Capra hircus (goat): 102177068
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Entry
102177068 CDS
T02910
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
chx
Capra hircus (goat)
Pathway
chx05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
102177068 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
chx03021
]
102177068 (SETX)
Enzymes [BR:
chx01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
102177068 (SETX)
5.6.2.5 RNA 5'-3' helicase
102177068 (SETX)
Transcription machinery [BR:
chx03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
102177068 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
Helicase_RecD
nSTAND3
SLFN-g3_helicase
TniB
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
102177068
NCBI-ProteinID:
XP_017911523
UniProt:
A0A452FF91
LinkDB
All DBs
Position
11:complement(101796599..101881538)
Genome browser
AA seq
2659 aa
AA seq
DB search
MSTCCWCTPGGTSTTDFLQRYASKTRSSEFQTADEDLCYCLECVAEYHKARDELPFLHEV
LWELETLRLINHFERSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHEHVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLENPDIYTSSVLEKGKLVLLPSHMYDTANYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSNDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSCMRTKLEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFRDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKFKVP
QFSTSVDLNPACKTPPASFKEESEQIGKKSEKDVYCLENSSPTSSKEPMKADAYQVQESI
LSKANNAIEESKEPCYIKDLKLEGHLSAESCLKLSSKNLACERVQNQVKISTGKYKSVKE
NSSCTPQDGTLRNGPEKVFDRGIIISRRLLTVSSTDSMEKVSASNEDFSLKDDDLGKSST
AKSKTHKDGVCAKLSHVIKKQHRKSISLEENLAVSSIEGFYSEKDIGGQKGGGNICTPSL
VPNGILDDKNGEQKSQSCLLLRKKEVKKEKLDIFSTPENSCQIQECHVDTKDLVSLTEMT
NTFMTKASPFKEPVTGHELRDRKISRSTDQFSSNLREQDLSSSPQPDTLTDSQVDRDLHK
LSLMAQASVTKFPSDSTQKSLSQIQRKVKDEKRCFTANQNIRETCHGQVIIISDSDEEEE
EERILGLKEQMKEIKACIEKECPEQHTSIANTNVEQKVLIKEENPMSLLQFEESDSQFFE
FETPCEVFSVWHDQKPDKNSAQENEKNPCSTPVGDTANDLGYETDYVSEEVIKKVAENFE
ERTKPRSSSTSVEEFCEIEVKKPKRRRYEKPIAEDPLRPSSSVKNEDQSNKGNLSKNDFK
GVDPRATVPSSSVQRNAAVSPKKSLPKPRTYSRPVRKVPVVKASKKSPSDTKKGQSKSSH
YISCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKAPRRAFELSQRSLECIDQLRDHGRSVG
VVDTRKKTKLISPQTLSVRNNKKLLTSQDLQLHRQMRSKSQHNRQGRFDCRSTDKTRAGP
CAAQSSAVPESSKSDYSHHGGAEVTANNKGKQLLTCQSSETEPVKANQCNPVMVNGRTAT
TEAIVPTSEALLGRGDPTVHHLEVATLKEGEPEFSSDIEEEDIFLTQRDPEDMDLCSQIE
GEYDKLIEVIDGKDTVQGEEECVRQPQLESLSSTKCRYKDCVETLKNPGEYCSKHSKTKA
TDEDTFRKPGLPLSASKRSRPSTTKVFSSSSTSRIAGLSKSLESTASLPSCLKNKSSGAQ
SVLKGPQPPLLVSLKPVAEVKGLCSVFPAQTPNNSNRQVLRVPFGESRSFLTSSPVNILT
SSQSISDTFVKEVLKWRYEMFVNFDQCGPPSSLCQSIARRVPIRFQDCGDYFSVFFPLMV
LNTFETVAQEWISSPNKEKFHQLHLRKFPGDYKKYWEFVVYLEEGELAKQLHPRENDLVF
LVPERLNEEKKDLEWSHLEDACEYYCGYVHKFRRTSVMHNGKSECSVSIQTQDNLPVNLN
ELVKCFVISSLVTTQRKLKAMSLLSGRNQLARAILNPNPMDFCTKDLLTTTSERIVAYLK
DFNDDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGILYRLLTENQRRGHSDE
NSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPMGNCGDINLVRLGPEKSI
NNEVLRFSLDSQVNHRMKKDLPSHVQEMHKRKEFLDRQLDELSRQRALCRGGRESQRQEL
DGKIARVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLEAAFRGQGG
VPFSCVIVDEAGQSCEVETLTPLIHRCNKLVLVGDPKQLPPTVISVKAQDYGYDQSMMAR
FHKLLEESVEHNMIGRLPVLQLTIQYRMHPDICLFPSSYVYDGILKTNRGTETSRCSSDW
PFQPYLVFDVGDGLERRDNDSYVNVQEIKLVMELIKLIKDKRRDINFRNIGIITHYKAQK
TMIQKDLDKEFDRKGAAEVDTVDAFQGRQKDCVIVTCVRANATQGSIGFLASLQRLNVTI
TRAKYSLFILGHLRTLVENRHWYHLIQDAQKRGAIIKTCDKNYRHDAMKILKLKPLLQRS
LTHPPAVAPEASRPQGGLPSKQDGELSKTSFASSLYHSPSDSKEATVTEAAKDPERPPTQ
DRLRDPRLLRRMGLAFDAQGISLREPQPLSPQHSGAAPPSGAPGCPGSPQEPCTVRQQGV
TLNSHMPHTQCDSPAAGTDTSTSKKKCDQEEGVLSHRRETRALSEGDQEWWASSHTKRNS
DWDERGLEEDSHSKKRRVL
NT seq
7980 nt
NT seq
+upstream
nt +downstream
nt
atgagtacatgttgttggtgtaccccagggggtacttccaccactgacttcctgcaacgc
tatgcatccaagacccgctccagtgaatttcagacagctgatgaagacctctgctactgc
ttggagtgtgtggctgaataccacaaagcaagggacgaattgccgttcttacatgaggtt
ttatgggaattagaaaccttacgtctcataaatcactttgaaagatccatgaaggcagaa
attggagatgatgatgagttatatatagtagacaacaacggagaggcacagctgttcgac
ttcactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccatatttgcttttacatgagcatgtcaatgaattatgtgttgaagcactttgccggatg
gaacaagctaattgttcctttcaagtttttgacaaacatccagggatctatctatttttg
gttcatcccaatgaaatggttcggcgttgggctatcctgactgcaagaaacttggggaaa
gtggatagagatgattactatgacttacaggaggttttgacttgcctttttaaagttatt
gagttgggacttttagaaaacccagacatttatacttcttctgtccttgagaagggtaaa
ctggttcttctgccttcacacatgtatgatactgccaactacaaaaactattggttaggt
atttgcatgctgcttaccattcttgaggagcaagccatggattcactgttgttgggctca
gataaacagaatgattttatgcagtcaatacttcataccatggagaggcaatcaaatgat
gatagtgtggatcctttctggccagcgttacactgtttcatggtgattctggatcgcctt
ggatctaaggtctggggtcaacttattgatcctattgaagcatttcaaaccattattaac
aacgtgagctacaatagagagatccagaacatacggaacagctgtatgaggaccaagtta
gaaccggagtcatatttggatgatatggtgacttgcagccagattgtatacaattataac
cctgaaaagaccaaaaaggattcagggtggagatcagccatttgccccgattattgtcct
aacatgtatgaagaaatggaaacattagctaacgtgctccagtcagatattggtcaggac
atgcgtgttcataacagcacatttctgtggttcatccctttcgtgcaatccctcatggac
ctgaaggatctgggtgtggcttacatagtggaggttattcaccatctgtactctgaagtc
aaagatgttctcaaccagacagacgctgtgtgtgacaaagtcactgagtttttccttctg
attttggtgtccgtgattgaactgcatagaaataaaaaatgtctacatttgctgtgggtt
agttcccagcagtgggtggaggctgtggtgaagtgtgccaagctaccgaccacagcgttt
gcacggagttccgagaagtcatctggaaactgttcgaagggcacagcaatgatatcatcc
ctgtcactgcattcaatgccctccaactctgtgcagctggcttgtgtgcagctgattaga
agtctcctgaaagaaggctatcagcttgggcagcagactctctgtaaacggttccgggat
aaactcaacttgttcctgcgagggaatttatctttaggttggcagttgactagtcaggaa
acccatgagctacaaacttgtttaaagcaaattattaggaacataaaattcaaagtacct
cagtttagcacttctgtggatctgaatcctgcatgtaagacgcctcctgcatcttttaaa
gaagaaagtgaacaaatagggaagaagtctgaaaaagatgtgtactgtctggaaaattcc
agcccaacatcttctaaagaaccaatgaaagctgatgcatatcaagtgcaagagagtatt
ttgagcaaagcaaataatgccatagaagagagtaaagagccatgttatataaaagatttg
aaactagaaggccacctctcagctgagtcatgtttgaagctgagtagtaaaaaccttgcc
tgtgaaagagttcaaaatcaagttaaaataagtacagggaaatataagtctgtaaaagag
aattcctcatgtaccccacaggatggtactttaagaaatggtccagaaaaagtatttgac
agaggaataataatatcaaggcgcttattgactgtttctagcacggattctatggaaaaa
