Capra hircus (goat): 102179919
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Entry
102179919 CDS
T02910
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
chx
Capra hircus (goat)
Pathway
chx00260
Glycine, serine and threonine metabolism
chx00630
Glyoxylate and dicarboxylate metabolism
chx00670
One carbon pool by folate
chx01100
Metabolic pathways
chx01200
Carbon metabolism
chx01230
Biosynthesis of amino acids
chx01240
Biosynthesis of cofactors
chx01523
Antifolate resistance
chx04981
Folate transport and metabolism
Module
chx_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
102179919 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
102179919 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102179919 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102179919 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102179919 (SHMT2)
Enzymes [BR:
chx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
102179919 (SHMT2)
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
102179919
NCBI-ProteinID:
XP_005680363
UniProt:
A0A452DPN1
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Position
5:complement(55535952..55541317)
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AA seq
502 aa
AA seq
DB search
MLSFSFIWATRPLRRCGQLVGMAIRCQHSEATQTGEASKGWSGQESLSDSDPEMWELLRR
EKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRR
ALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMTDVKR
VSATSIFFESMPYKLNPQTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYACMRKVCD
EVKAHLLADIAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVQAVDPK
TGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPVFREYSLQILKNAQAMA
DALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPG
GLRLGAPALTSRGFREDDFRKVVGFIDEGVNIGLEVKSKTTKLQDFKSFLLKDPETSHQL
ADLRQRVEQFARAFPMPGFDDH
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
atgttgtccttctcttttatttgggcgactcggcctctgcggagatgtggtcagctggtt
gggatggccatacggtgccagcacagtgaggcgactcagactggagaagcaagcaagggc
tggtcaggccaggagagtctatcagacagtgaccctgagatgtgggagctgctgcggaga
gagaaggacaggcagtgtcgtggcctggagctcattgcttcagagaacttctgcagccga
gctgcgctggaggccctggggtcctgtctgaacaacaagtactccgagggttatcctggc
aagagatactacggaggagcagaggtagtggatgagatagagctgctgtgtcagcgccgg
gccttggaggcctttgacctggatcctgctcagtggggagtcaatgtccaaccctactcc
ggatccccagccaatctggctgcctacacagcccttctgcagcctcacgaccgaatcatg
gggctggacttgcccgatgggggccatctcacccatggctacatgactgatgtcaagcgg
gtctcagctacatccatcttcttcgagtctatgccttataagctgaacccccaaaccggc
ctcattgactatgaccagctggcactcactgctcggctcttcagaccacgactcatcata
gctggtaccagtgcctatgcgcgcctcattgactacgcctgcatgagaaaagtgtgtgac
gaggtcaaggcacacctcttggcagacatagcccacatcagtggcctggtggctgccaag
gtgatcccctcacccttcaagcacgcagatatcgtcaccacgaccactcacaagaccctt
cgaggggccaggtcaggactcatcttctaccggaagggggtgcaggctgtggaccccaaa
actggccgagagatcccttacacatttgaggaccgaatcaactttgctgtgttcccatcc
ctgcaggggggcccccacaaccatgccattgctgcagtggctgtggccctaaagcaggcc
tgcacccccgtgttccgggagtactccctgcagattctgaagaacgctcaggccatggct
gatgccctgctggagcgaggctactccctagtgtctggtggcactgacaaccacctagtg
ctggtggacctgcggccaaagggcctggacggagctcgagcagaacgggtgttggaactt
gtatccatcacggccaacaagaacacctgtcctggagatcgaagtgccatcacacctggg
ggcctgcggctgggggccccagccctgacttctcgagggttccgtgaagatgacttccgg
aaagttgtaggctttatagatgaaggtgtcaacattggcttggaagtgaagagcaagacc
accaaactccaggatttcaaatctttcctgctcaaagacccagaaacaagtcatcagctg
gccgaccttaggcaacgggtggagcagttcgccagggccttccccatgcctggctttgat
gatcactga
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