Capra hircus (goat): 102180953
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Entry
102180953 CDS
T02910
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X2
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
chx
Capra hircus (goat)
Pathway
chx05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102180953 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
chx01002
]
102180953 (BACE1)
Enzymes [BR:
chx01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
102180953 (BACE1)
Peptidases and inhibitors [BR:
chx01002
]
Aspartic peptidases
Family A1: pepsin family
102180953 (BACE1)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
102180953
NCBI-ProteinID:
XP_013824921
EnsemblRapid:
ENSCHIG00000018165
UniProt:
A0A452F468
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All DBs
Position
15:54352205..54373787
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AA seq
501 aa
AA seq
DB search
MAQALPWLLLWMGSGVLPAHGSQPGIRLPLRSGLGGAPLGLRLPRETDEESEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEALASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAVCALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagcactgccctggctccttctgtggatgggctccggggtgctacctgcccac
ggctcccagcccggcatccggctgcccttgcgaagtgggctggggggtgcccccctgggg
ctgcggctgccccgggagaccgacgaggagtctgaggagcccggccggaggggcagcttt
gtggagatggtggacaacctgaggggcaagtccgggcagggctactacgtggagatgacc
gtgggcagccccccacagacgctcaacatcctggtggacacaggcagcagtaacttcgca
gtaggggctgccccccaccctttcctacaccgctactaccagaggcagctgtccagcacg
taccgggacctccggaagggcgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggtaccgacctggtgagcatcccccacggccccaacgtcaccgtgcgcgccaacatt
gctgccatcacagaatcagacaagttcttcatcaatggctccaactgggaaggcatcctg
gggctagcctatgcagagatcgcccggcctgatgactccctggagccgttctttgactcc
ctggtgaagcagacccacgtgcccaatctcttctcactgcagctctgtggcgctggcttc
cccctcaaccagtcggaagcactggcctcagttggagggagcatgatcattgggggtatc
gaccactcactatacacgggcagcctctggtatactcccatcaggcgggagtggtattat
gaggtgatcattgtacgggtggagatcaatggacaggatctgaaaatggactgcaaggag
tacaactatgacaagagcatcgtcgacagtggcaccaccaaccttcgattacccaagaaa
gtgttcgaagctgctgtcaaatccatcaaagcagcctcctcgacggagaagttcccagac
ggattctggctaggggagcagctggtgtgctggcaagcaggcaccaccccgtggaacatt
ttcccagtcatctcactctacctaatgggcgaggtcaccaaccagtccttccgcatcacc
atccttccacagcaatacctgcggcccgtggaagatgtggccacctcccaagacgactgt
tacaagttcgccatttcacagtcgtccaccggcactgtcatgggagcggtcatcatggag
ggcttctacgttgtctttgatcgggcccggaaacgaatcggctttgctgtcagtgcttgc
catgtgcatgatgagttcaggacggcagcggtggagggccctttcgtcacccccgacatg
gaagactgcggctacaacatcccacagacggacgagtcgaccctcatgaccatagcctac
gtcatggctgccgtctgtgcgctcttcatgctgcccctctgcctgatggtgtgccagtgg
cgctgcctccgctgcctccgccaccagcacgacgactttgctgacgacatctccctgctg
aagtga
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