Capra hircus (goat): 102172194
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Entry
102172194 CDS
T02910
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
chx
Capra hircus (goat)
Pathway
chx00230
Purine metabolism
chx00670
One carbon pool by folate
chx01100
Metabolic pathways
chx01523
Antifolate resistance
Module
chx_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102172194 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102172194 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102172194 (GART)
Enzymes [BR:
chx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
102172194 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
102172194 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
102172194 (GART)
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SSDB
Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_4
RimK
Motif
Other DBs
NCBI-GeneID:
102172194
NCBI-ProteinID:
XP_005674728
UniProt:
A0A452F8K0
LinkDB
All DBs
Position
1:411672..440873
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGNGGREHTLAWKLAQSTHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLNSVGVRCFGPTAEAAQLESSKRFAKEFMDRHGIS
TARWKAFTKPEKACDFIMSADFPALVVKASGLAAGKGVIIAKSKEEACDAVREIMQGKAF
GEAGETVVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVSKDLLLKIKNTILQRTVDGMQEEGMPYTGVLYAGIMLTKNGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNCAAVTVVMASKGYPGDYTKGVEITGFPEA
RALGLEVFQAGTALKDGKVVTNGGRILTVTAIRENLISALEEARKGLAAIKFEGAVYRKD
IGFRAIAFLQQTRGLTYKESGVDIVAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFTDPLLACGTDGVGTKLKIAQQCGKHETIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLHTTEAVIAGIAQACRKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDAVIGIASSGLHSNGFSLVRKIVANSSLQYSSPAPVGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGRVKAVAHITGGGLLENIPRVLPQKLGVNLDAQTWRVPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSEDLVKQTLQDIEQHQEEAWVIGRVVACPEGSPRVKVEH
LIETMQINGSVLENGTLRNHISVQPKKARVAVLISGTGSNLQALIDSTREPGSLAHIVVV
ISNKAAVAGLDKAEKAGIPTRVINHKLYKNRAAFDNAVDKVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVETLSERVKLAEHKIFPSALQLVASGAVCLGENGRICWVTED
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtcattggcaatggaggacgggaacacacgctggcctggaaa
cttgcacagtctactcatgtcaaacaagtgttggttaccccaggaaatgcaggcactgcc
tgctctgagaagatttcaaatactgacatctcaatcagtgatcatactgcccttgcgcag
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctagctgct
ggaattgttgggaacctgaactctgtgggagttcggtgctttggccctacagcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacatggaatctca
acagcaagatggaaagctttcactaaacctgaaaaagcctgtgacttcattatgagtgca
gacttccccgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtaattatt
gccaagagcaaagaggaggcctgtgacgctgtcagagagattatgcagggtaaagcattc
ggagaagcaggagaaacagttgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggacggactgtggcgcccatgcccccagcacaggaccataagcga
ttgctggagggtgatcagggccccaacacggggggaatgggagcctactgtccagcccct
caggtttctaaggatttgttgctaaaaattaaaaataccattcttcagaggacagtggat
ggcatgcaggaggagggtatgccatacacaggtgtcctctatgctggtataatgctgacg
aagaatggccccaaagttctggaatttaattgccgtttcggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttagatggcttg
ctctgcacatctctgcctgtttggctggacaactgtgctgccgtaactgtggtcatggca
agtaaaggttacccaggagactacaccaagggtgtagagataacagggtttcctgaggct
cgggctttaggactggaggtgttccaagcaggcactgccctaaaagatggcaaggtggtg
actaacgggggtaggatccttactgtcacggccatcagggaaaatctcatctcagccctt
gaagaagccaggaaaggacttgctgctataaagtttgagggagctgtttatagaaaagac
attggctttcgagccatagctttcctccagcagaccaggggcctgacttacaaggaatct
ggggtagacattgtagctggtaatatgctggtccagaaaattaaacctttagcgaaggcc
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcactgatcctcttctggcctgtggaacagatggcgttgggacaaaactg
aagattgcccagcagtgcggtaaacatgagaccattggtcaggatttggttgcgatgtgt
gtaaatgacattctggcccaaggagcagagcccctctttttccttgattacttttcctgt
ggaaaacttgacctccatacgactgaagctgttatcgctgggatcgcccaagcttgtaga
aaggctggatgtgctctcctcggaggtgaaacggcagagatgcctgacatgtaccctcct
ggagagtatgatctagctggttttgccgttggcgccatggagcgggatcagaaacttcct
cacctggaaagaatcacagaaggggacgctgttattggaatcgcttcatctggtcttcac
agcaacggattcagccttgtgaggaaaatagtagcaaattcttccctccagtactcttct
ccagcacctgttggttgtggtgaccagaccttaggtgacttgcttctaaccccaaccaga
atctacagccactcactgttacctgtcctgcgttcaggacgtgttaaggctgttgcacat
attactggtggaggattactggaaaacatccccagagtcctccctcagaaattgggggtg
aatttagatgcccagacctggagggtccccaggatcttctcatggttacagcaggaaggc
cacctctctgaagaggagatggccagaacatttaactgtgggattggggctgccctcgtg
gtgtcagaggacctggtgaagcagactctgcaggatattgagcagcaccaggaagaagcc
tgggtgattggcagagtggttgcgtgtcccgaaggttctcctcgtgtgaaagtcgagcat
ctgattgaaaccatgcaaataaatggatcagtactggagaatggaaccctgagaaatcat
atctctgttcaaccgaaaaaggcaagagtagctgtcttaatatctgggacaggatcgaac
ctccaagctctcatagacagcactagggagccaggtagcttggcacacattgtcgttgtg
atctccaacaaagctgcagtggctggcttagataaagcagaaaaagccgggattcccacc
agagtaattaaccataaattatataaaaatcgtgcagcatttgacaatgcggttgacaaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttgtct
ggcccctttgtcagaaaatggaatgggaaaatgctcaatatccacccatccttgctccct
tcgtttaagggttcaaatgcccatgaacaagtcctggacgctggggtcacagtcaccggg
tgcaccgtgcactttgtagctgaagatgtagatgctggtcaaattatcttacaggaagcc
gttccagtgaagaggggtgacactgttgaaactctatctgagagagtaaaattagcagaa
cataaaatatttccctcagccctccagctggtagccagtggagctgtatgtcttggagaa
aatggcagaatctgttgggtcacagaggactga
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