Capra hircus (goat): 102181989
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Entry
102181989 CDS
T02910
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
chx
Capra hircus (goat)
Pathway
chx01521
EGFR tyrosine kinase inhibitor resistance
chx01522
Endocrine resistance
chx01524
Platinum drug resistance
chx04010
MAPK signaling pathway
chx04012
ErbB signaling pathway
chx04020
Calcium signaling pathway
chx04066
HIF-1 signaling pathway
chx04151
PI3K-Akt signaling pathway
chx04510
Focal adhesion
chx04520
Adherens junction
chx04530
Tight junction
chx05200
Pathways in cancer
chx05205
Proteoglycans in cancer
chx05206
MicroRNAs in cancer
chx05212
Pancreatic cancer
chx05213
Endometrial cancer
chx05215
Prostate cancer
chx05219
Bladder cancer
chx05223
Non-small cell lung cancer
chx05224
Breast cancer
chx05226
Gastric cancer
chx05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102181989 (ERBB2)
04012 ErbB signaling pathway
102181989 (ERBB2)
04066 HIF-1 signaling pathway
102181989 (ERBB2)
04020 Calcium signaling pathway
102181989 (ERBB2)
04151 PI3K-Akt signaling pathway
102181989 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102181989 (ERBB2)
04520 Adherens junction
102181989 (ERBB2)
04530 Tight junction
102181989 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102181989 (ERBB2)
05206 MicroRNAs in cancer
102181989 (ERBB2)
05205 Proteoglycans in cancer
102181989 (ERBB2)
05230 Central carbon metabolism in cancer
102181989 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
102181989 (ERBB2)
05226 Gastric cancer
102181989 (ERBB2)
05219 Bladder cancer
102181989 (ERBB2)
05215 Prostate cancer
102181989 (ERBB2)
05213 Endometrial cancer
102181989 (ERBB2)
05224 Breast cancer
102181989 (ERBB2)
05223 Non-small cell lung cancer
102181989 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102181989 (ERBB2)
01524 Platinum drug resistance
102181989 (ERBB2)
01522 Endocrine resistance
102181989 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
chx01001
]
102181989 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
chx04147
]
102181989 (ERBB2)
04090 CD molecules [BR:
chx04090
]
102181989 (ERBB2)
Enzymes [BR:
chx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102181989 (ERBB2)
Protein kinases [BR:
chx01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
102181989 (ERBB2)
Exosome [BR:
chx04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
102181989 (ERBB2)
CD molecules [BR:
chx04090
]
Proteins
102181989 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
APH
CcmD
Motif
Other DBs
NCBI-GeneID:
102181989
NCBI-ProteinID:
XP_017920500
LinkDB
All DBs
Position
19:39713161..39737414
Genome browser
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPADASLSFLQEIQEVQGYVLIAHNRVSQVPLQRLRIVRGTQLFEEHYALAVLDNG
DFLEGAAPAAGTAPGGLQELQLRSLTEILKGGVLIQRNPQLCHQDTILWEDIFHKNNQLP
LKQIDTNRSRACAPCSPACKAPSCWGESSEDCQSLTRTVCASGCARCKGPQPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCAPVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLSESFAGDPDSNITPLQAEQLKVFESLEEITGYLYISAWPDSLP
DLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELSSGLALIHRNARLCFVHTV
PWDQLFQNPHQALLHSANRPEDECVGEGLACYPLCAQGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHPECLPQNGSVTCFGSEADQCVACAHYKDPPFCVARC
PSGVKPDLSFMPIWKFPDEEGICQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
VLLVVLVGLVFGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVTEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSTSTRSGGGELTLGLEPSEEEPPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQPLPQHDSSPLQRYSEDPTVPLSPEADGYVAPLTCSPQPEYV
NQPEVRPQPPSPLEGPLPPPRPAGSTLERPKTLSPGKNGVVKDVFAFGAAVENPEYLAPR
GRAAPQSHPSPAFSPAFDNLYYWDQDPSERGTPSSSFEGTPTAENPEYLGLDMPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctgccagccagtcccgag
