Capra hircus (goat): 102184154 Help Entry 102184154         CDS       T02910                                  Symbol SOS2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism chx  Capra hircus (goat) Pathway chx01521   EGFR tyrosine kinase inhibitor resistance chx01522   Endocrine resistance chx04010   MAPK signaling pathway chx04012   ErbB signaling pathway chx04014   Ras signaling pathway chx04062   Chemokine signaling pathway chx04068   FoxO signaling pathway chx04072   Phospholipase D signaling pathway chx04150   mTOR signaling pathway chx04151   PI3K-Akt signaling pathway chx04510   Focal adhesion chx04540   Gap junction chx04630   JAK-STAT signaling pathway chx04650   Natural killer cell mediated cytotoxicity chx04660   T cell receptor signaling pathway chx04662   B cell receptor signaling pathway chx04664   Fc epsilon RI signaling pathway chx04714   Thermogenesis chx04722   Neurotrophin signaling pathway chx04810   Regulation of actin cytoskeleton chx04910   Insulin signaling pathway chx04912   GnRH signaling pathway chx04915   Estrogen signaling pathway chx04917   Prolactin signaling pathway chx04926   Relaxin signaling pathway chx04935   Growth hormone synthesis, secretion and action chx05034   Alcoholism chx05160   Hepatitis C chx05161   Hepatitis B chx05163   Human cytomegalovirus infection chx05165   Human papillomavirus infection chx05200   Pathways in cancer chx05205   Proteoglycans in cancer chx05206   MicroRNAs in cancer chx05207   Chemical carcinogenesis - receptor activation chx05208   Chemical carcinogenesis - reactive oxygen species chx05210   Colorectal cancer chx05211   Renal cell carcinoma chx05213   Endometrial cancer chx05214   Glioma chx05215   Prostate cancer chx05220   Chronic myeloid leukemia chx05221   Acute myeloid leukemia chx05223   Non-small cell lung cancer chx05224   Breast cancer chx05225   Hepatocellular carcinoma chx05226   Gastric cancer chx05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:chx00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102184154 (SOS2)    04012 ErbB signaling pathway     102184154 (SOS2)    04014 Ras signaling pathway     102184154 (SOS2)    04630 JAK-STAT signaling pathway     102184154 (SOS2)    04068 FoxO signaling pathway     102184154 (SOS2)    04072 Phospholipase D signaling pathway     102184154 (SOS2)    04151 PI3K-Akt signaling pathway     102184154 (SOS2)    04150 mTOR signaling pathway     102184154 (SOS2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     102184154 (SOS2)    04540 Gap junction     102184154 (SOS2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     102184154 (SOS2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     102184154 (SOS2)    04660 T cell receptor signaling pathway     102184154 (SOS2)    04662 B cell receptor signaling pathway     102184154 (SOS2)    04664 Fc epsilon RI signaling pathway     102184154 (SOS2)    04062 Chemokine signaling pathway     102184154 (SOS2)   09152 Endocrine system    04910 Insulin signaling pathway     102184154 (SOS2)    04912 GnRH signaling pathway     102184154 (SOS2)    04915 Estrogen signaling pathway     102184154 (SOS2)    04917 Prolactin signaling pathway     102184154 (SOS2)    04926 Relaxin signaling pathway     102184154 (SOS2)    04935 Growth hormone synthesis, secretion and action     102184154 (SOS2)   09156 Nervous system    04722 Neurotrophin