KEGG   Capra hircus (goat): 102185084
Entry
102185084         CDS       T02910                                 
Symbol
CAMK2A
Name
(RefSeq) calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
  KO
K04515  calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
Organism
chx  Capra hircus (goat)
Pathway
chx04012  ErbB signaling pathway
chx04020  Calcium signaling pathway
chx04024  cAMP signaling pathway
chx04066  HIF-1 signaling pathway
chx04114  Oocyte meiosis
chx04148  Efferocytosis
chx04217  Necroptosis
chx04261  Adrenergic signaling in cardiomyocytes
chx04310  Wnt signaling pathway
chx04360  Axon guidance
chx04713  Circadian entrainment
chx04720  Long-term potentiation
chx04722  Neurotrophin signaling pathway
chx04725  Cholinergic synapse
chx04728  Dopaminergic synapse
chx04740  Olfactory transduction
chx04750  Inflammatory mediator regulation of TRP channels
chx04911  Insulin secretion
chx04912  GnRH signaling pathway
chx04916  Melanogenesis
chx04921  Oxytocin signaling pathway
chx04922  Glucagon signaling pathway
chx04925  Aldosterone synthesis and secretion
chx04934  Cushing syndrome
chx04971  Gastric acid secretion
chx05012  Parkinson disease
chx05022  Pathways of neurodegeneration - multiple diseases
chx05031  Amphetamine addiction
chx05152  Tuberculosis
chx05200  Pathways in cancer
chx05205  Proteoglycans in cancer
chx05214  Glioma
chx05415  Diabetic cardiomyopathy
chx05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:chx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102185084 (CAMK2A)
   04310 Wnt signaling pathway
    102185084 (CAMK2A)
   04066 HIF-1 signaling pathway
    102185084 (CAMK2A)
   04020 Calcium signaling pathway
    102185084 (CAMK2A)
   04024 cAMP signaling pathway
    102185084 (CAMK2A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102185084 (CAMK2A)
  09143 Cell growth and death
   04114 Oocyte meiosis
    102185084 (CAMK2A)
   04217 Necroptosis
    102185084 (CAMK2A)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    102185084 (CAMK2A)
   04922 Glucagon signaling pathway
    102185084 (CAMK2A)
   04912 GnRH signaling pathway
    102185084 (CAMK2A)
   04921 Oxytocin signaling pathway
    102185084 (CAMK2A)
   04916 Melanogenesis
    102185084 (CAMK2A)
   04925 Aldosterone synthesis and secretion
    102185084 (CAMK2A)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102185084 (CAMK2A)
  09154 Digestive system
   04971 Gastric acid secretion
    102185084 (CAMK2A)
  09156 Nervous system
   04725 Cholinergic synapse
    102185084 (CAMK2A)
   04728 Dopaminergic synapse
    102185084 (CAMK2A)
   04720 Long-term potentiation
    102185084 (CAMK2A)
   04722 Neurotrophin signaling pathway
    102185084 (CAMK2A)
  09157 Sensory system
   04740 Olfactory transduction
    102185084 (CAMK2A)
   04750 Inflammatory mediator regulation of TRP channels
    102185084 (CAMK2A)
  09158 Development and regeneration
   04360 Axon guidance
    102185084 (CAMK2A)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102185084 (CAMK2A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102185084 (CAMK2A)
   05205 Proteoglycans in cancer
    102185084 (CAMK2A)
  09162 Cancer: specific types
   05214 Glioma
    102185084 (CAMK2A)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    102185084 (CAMK2A)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    102185084 (CAMK2A)
   05022 Pathways of neurodegeneration - multiple diseases
    102185084 (CAMK2A)
  09165 Substance dependence
   05031 Amphetamine addiction
    102185084 (CAMK2A)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102185084 (CAMK2A)
   05415 Diabetic cardiomyopathy
    102185084 (CAMK2A)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102185084 (CAMK2A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:chx01001]
    102185084 (CAMK2A)
Enzymes [BR:chx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     102185084 (CAMK2A)
Protein kinases [BR:chx01001]
 Serine/threonine kinases: CAMK group
  CAMK2 family
   102185084 (CAMK2A)
SSDB
Motif
Pfam: Pkinase CaMKII_AD PK_Tyr_Ser-Thr DUF4440 SnoaL_3 SnoaL_2 Kdo SnoaL_4
Other DBs
NCBI-GeneID: 102185084
NCBI-ProteinID: XP_005683225
UniProt: A0A452G1X0
LinkDB
Position
7:48785985..48851816
AA seq 489 aa
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQE
IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP
VHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHR
SGAPSVLPH
NT seq 1470 nt   +upstreamnt  +downstreamnt
atggccaccatcacctgcacccgcttcacggaagagtaccagctcttcgaggaactagga
aagggagccttctcagtggtgcgcaggtgtgtgaaggtgctggccggccaggaatatgct
gccaagattatcaacacgaagaagctctcggccagagaccaccagaagctggagcgtgaa
gcccgcatttgccgcctgctgaagcaccccaatatcgtccggctccacgacagcatctct
gaggagggacaccattacctgatctttgacctcgtcaccggcggggagctgtttgaagac
attgtggcccgggagtattacagtgaggcggatgccagtcactgcatccagcagatcctg
gaggccgtgctgcactgccaccagatgggggtggtgcaccgggaccttaagccggagaac
ctgttgctggcctccaagctcaagggcgctgcagtgaagctggcggactttggcctggcc
atagaggtagagggcgagcagcaggcatggtttgggttcgcagggacacccggatacctc
tccccagaagtgctgcggaaggacccatacgggaagcccgtggacctgtgggcctgcggg
gtcatcctgtacatcctgctggtggggtaccccccgttctgggatgaggaccagcatcgc
ctgtaccagcagatcaaagctggggcctatgatttcccatcaccagaatgggacaccgtt
accccggaagccaaggatctgatcaataagatgctgaccatcaacccatccaaacgcatc
acagccgctgaggccctcaagcacccctggatctcgcaccggtccaccgtggcctcctgc
atgcacagacaggagaccgtggactgcctgaagaagttcaacgcgaggagaaaactgaag
ggagccattctcaccactatgctggccaccaggaacttctctggcgggaagagtggggga
aacaagaagaacgatggtgtgaagaaaagaaagtccagttccagcgttcagttaatggaa
tcttcagagagcaccaataccaccattgaggatgaagacaccaaagtgcggaaacaagag
atcataaaagtgacagagcagctgattgaagccataagcaatggagattttgagtcctac
acgaaaatgtgtgaccctgggatgacggccttcgaacccgaggccctggggaacctggtc
gagggcttggacttccatcgattctattttgaaaacctgtggtcccggaacagcaagcct
gtgcacaccaccatcctgaacccccacatccacctgatgggtgacgagtcggcctgcatc
gcctacatccgcatcacgcagtacctggacgccggcggcatcccccgcacggcccagtcg
gaagagacccgcgtctggcaccgccgggatggcaaatggcagatcgtccacttccacaga
tccggggcgccttccgtcctgccgcactga

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