgtggccaagctaagcatcaacacacagaacaaacgggatcccctgacc
atcaccgtacgcacaaagaaggacaatatccccgaggggcgacaggccaccaggaccatg
caggccctaccctacaacacgcaggggaactccaataactacctgcacctctctgtgccc
cgagtggagctcaagcctggggagactctcaacgtcaacttccacctgcgcacagacccc
agccagcaagccaagatccactactacacctacatgatcatgaacaaggggaagctgttg
aaggtgggacgccaggaccgagagcccggccaggacctggtggtgttgcccttgaccatc
acatcagacttcatcccttccttccgcctggtggcctattacacgctgatcaatgccaac
ggccagagggaggtggtggccgactccgtgtgggtggatgtcaaggactcgtgtatgggc
acgctggtggtgaaaaatgatgggaaggaagagaaaaagcatcgacccgggaaacagata
accctgaagatcgaggctaaccacgggtcccgagtgtggttggtggccgtggacaagggc
gtgtttgtgctgaataagaagaacaaattgacccagagtaagatctgggacgtggtggag
aaagcggacattggctgcaccccaggcagtggaagagactatgccggcgtcttcacggat
gcaggactcaccttcaagacaagccagggcctggagacccagcagaggtcagatccgcag
tgcccgaaaccagccgcccgccgacgccgctcggtgcagctcatggagaagaggatggat
aaagtgggtcagtacagcggcgatctgcgcaagtgctgcgaagacggcatgcgggacaac
cccatgaagttcccgtgccagcgccgggcccagttcatcctgcagggcgacgcgtgcgtc
aaggccttcctggactgctgcgagtacatcgctcggctgcggcagcagcacagccgcgag
ggcgccctggagctggcccggagtgacctggatgatgaaataatcccagaagaggacatc
atttcccgaagccaattccccgagagctggttgtggatcattattgacgactttaaacaa
ccagacaaaaatggaatctccacgaagctcacgaaagtgtttttgaaagactccatcacc
acttgggagattctggccgtgagcttgtcggacaagaaagggatctgtgtggctgacccc
tatgagatcactgtgatgcaggatttctttattgacctgcgtctcccctactcggtggtg
cgcaatgagcaagtggagatccgagcgatcctctacaactaccgggaggccgaaaatctc
aaggtgagggtggaattgctctacaatccagccttctgtagcctggccactgccaagaaa
cgccatcagcagaatataatgatcccagccaggtcctcagtggcggtaccttacgtcatt
gtgcccctgaaggtcggcctccatgaggtggaggtcaaggctgccgtctacaatcacttc
atcagtgatggtgtcaagaagaccctgaaggtcgtgccagaaggaataagagtcaacaaa
actgtggccattcgcacactgaatccagaatatctgggtcaagatggggtgcagcgagag
gaagtcccagctgcagatcttagtgatcgagtcccagacaccgagtcagagaccaagatc
ctcctgcaagggactccggtggccgaaatggcagaggacgccatcgacggagagcggctg
aagcaccttattcaaaccccctcgggctgtggggagcagaacatgattggtatgacgccc
acggtcatcgccgtgcactacctggacagcactgagcagtgggagaagttcggcgtggag
aagcgccaggaggccctggagctcatcagaaaggggtacacccagcagctggctttcaga
caaaaaagctcagcctacgccgccttccaaaatcggccccccagcacctggctgactgcc
tacgtggtcaaggtctttgcactgtccgccaacctcatcgccatagactccagggacctc
tgtgagaccgtcaaatggctgatcctggagaagcagaagcctgatggaatcttccaggag
gatgggcccgtgatacaccaagaaatgattggtggcttcaaggacgccagggagaaagat
gtgtcccttacagcctttgttctcatcgcgctgcacgaggctaaagacatttgcgaggca
caggtcaacagcctgggccgcagcatcactaaggcaggaaacttccttgaaaaccactac
agagagctgcgaagaccatatactgtggccattgctgcctatgccctggctttgttgggc
aagctggaggatgaccgcctcaccaaatttctgaatacagccaaagaaaaaaaccgctgg
gaggaacccaacaagaagctctacaatgtggaggccacgtcttacgccctcttggctctg
ctggcacgcaaagacttcgacactgtgcctcctgtcgtgcgctggctcaacgagcagaga
tactatggaggtggttatggctccacgcaggccactttcatggtgttccaagccctggcc
caataccagaaggatgttcctgatcacaaggagctgaacctggatgtgtccatccacctg
cccagccgcaattctttggtcaagcatcgtatcctctgggaatctgccagcctcttgcgc
tcagaagagactaaggaaaatgagcctttcacagtaagagctgaagggaaaggacaaggc
accttgtcggtagtgaccatgtaccatgccaagctcaaaggcaaagtctcctgcaaaaag
ttcgacctccgggtttccatacacccaaccctcgaaccagtcaagaagcctcaggacgcc
aaaggttccatgatccttgacatctgtaccaagtacctgggagaccaggatgccactatg
tccatccttgatatatccatgatgacaggcttctcacctgatattgatgacctgaaactg
ctgagcactggtgtcgacagatacatctctaagtatgagatgaacagagactccaacaag
aacacactcatcatctacctggacaaggtctcacacacacaggaggactgtctgtccttc
aaagttcaccagtactttaatgtcggacttatacagcctggggcagtcaaggtgtactcc
tattacaacctggatgaaacttgtatccgcttctatcacccggataaagaggacggaatg
ctgagcaaactctgccacaaagatacctgccactgtgcagaggagaactgcttcatgcac
cacacggaggaggcgatcactctggaggaccggctggacagggcctgcgagccgggcgtg
gactatgtatacaagaccagactcctccagaagaagcttgaagaggactttgacgagtac
atcatggtgatcgagcaaatcatcaaatcgggctctgacgaggtgcaggtgaaacaggag
cgcaagttcatcagccacatcaagtgcagggaagcccttaaactgaaggagggggcacac
tacctcgtgtggggcgtgtcctctgacctgtggggcgacaaacccaacatcagctacatc
atcggaaaggacacctgggtggagctgtggcccgaagctgaagaatgtcaagatgaggag
aaccagaaacagtgcgaggacctggccagcttcacggagaacatggttgtctttggctgc
cccaactga |
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