Capra hircus (goat): 100860943 Help Entry 100860943         CDS       T02910                                  Symbol TSC2 Name (RefSeq) tuberin   KO K07207   tuberous sclerosis 2 Organism chx  Capra hircus (goat) Pathway chx04072   Phospholipase D signaling pathway chx04115   p53 signaling pathway chx04140   Autophagy - animal chx04150   mTOR signaling pathway chx04151   PI3K-Akt signaling pathway chx04152   AMPK signaling pathway chx04211   Longevity regulating pathway chx04218   Cellular senescence chx04714   Thermogenesis chx04910   Insulin signaling pathway chx04919   Thyroid hormone signaling pathway chx05163   Human cytomegalovirus infection chx05165   Human papillomavirus infection chx05168   Herpes simplex virus 1 infection chx05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:chx00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     100860943 (TSC2)    04151 PI3K-Akt signaling pathway     100860943 (TSC2)    04152 AMPK signaling pathway     100860943 (TSC2)    04150 mTOR signaling pathway     100860943 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100860943 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     100860943 (TSC2)    04218 Cellular senescence     100860943 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100860943 (TSC2)    04919 Thyroid hormone signaling pathway     100860943 (TSC2)   09149 Aging    04211 Longevity regulating pathway     100860943 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     100860943 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     100860943 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     100860943 (TSC2)    05163 Human cytomegalovirus infection     100860943 (TSC2)    05165 Human papillomavirus infection     100860943 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:chx01009]     100860943 (TSC2) Protein phosphatases and associated proteins [BR:chx01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      100860943 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  100860943 NCBI-ProteinID:  NP_001272482 UniProt:  F2XXG1 LinkDB All DBs Position 25:1504585..1535313 Genome browser AA seq 1727 aa AA seqDB search MAKPASKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVARTKKFEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGILR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMVCLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIHHMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAVTCPNEVVSYEIVLSITRLIKKYRRDLQAVTWDI LLNIIERLLQQLQSLDSPELSAIVHDLLSTVEELCDQNEFHGSQERYFELVERCADQRPE SSVLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDRDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVIARSLS PPPELEERDVAAHSASLEDVKTAVLGLLVILQTKLYALPASHATRVYETLVSHIQLHYKH SYTLPIASSIRLQAFDFLLQLRADSLHRLGLPSKDGLVRFSPYCVCDYPGPAPAGPAVRL GSLPYSLLFRVLLQCLKQETDWKVLKLMLSKLPESLRYKVLIFTSPCSVDQLSAALCSML SGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYLDKTRQREVVYCLEQGLIHRCA GQCVVALAVCSVEMPAVVLKALPVLVVKLTHISATASMAIPLLEFLSTLARLPHLYRNFA AEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVL LSFDDTPEKDSFRARSTSLNERPKRIQTSLTSASLGSADENSMAQADDNLKNLHLELTET CLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDS GELQGGPELSSDPSVHVRQTKEAPAKLESQAGQQVYHGARDRVRSMSGGHGLRVGALDAP ACHFPGSPTSLGSQTAPAGQPEKASAGSPLPAQKEKTNLAAYVPLLTQGWAEILVRRPTG NTSWLMSLENPLSPFSSDINSMPLQELSNALMAAERFKERRDTALYKSLSVPAAGSAKPS PPPRCNTDSAVVLEEGGPGEASLSAEPPELEDFEATLGSDGHCGRSDAFSRSSSTSSQEE KSFHAEELPPGGIPIERAVSSEGSRASVDLAFQPSQPLSKSSSSPELQTLQDILGDPGDK AEVGRLSPEAKARSQSGILDGEGAPWSAPGEERRGRGPTQPEGPLPSSCPRSPSGLRPRG YTISDSAPSRRGKRVERDAFKSRAGTSNTEKVPGINPSFVFLQLYHSPFFGDESNKPILL PNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGKLI ELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLG NDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECNLVSLQCRKDMEGLVDTSMAKI VSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRIREEAHYSS ASLPLMQTHPPGHAKAPAQAPAESTPAYETGQRKRLVSSVDDFTEFV NT seq 5184 nt NT seq  +upstreamnt  +downstreamnt atggctaagccagcaagcaaagattcaggcttgaaggagaagttcaagattctgttggga ctggggactccacggccaaaccccaggtctgcagagggcaagcagactgagtttatcatc accgcggaaatcctgagagagctgagtgttgaatgtggcctcaataatcgcatccgggtg atagggcagatctgtgaggttgccagaacgaagaaattcgaagagcacgcggtggaagca ctctggaaggccgtctcggacctgctgcagccagagcggccacccgaggcccggcatgcg gtgctggctctgttgaaggccattgtgcagggacagggggaccgcctgggcattctcagg gccctcttcttcaaggtcatcaaggattacccctctaatgaagacctccacgaaagactg gaagttttcaaggccctcacagacaatgggagacacatcacctacttggaagaagagctg gcggactttgtcctgcagtggatggacgttggcctgtcctccgaattcctcctggtgctc gtgaacttagtcaaattcaacagctgttaccttgatgaatacatcgcctccatggtccac atggtctgcctgctctgtgtccagaccgtgtcctccgtggacatagaggtgtctctgcag gtgctggatgctgtggtttgctacaactgtctgccagccgagagcctccccctgttcatc gtcaccctctgccgcaccatcaacgtcaaggagctctgtgaaccttgctggaagctgatg cgcaacctcctgggcacccacctgggccacagcgccatccaccacatgtgccgtatcatg gaagacagagcctacatggaggacgcaccgctgctgagaggagctgtgttctttgttggc atggctctctggggtgcccaccggctctattctctcaagaactccccaacatctgtgttg ccatcgttttatgaggccgtgacctgtccgaatgaggtggtgtcctatgagattgtcctc tccataaccagacttatcaagaagtacaggagggacctccaggccgtgacctgggacatc ctgctgaacatcatcgagcgcctgctccagcagctccagagcctggacagtccagagctg agcgccatcgtgcacgacctgctgagcacagtggaggagctgtgcgaccagaacgagttt cacggctcgcaggagagatactttgagctcgtggagaggtgtgcggaccagaggcctgag tcgtccgtcttaaacttaataacctacagggctcagtccatccatccagcgaaggacggc tggatccacaacctgcagctgctgatggagaggttcttcaggaacgagtcacgtagcgct gtgcgcatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacaggcagttctat gaggaagagcttatcaactcagtggtcatctcgcagctctcccacatccctgaggataga gaccaccaggtccggaagctggccactcagctgctggtagatctggccgaaggctgccac acccaccacttcaacagcctactggacatcattgagaaagtgatcgcccgctccctctct ccgccccctgagctggaggagagagatgtggccgcgcactcagcctccttggaggatgtg aagactgcggtcctggggctcctggtcatccttcagaccaagctgtatgccctgcccgcc agccatgccacacgtgtgtatgagacgctggtcagccacattcagctccactacaagcac agctacaccctgcccattgccagcagcatccgtctgcaggccttcgacttcctgctgcag ctgcgggccgactcactgcaccgcctgggcctgcccagcaaagatgggctcgtgaggttc agcccctactgcgtctgtgactaccctggccccgcacccgcgggccctgccgtgcgcctc ggctccctgccctactccctgctcttccgtgttctgctgcagtgtctgaagcaggagacc gactggaaggtgctgaagctgatgctcagcaagctgcccgagtcgctgcgctataaggtc ctcatcttcacctccccgtgcagcgtcgaccagctgtccgccgccctctgctccatgctt tcaggtcccaagaccctggagcggctccgaggcaccccagaaggcttctccagaaccgac