gtgtctgcctccaatgaggacttctctttaaaggatgatgatcttggcaaaagctcaaca
gcaaaatctaagacacataaagatggagtctgtgctaagttgtcacatgtaataaaaaag
caacacaggaaaagtatcagtttagaggaaaacctggctgtatctagcattgagggtttc
tattcagagaaagatataggaggtcagaaaggaggtgggaacatatgcactccttcttta
gtccctaatggtattctggatgataaaaatggagaacaaaaatctcaaagctgtttattg
ctgagaaagaaagaagtaaagaaagaaaagttagatattttttctacccctgaaaacagt
tgtcaaatacaggaatgtcatgttgataccaaagatttggtctcactcacagaaatgacc
aatactttcatgacgaaagcatctccctttaaagagcctgtgactgggcatgaattgaga
gataggaaaattagtaggagcactgatcaattttcttctaatttaagagaacaggacctt
agcagcagtccccagcctgacaccttaacagattctcaggtagatagagacctccacaaa
ttatctttaatggctcaagccagtgttactaagttcccatcagattcaactcaaaaaagt
ttatcccaaatacaaagaaaagtaaaagatgagaaaagatgtttcacagcaaaccaaaat
atcagggaaacctgccatggacaggttattattatttcagattccgatgaggaggaggag
gaggaaagaatcctgggtttgaaggaacaaatgaaagagatcaaagcatgcattgagaaa
gaatgtccagagcaacatacttcaatagctaacacaaatgtggaacagaaggtattaata
aaggaagaaaatccaatgtcccttttgcagtttgaggaatctgattctcagttttttgag
tttgagactccatgtgaagtgttttcagtttggcatgatcagaaaccagacaagaattca
gctcaagagaatgagaaaaatccatgctcgactcctgtgggtgatactgcaaatgatttg
ggttatgagacagattatgtatctgaagaggtcattaaaaaagtagcagagaactttgaa
gagcgcacaaaaccacgtagtagtagtacttctgttgaggaattttgtgaaattgaagta
aaaaaacccaagagaagacggtatgaaaaacctatagctgaagatcctctaaggccttca
tcttctgtcaaaaatgaggaccagtcaaacaaggggaatctgagtaaaaatgattttaaa
ggtgtagacccaagagctacagttcccagttcaagtgttcagagaaacgctgcggtttcc
ccaaagaagtctcttccaaagcctcgcacgtattccagacctgtcaggaaagttccagtg
gttaaagcttctaagaaatccccttcagataccaagaaaggacagagtaaaagctcccat
tacataagctgtagaacaactcctgctattgtgccgccaaagaaatttcgccagtgtccc
gaaccaacttcaacagttgagaaacttggcctgaaaaaggctcctcgtagggcgtttgaa
ttgtcccagcgatctttagagtgtatagatcagctacgtgaccatggcagatctgttgga
gtagtggatacccggaaaaagacaaagttaatttctcctcagactctctctgtcagaaat
aataagaaactgctgacgagtcaagaccttcagttgcataggcagatgagatccaaatca
caacacaacagacaaggacgttttgattgtcgaagtacagataagacacgagcagggcca
tgtgctgcacagagctctgctgtgccggagtcaagtaagtcagattacagtcatcacgga
ggagccgaggtgactgctaacaataagggaaaacaattactaacatgtcagtcttctgaa
acagaacccgtgaaagcaaaccagtgtaatcctgtcatggtaaatggaagaacagcaaca
actgaagccattgttcctacctcagaggccctgttaggcagaggtgacccaacagtccat
catttagaggtggcgactttgaaagagggagagcctgaattcagcagtgacatagaggag
gaggatatattcttaacacagcgtgaccctgaagacatggatttatgttcacaaattgag
ggagagtatgataaactcattgaagtcattgatggaaaagataccgtgcagggagaggaa
gaatgtgtgaggcagcctcagttggaatctttgagtagcacaaaatgtaggtacaaagat
tgtgttgaaactctgaaaaacccgggtgaatactgctcaaaacactcaaaaactaaagcc
acagatgaagatacatttcgtaaacctggcttgcctctgtctgcatcaaaacgttcgaga
ccttccacgaccaaggtttttagttcaagcagtacttcacggattgctggtctctccaag
tctttggaaagtaccgcatccctcccatcatgtctgaaaaacaagtcaagtggggcacag
tctgttctgaaaggaccacagccaccccttctggtgtctctgaagccagtggctgaagtg
aaaggtctgtgcagtgttttccctgctcagactccaaataactccaacaggcaagttttg
agagttccatttggggaaagcagatcttttttgacttcctctccagtaaacattctcacg
tcgtcacagtccatctctgatacctttgtaaaagaggtcttgaaatggagatacgagatg
tttgtgaactttgatcagtgtgggcccccgtcgagtctgtgtcagtccatcgcaagacgg
