Capra hircus (goat): 102175061
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Entry
102175061 CDS
T02910
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X3
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
chx
Capra hircus (goat)
Pathway
chx00230
Purine metabolism
chx01100
Metabolic pathways
chx04927
Cortisol synthesis and secretion
chx04934
Cushing syndrome
chx05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102175061 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
102175061 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
102175061 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102175061 (PDE8A)
Enzymes [BR:
chx01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
102175061 (PDE8A)
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GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_3
PAS_4
DUF5894
SPO22
PAS_12
PAS_8
Motif
Other DBs
NCBI-GeneID:
102175061
NCBI-ProteinID:
XP_013828426
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Position
21:21946778..22090137
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AA seq
753 aa
AA seq
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MRFHPDQLQVLLVFTKEDNQCNGFCRACEKAGFMCTVTKEAQTALACFLDKHHDIIIIDH
RNSRHLDAEALCRSIRSSKLSENTVIIGVVRRVDREESCVMSLIAAGFTRRYIENPSPMA
CYNELLQLEFGEVRSQLKLRACNSMFAALEKSQEAIEITSEDHIIQYANPAFETTMGYQS
GELIGKEIAEVPINEKKADLLDTINSCKEWQGIYSVRKKNGDNVQQNVKIIPVIGQGGKI
RHYVSIIRVCNGNNKAEKVAECVQTDSYADNQSGKHKDRRKSSLDVKTVASRTNEVSSQR
RHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLEILRTTELYSPQFGAKD
DDPHANDLVGGLVSDGLRRLSGNEYVLSTKNLQQAASSSIVPISLHDVPSQITRAMEKEE
YWDFNIFELEAATHKRPLIYLGLKVFARFGVCEFLKCPEATLRSWLQVIEANYHASNPYH
NSTHSADVLHATAYFLCKERIKQTLDPLDEVSALIAATIHDVDHPGRTNSFLCNAGSELA
ILYNDMAVLEHHHAALAFQLTTGDAKCNIFKNMERSDYQTLRQGIIDMVLATEMTKHFEH
VNKFVNIINKPLVALEEDEETDKDQEAINTMLRTPENRTLIKRMLIKCADVSNPCRPLEQ
CIEWAARISEEYFSQTDEEKQRDLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAF
VDLPELMQHLDNNFKYWKGLDDMKLRSLRPPPE
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atgagatttcatccagatcaactccaggtacttttagtgtttaccaaagaagataaccag
tgtaatggattctgcagggcgtgtgaaaaagcagggtttatgtgtacagttaccaaggag
gctcagactgccctcgcctgtttcttggacaaacaccatgacatcatcattatagaccac
agaaattcccgacatctggatgctgaggcgctgtgcaggtctatcagatcatcaaaactc
tcagaaaacacagttattattggtgtagtacgcagagtggatagagaagagtcatgtgtg
atgtccctcattgctgctggcttcacaaggaggtatatagaaaaccccagccccatggcc
tgttacaatgaactgctccagctggaatttggagaggtgcgctcacagctgaaactcagg
gcttgtaattcaatgttcgctgcattagagaaaagtcaagaagcaattgaaattacaagt
gaagaccacattatccagtatgcaaatccagcgttcgaaacaacaatgggctatcagtca
ggtgaattaatagggaaggagatagcagaagtgcctataaatgaaaaaaaggctgatttg
ctcgatactataaattcatgcaaggaatggcaaggaatttactctgtcaggaagaaaaat
ggagataacgtacaacaaaatgtgaagataatacctgtcattggacagggaggaaaaatt
agacactatgtgtccattatcagagtgtgcaatggcaacaataaggcggagaaggtagct
gagtgtgttcagaccgacagttatgcagataatcagtcaggcaaacataaagacaggaga
aaaagctccctagatgtcaaaactgttgcctctcgaacaaatgaagtttccagccagaga
cgacactcttcaatggcccggatccattccatgacgatcgaggcgcccatcaccaaggtc
atcaatatcatcaatgctgcccaggaaagcagtcccatgcctgtgacagaagccttagac
cgagtgctggaaattctaagaaccactgagttatattcgccacagttcggtgctaaggac
gatgatcctcatgccaacgacctcgttgggggcctggtgtctgatggtttgcgaagatta
tccggaaatgagtatgttctttcaacaaaaaaccttcagcaggctgccagcagcagcatc
gtccccatctcccttcatgatgtcccgtcacagataactcgggccatggaaaaggaggag
tactgggacttcaatatttttgaattggaggctgccactcataaaaggcctttgatttac
cttggtctcaaagtgtttgctcgcttcggagtctgtgaattcttaaaatgccccgaggcg
acgctgagatcctggttacaggtgatcgaagccaattaccacgcttccaacccctaccac
aactccacgcactctgctgatgtgctgcacgctactgcctactttctgtgcaaagagagg
atcaagcaaactttagacccacttgatgaagtcagtgccctcatcgcagccactatccac
gatgtggaccaccctgggaggaccaactccttcctgtgcaatgccgggagcgagctggcc
attctctacaacgacatggctgtgctggagcaccaccatgcggccttggctttccagctg
accactggcgatgccaaatgcaacatctttaaaaacatggaacggagcgactaccagacg
ctgcgccagggtatcatcgacatggtgttagccacagaaatgacaaagcactttgagcac
gtcaacaaatttgtcaacatcatcaacaagcccttggtagcattagaagaagatgaggaa
actgataaagatcaagaagccataaacaccatgctcaggactccagagaaccggactctg
atcaaaaggatgctgatcaagtgtgctgacgtgtccaacccctgccggcccctggagcag
tgcatcgagtgggctgcacgcatctcagaagagtatttctctcagacagacgaagagaag
caacgggacttgcctgtggtgatgccggtttttgacagaaatacctgcagcatccccaaa
tcccagatctctttcatcgactacttcatcacagacatgtttgatgcctgggacgccttt
gtagacctgcccgagttaatgcagcatctcgacaacaactttaaatactggaaaggactg
gacgacatgaagctgcggagcctgcgcccgcctcccgaatag
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