ctgcatcttgctgtggttcccgtgctgacagccctgatctcttatcataactacttggac aaaactagacagcgggaggtggtgtactgcctggagcagggcctcatccaccgctgtgcc ggccagtgtgtggtggcgctggccgtgtgcagcgtggagatgcctgccgtcgtcctcaag gcgctgcctgtcctggtcgtgaagctcacgcacatctcggccacggccagcatggccatc ccgctcctcgagttcctgtccactctggccaggctgcctcacctctacaggaacttcgca gcagagcagtatgccagcgtgtttgccatctccctgccgtataccaacccctccaagttc aatcagtatatcgtgtgcctggcccatcacgtcatagccatgtggttcatcaggtgccgc ctgcccttccggaaggactttgttccttacatcaccaagggtctgcgctccaacgtcctc ctgtcttttgatgacactcccgagaaggacagcttcagagcgcggagcaccagtctcaac gagaggcccaagaggatccagacctctctcacgagcgccagcttggggtctgcagatgag aactcgatggcccaggccgacgacaacttgaaaaacctccacctggagctcacagagacg tgtctggacatgatggccagatacgtgttctccaatttcacggcagtccccaagaggtcc cctgtaggagagttccttctggctggtggcaggaccaaaacctggctggttgggaacaag cttgtcaccgtgacgacgagcgtggggaccgggacccggtcactgctaggcctggactcg ggagagctccagggcggcccggagttgagctctgaccccagcgtgcacgtgagacagaca aaggaggcacccgccaagctggagtcccaagctgggcagcaggtgtaccacggagcccgg gaccgggtccgttccatgtccgggggccatggccttcgtgtgggtgccttggacgctcca gcctgccacttccctggcagccccacatccctgggctcccagactgctccagccggccag cctgagaaggcctcagctggcagcccgctcccagcgcagaaagagaagacaaacttggcc gcttacgtgcccctgctgacccagggctgggcggagatcctggtccgcaggcccacaggg aacaccagctggctgatgagcctggagaacccgctcagccccttctcctcggacatcaac agcatgccgctgcaggagctgtccaatgccctcatggctgccgagcgcttcaaggaacgc cgcgacacagccctgtacaagtcgctgtcagtgccggcggccggctcggccaagccatcc ccgcccccacgctgcaacacagattccgcggtagtcctggaggagggaggtccaggcgag gccagtttgtctgcagagcctcccgagttggaagacttcgaggcaacactgggctccgat gggcactgtgggcgcagcgacgctttcagcaggtcatcttccacctccagccaggaggag aagtcattccacgccgaggagttgcctcctgggggcatccccatcgagcgggcggtctcc tcggagggctcccgggcctccgtggacctcgccttccagccctctcagcccctgagcaag tccagctcgtcgcctgagctgcagaccctgcaggacatcctgggggaccccggggacaag gctgaggttggccggctgagccctgaggccaaggctcggtcgcagtcagggatcctggac ggggaaggtgctccctggtcagccccgggtgaggaacgccggggccggggccccacccag ccagagggccccctgccttccagctgtccccgctcccccagtgggctgcggccccgaggc tacaccatctcggattcggccccgtcacgcaggggcaagagggtggagagggatgccttc aagagccgggcagggacctccaacaccgagaaggtgccaggcatcaaccccagcttcgtg ttcctgcagctctaccactcgccgttcttcggtgacgagtccaacaagccaatccttttg cctaatgagtctttcgaacggtcagtgcagctccttgaccagatcccgtcatacgacacg cacaagatcgcagtcctgtacgtgggagaaggccagagcaacagcgagctcgccatcctg tccaatgagcacggctcctacaggtacacagagttcctcacagggctgggcaagctcatc gagctcaaggactgccagccggacaaggtgtacctgggcggcctggacgtgtgcggcgag gacggccagttcacctactgctggcatgacgacatcatgcaagcggtcttccacatcgcc accctgatgcccaccaaggacgtggacaagcaccgctgtgacaagaagcgccacctgggc aacgacttcgtgtccattgtctacaatgactctggcgaggatttcaagttgggcaccatc aagggccagttcaactttgtccacgtgattatcacacccctggattacgagtgcaacctg gtgtctctgcagtgcaggaaagacatggagggccttgtggacaccagcatggccaagatc gtgtccgaccgaaacctgcccttcgtggcccgccagatggccctgcatgcaaacatggcc tcgcaggtgcaccatagccgctccaaccccaccgacatctacccctccaagtggatcgcc aggctccgccacatcaagcggctgcgccagcggatccgtgaggaagcccactactcaagc gccagcctgcccttgatgcagacacaccctcctggtcatgccaaggctccggcacaggcc ccagccgagtccacgcctgcctatgagacgggccagcggaagcgcctggtctcctctgtg gacgatttcactgagttcgtgtga

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