signaling pathway     102184154 (SOS2)   09159 Environmental adaptation    04714 Thermogenesis     102184154 (SOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102184154 (SOS2)    05206 MicroRNAs in cancer     102184154 (SOS2)    05205 Proteoglycans in cancer     102184154 (SOS2)    05207 Chemical carcinogenesis - receptor activation     102184154 (SOS2)    05208 Chemical carcinogenesis - reactive oxygen species     102184154 (SOS2)    05231 Choline metabolism in cancer     102184154 (SOS2)   09162 Cancer: specific types    05210 Colorectal cancer     102184154 (SOS2)    05225 Hepatocellular carcinoma     102184154 (SOS2)    05226 Gastric cancer     102184154 (SOS2)    05214 Glioma     102184154 (SOS2)    05221 Acute myeloid leukemia     102184154 (SOS2)    05220 Chronic myeloid leukemia     102184154 (SOS2)    05211 Renal cell carcinoma     102184154 (SOS2)    05215 Prostate cancer     102184154 (SOS2)    05213 Endometrial cancer     102184154 (SOS2)    05224 Breast cancer     102184154 (SOS2)    05223 Non-small cell lung cancer     102184154 (SOS2)   09172 Infectious disease: viral    05161 Hepatitis B     102184154 (SOS2)    05160 Hepatitis C     102184154 (SOS2)    05163 Human cytomegalovirus infection     102184154 (SOS2)    05165 Human papillomavirus infection     102184154 (SOS2)   09165 Substance dependence    05034 Alcoholism     102184154 (SOS2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102184154 (SOS2)    01522 Endocrine resistance     102184154 (SOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH RHG20_PH PH_19 Motif Other DBs NCBI-GeneID:  102184154 NCBI-ProteinID:  XP_017909860 UniProt:  A0A452G3I9 LinkDB All DBs Position 10:59890326..59991899 Genome browser AA seq 1332 aa AA seqDB search MQQAPQPYEFYSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI EKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKI CSEEHEDRECLNQAITALMNLQGSMDRIYKQFSPRRRPGDPVCPFYNRQLRSKHLAIKKM NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG CSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIYAAKSAEEKNNWMAALI SLQYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLTERFEIPEPEPTEADKLA LEKGEQPISTDLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLEFFISSVR GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGCASEKEFTDYLFNKSLEIEPRNCK QPPRFPRKSAFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS EEPLIPPPLPPRKKFDQDASNSKGTMKSDDDPPAIPPRQPPPPKVKPRVPAPTGPFDGPL HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFTLQPPPLGHLHRDPDWFRDVNTCPNSPN TPPSTPSPRVPRRCYVLSSSQNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPMY RLPLLENAETPQ NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt atgcagcaggcgccgcagccttacgagttctacagcgaagagaacagtccgaaatggcgg ggactgttggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctcagct aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat ccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaaagaaga aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac aaagtggactaccatgtatccctatatattgtggctgtgctagagtatatctcagctgat attttgaaattggctggtaattatgtttttaatatccgacattatgaaatatctcaacaa gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac ataggcttggtttctctttgtgaagatgaacctagttcttcaggcgaattaaactactat gaccttgttagaactgaaattgcagaagaaagacagtatctacgggaactaaatatgatc ataaaagtgtttcgagaagcttttctttctgacagaaagctgtttaaaccttctgatatt gaaaagattttcagtaacattttagatatacatgagttgactgtgaaacttttaggttta