gtgcctatcaggtttcaagactgtggagattatttcagtgtgtttttccctttgatggta
ctgaatacttttgaaacagtggcacaggaatggatcagctctccaaacaaagagaaattc
catcagttgcatttacgaaaatttcctggtgattataaaaaatactgggagtttgtggtt
tatcttgaggaaggtgaactagctaaacagcttcatccaagggaaaatgatttggtgttt
ttggttcctgaaagactcaatgaggagaagaaagatttagagtggagtcacctggaggat
gcctgtgaatattactgtggctatgttcataaattccgccgtacttcagtcatgcataat
gggaaatctgagtgttcggtttccatccagactcaagataatttaccagtcaatttaaat
gaactcgtgaaatgctttgtaatcagctctctggtgactacacaaaggaagttgaaagcc
atgtctttgctgagtggtcggaaccaactggccagagccattctgaatccaaaccccatg
gacttctgtacaaaagatttactaactacaacgtctgagagaattgttgcctacttaaaa
gatttcaatgacgaccagaagaaagcgatagaaactgcatatgccatggtgaaacactcc
ccgtcagttgccaagatctgtctgattcatggaccacctggaacaggaaaatcaaaaacc
attgttggcatcctgtaccgcctgctgaccgagaaccaaaggagggggcattcagatgaa
aactccaatgccaaaatcaagcaaaaccgtgtcctcgtatgtgcaccttccaatgcagct
gttgatgaacttatgaaaaaaattatccttgaattcaaagaaaagtgtaaagacaagaag
aatcctatgggaaactgtggagatataaacttagtacgtctaggtccagaaaagtctatt
aataatgaggtcctaagattcagtttggacagtcaagttaaccacagaatgaaaaaagac
ttaccgtctcatgttcaggagatgcacaaaagaaaggaatttctcgatcgtcaacttgat
gaactttcccgccagcgtgctttatgccgaggtggaagggaatcgcagaggcaagaatta
gatggaaaaattgccagagtttcaaaagaaaggcaggagcttgcttctaaaattaaagag
gttcaaggacgcccacagaagacacagagcatcatcatcttagagtcgcacatcatttgc
tgcacgctgagcacgagtggtggcctgctgctcgaggctgctttccgtgggcagggaggc
gtccccttcagctgtgtcatcgttgatgaggctggacagtcctgtgaagttgaaactctt
actccactcatccatcgttgcaacaagcttgtcctcgtaggagaccctaagcagctccct
cccacagtcatttccgtgaaggcacaggactatggctatgaccagtcaatgatggcccgc
ttccacaagctcctggaggagagtgtggagcacaacatgattggcaggctgcctgtctta
cagctcaccatccagtacaggatgcacccggacatatgcctctttccttctagttacgtt
tatgacggaatcttgaaaacaaatagagggacagagaccagtcggtgctcatctgactgg
ccatttcaaccctacctcgtgtttgatgttggagatggcttagaaagacgggataatgac
tcatatgtaaatgttcaagagataaaactggtaatggaactaattaaacttattaaagac
aaaagaagggacattaatttccgaaacattggcataataacccattacaaggctcagaag
acgatgattcagaaggatttggacaaagagtttgatagaaaaggggcagcagaagtagat
accgtggatgccttccagggtcgtcagaaagactgtgttattgttacatgtgtcagagca
aatgccacacaaggctcaattggatttctggcaagtttgcagagattgaatgtcaccatc
acacgagccaagtacagcctcttcatcctgggacacttgagaaccctagtggaaaatagg
cattggtatcacctgattcaagatgcacagaagcgtggcgccattattaagacttgcgac
aagaactacagacacgatgcaatgaagatcctgaagctcaaaccattgcttcagaggagc
cttactcaccctcctgctgtcgctccagaggcatccagaccccagggtggcctacccagc
aagcaagatggtgaactcagcaagacatcttttgcttcttccctgtaccactcaccctct
gattccaaagaagccacagtcactgaggctgcaaaggatcctgaaaggccacccactcag
gaccggcttcgggacccaagactgctgcggaggatgggcttagcctttgatgcccaagga
ataagcctcagggagccgcagcccttgagcccccagcattccggagcagcgcctccatca
ggcgcgccaggctgccctgggagtccccaggagccatgcaccgtcaggcagcagggagtc
accctgaacagccacatgcctcacacgcagtgcgactctccagccgctggtactgacact
tccacaagcaaaaagaagtgtgaccaggaagagggggtgctcagccacaggagagagacc
agggccttgagtgaaggggatcaggagtggtgggcgagctcccacacaaagaggaactca
gactgggatgagaggggcctggaggaggacagccactcaaagaagagacgggttttatag
DBGET
integrated database retrieval system