acccacctggacatgctgcgccacctctaccaaggctgtcaggtggtacagggtaacctg
gagctcacctatctgcctgctgatgccagcctctccttcctgcaggaaatccaggaggtg
cagggctatgtgctcatcgctcacaatcgagtgagtcaggtcccactgcagagactgcga
atcgtgcgaggcactcagctctttgaggaacactatgccctggccgtgctggacaatgga
gactttctggaaggtgctgcccctgctgcgggtacggccccaggagggctgcaggagctg
cagctgcgaagcctcacagagatcctcaagggaggggtcttgatccagcggaacccccag
ctctgccaccaggacacgattttgtgggaggatatcttccacaagaacaaccagctgccc
ctcaagcagatagacaccaaccgctcacgggcctgcgcaccctgttctccagcttgtaaa
gctcccagctgctggggagaaagttctgaggactgtcagagcttgacgcggaccgtctgt
gccagtggctgtgcccgctgtaagggcccacagcccaccgactgctgccacgagcagtgc
gctgccggctgtactggccccaagcactctgactgcctggcctgcctccacttcaaccac
agcggcatctgtgagctgcactgcccagctctggtcacctacaacacggacaccttcgag
tcgatgcccaaccccgaggggcgttataccttcggtgccagctgtgtgaccgcctgtcct
tacaactacctgtctacggatgtgggatcctgcaccctggtttgtcccctgaacaaccaa
gaggtgacagctgaggatggaacccagaggtgtgagaaatgcagcaagccctgtgcccca
gtgtgctacggtctgggcatggaacacctgcgggaggtgagagcggtcaccagtgccaac
atccaggagtttgccggctgcaagaagatttttgggagcctggcgtttctgtcagagagc
tttgcaggggacccagactctaacatcaccccactgcaggctgagcagctcaaagtgttt
gagtctctggaggagatcacaggttacctgtacatctcagcgtggccagacagcctgcct
gacctcagcgtcttccagaacctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcgctgaccctgcaagggctgggcatcagctggctggggctgcgctcgctgcgggaa
ctgagcagcgggctggccctcatccaccgcaacgcccgcctctgcttcgtacacacggtg
ccctgggaccagctcttccagaacccccaccaggctctgctccacagcgccaacaggcca
gaggatgagtgcgtgggtgagggcctggcctgctacccactgtgcgcccaagggcactgc
tggggtcccgggcccacccagtgcgtcaactgcagccagttccttcggggccaggaatgc
gtggaggaatgccgagtactacaggggcttccccgggagtacgtgaaggacaggtactgt
ctgccgtgccaccccgagtgccttccccagaatggctcagtgacctgctttggctcggag
gctgaccaatgtgtggcttgtgcccactacaaggatcctcccttctgcgtggctcgctgc
cccagtggtgtgaagcctgacctctccttcatgcccatctggaagtttccagatgaggag
ggcatatgccagccatgccccatcaactgcacccactcctgtgtggacttggatgacaag
ggctgtcccgccgagcagagagccagccctgtgacatccatcattgctgctgtggtgggc
gttctgctggttgtccttgtggggctggtgttcggcatcctcattaagcgaaggcggcag
aagatccggaagtatacaatgcggcggctgctgcaggagacggagctggtggagcccctg
acgcccagcggagcgatgcccaatcaggctcagatgcggatcttaaaagagacagagctg
aggaaagtgaaggtgctaggatctggagcttttggcaccgtctacaagggcatctggatc
cccgatggggaaaatgtgaaaatccccgtggccatcaaggtgttgagggaaaacacatct
cccaaagccaacaaggaaatcttggacgaagcatatgtgatggctggtgtaggttcccca
tatgtgtcccgcctcctgggcatctgcctgacatccacagtgcagctggtgacacagctt
atgccctatggctgcctcctcgaccacgtccgagaacaccgtgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggatgtgcgg
ctcgtgcatagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtgaag
attacagacttcgggctagctcgactgctagacattgacgagacagagtaccacgcagat
gggggcaaggtgcccatcaagtggatggcattggagtccattctccgccggcggttcacc
caccagagtgacgtgtggagctatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttatgatgggatcccagcccgggagattcctgacctgctggagaagggagaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgtcggccgaggttccgggagttagtgactgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaagacttgggccctgctagccccctg
gatagcaccttctaccgctcgctgctggaggatgacgacatgggcgacctggtggatgcg
gaggagtacctggtacctcagcagggcttcttctgcccagaccctgccccaggagctgga
ggcacggcccaccgcaggcaccgcagcacatccaccaggagtggtggtggtgagctgaca
ctggggctggagccctctgaggaggagccccccagatctccgctggcaccttccgaaggg
gcaggctctgatgtgtttgatggcgacttgggaatgggggcggccaaggggctgcagccc
ctcccccaacacgactctagccctctacagcggtacagcgaggaccccacagtacccctt
tctcccgaggctgatggctacgttgcccccttgacctgcagcccccagcccgaatacgtg
aaccagccagaggttcgcccacagcccccgtcacccctagagggtcctctgccgcctcct
cgacctgcaggttccactctggaaaggcccaagacgctctcccctgggaagaatggggtt
gtcaaagacgtttttgcctttggggctgccgtggagaaccccgagtacttggcaccccgg
ggcagggccgcccctcagtcccacccttctccagccttcagcccagcctttgacaacctc
tactactgggaccaggacccatcagagcggggcactccatccagctcctttgaagggacc
cctacggcagagaaccctgagtacctgggtctggacatgccagtatga
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