attgaagacacagttgaaatgactgatgaaagtagccctcatcccttagctggcagctgt tttgaagatctggcagaggagcaagcatttgatccttatgaaacattatcccaggatatt ctttcaccaaagtttaatgaacattttagtaagttgatggccagacctgcagtggctcta cactttcagtccattgctgatggttttaaagaggcagttcgttacgtccttccacgcctt atgctggtgccagtatatcattgttggcactattttgagttattaaagcaattgaaaata tgtagtgaagagcatgaagacagagaatgtttgaaccaagctattactgctctcatgaat ctccaaggtagtatggaccgaatttacaagcagttttcacctagacgccgacctggggat cctgtttgccctttttataatcgtcagttaagaagcaagcacctggctattaaaaaaatg aatgaaattcagaaaaacatagatggatgggaaggcaaagacattggacagtgttgtaat gaatttattatggaaggcccattgacaagaattggtgctaaacacgaaaggcatattttt ctctttgacggcttaatgatcagctgcaaacccaaccacagccagtcacgcctcccagga tgcagcagtgcagagtacagactaaaagagaaattcgtcatgaggaagatacagatatgc gataaagaagatacttgtgagtgcaagcacgcttttgagttagtatccaaagatgaaaac agcataatatatgctgctaagtctgctgaagagaaaaataactggatggcagcacttatt tcccttcagtatcgtagtactctggatcgaatgctggattcggtattattgaaggaagaa aatgaacaaccattgagattaccaagtcctgaagtgtatcgttttgtggtgaaagactct gaggaaaacattgtttttgaagacaacttgcagagtagaagtggaatccccattattaaa ggaggaactgtggtgaaattaattgaaaggctaacatatcatatgtacgcagatcccaat tttgttcgtacctttcttactacgtaccgttcattttgtaaaccacaggaattactaagc ttactgactgaacgatttgaaattccagagccagaacctactgaagcagataaattggca ttagaaaaaggcgagcagcccatcagtacagaccttaaaaggtttcgcaaggaatacgtc caaccagtacaacttagggtcttaaatgtgtttcggcactgggttgaacaccatttttat gactttgaaagagacttggagctgcttgaaagactagaattcttcatttcaagtgtaaga gggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaaaaaacaa gctcaggcaaatggtataagccataatattacctttgaaagtccacctccaccaattgaa tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacacttcatccaata gaaattgcacgtcagctgacccttttggaatctgatctctacaggaaagttcaaccttct gaacttgtagggagtgtatggaccaaagaagataaagaaataaactctccaaatttatta aaaatgattcgccacaccacaaatctcaccctctggtttgaaaaatgcattgtggaggca gaaaattttgaggaacgggtggcaatactgagtagaattatagaaattctgcaagttttt caagatttgaataatttcaatggtgtattggagatcgtcagtgcagtaaattcagtatca gtctatagactagatcatacctttgaggcgttgcaggaaagaaaaaggaaaattttggat gaagctgtggaattaagtcaagatcattttaaaaaatatctagtgaaacttaagtcaatc aatccaccctgtgtgcctttttttggaatatatttaacaaatatactgaagactgaagaa gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg aaagtagctgaaattactggagaaattcagcagtatcaaaatcaaccttactgtttacgg atagaaccagaaatgaggagattctttgaaaaccttaacccaatgggatgtgcttctgaa aaagagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaactgcaaa cagccacctcgatttcctaggaaatcagctttctccttaaaatctcctggaataaggcct aatacaggccgacatggctctacctcaggtactttgcgaggtcacccaacaccattagaa agagaaccgtgtaaaataagctttagtcggattgctgaaacggagcttgaatcaacagtg tcagcaccaacctctccaaatacaccatctaccccaccagtatctgcttcttcagacctt agtgtgtttttagatgtggatctcaacagttcctgtggaagcaatagcatctttgctcca gtcctcttgcctcattcaaagtctttcttcagttcgtgtggtagtttacataagctaagt gaagagccactgattcctcctccacttccacctcgaaaaaaatttgatcaggatgcttca aattccaagggaactatgaaatctgatgatgatccccctgctattccaccaagacaacct cctcctccaaaggtaaaacccagagttcctgctcctactggtccatttgatgggcctctg catagtccacctccaccaccaccgagagatcctcttcctgatacccctccaccggttcca cttcggcctccagaacactttataaactgtccgtttactcttcagccacctccactggga catcttcacagagatccagactggttcagagacgttaatacgtgtccaaattctccgaac actcctcctagcacaccctctccaagggtacctcgtcgatgctatgtgctcagttctagt caaaataatcttgctcatcctcaagctccccctgttccaccaaggcagaattcaagccct catctaccaaaactgccaccaaagacttacaaacgggagctttcacaccccccaatgtat agactgccattgttagaaaatgcagaaactcctcaatga

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