| Entry |
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| Symbol |
ABCC5
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| Name |
(RefSeq) multidrug resistance-associated protein 5 isoform X1
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| KO |
| K05668 | ATP-binding cassette, subfamily C (CFTR/MRP), member 5 |
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| Organism |
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| Pathway |
| chx04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:chx00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
102186159 (ABCC5)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102186159 (ABCC5)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102186159 (ABCC5)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:chx02000]
102186159 (ABCC5)
Transporters [BR:chx02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
102186159 (ABCC5)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
1:82810850..82893600
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| AA seq |
1437 aa
MKDIDIGKEYIIPSPGYRNVRERTSNSGQHRDREDSKYKRTQPLDCQDALETAARAEGLS
LDPSMHSQLRILDEEHPKGKYHHSLSVLKPIRTTSKHQHPVDNAGLFSCMTFSWLSPLAR
KAHKKGELLMEDVWSLSKHESSEVNCRRLERLWQEELNEAGPDAASLRRVVWTFCRTRLI
LSIVCLMITQLAGFSGPAFVVKHLLEYTQDTESNLQYSLLLVLGLLLTEIVRSWSLALTW
ALNYRTGVRLRGAILTMAFKKILKLKNIKEKSVGELINLCSNDGQRMFEAAAVGSLLAGG
PVIAILGMVYNVIILGPTGFLGSAVFILFYPAMMFVSRITAYFRRKCVTITDDRVQKMNE
VLTYIKFIKMYAWVKAFSQSVQKIREDERRMLEKAGYFQSITVGVAPIVMVIASVVTFSV
HMTLGFDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVAVDRFKSLFLMEEVHMIK
KKPASPHLTIEMKNATLAWDSSHSSIQNSPKLTPKTKKDKRAARGKKEKVRQLQRTEHQA
VLAEQKGHLLLDSDERPSPEEEEGKHIHLGSLRLQRTLYNIDLEIEEGKLVGICGSVGSG
KTSLISSILGQMTLLEGSIAVSGTFAYVAQQAWILNATLRDNILFGKEFDEERYNSVLNC
CCLRPDLAILPHSDLTEIGERGANLSGGQRQRISLARALYSDRDIYILDDPLSALDAHVG
NHIFNSAIQKHLKSKTVLFITHQLQYLADCDEVIFMKEGCITERGTHEELMNLNGDYATI
FNNLLLGETPPVEINSKKETSGSQKKTQEKGPKTGSVKKEKAVKPEEGQLVQMEEKGQGS
VPWSVYGVYIQAAGGPLAFLVILSLFMLNVGSTAFSNWWLSYWIKQGSGNTTVTQENRTS
VSNSMKDNPLMHYYASIYALSMAVMLILKAVRGVVFVKGTLRASSRLHDELFRRILRSPM
KFFDTTPTGRILNRFSKDMDEVDVRLPFQAEMFIQNVILVFFCVGMIAGVFPWFLVAVGP
LVILFSILHIVSRVLIRELKRLDNITQSPFLSHITSSIQGLATIHAYNKGQEFLHRYQEL
LDNNQSPFFLFTCAMRWLAVRLDLISIALITTTGLMIVLMHGQIPPAYAGLAISYAVQLT
GLFQFTVRLASETEARFTSVERIDHYIKTLSLEAPARIKNKAPSPDWPQEGEITFENAEM
RYQENLPLVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELCGGCIKIDGVRISD
IGLADLRSKLSIIPQEPVLFSGTVRSNLDPFNQYTEDQIWDALERTHMKECIAQLPLKLE
SEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREAFADCT
MLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRFYAMFAAAENKIAVKG |
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| NT seq |
4314 nt +upstreamnt +downstreamnt
atgaaggacattgacataggaaaagaatacatcatccccagccctggttatagaaatgtg
cgggagagaaccagcaattcagggcagcaccgagaccgtgaggactccaagtacaagaga
actcaaccgttggattgccaggatgccttggaaacagcagcccgagcggaaggcctttcc
ctggacccctccatgcattctcagctcagaatcctggatgaggaacatcccaagggaaag
taccatcatagcttaagtgttctgaagcccatccggaccacttccaaacaccagcaccca
gtggacaatgctgggctcttctcctgtatgactttttcttggctttctcctctggctcgc
aaagcccacaagaagggggagctcttaatggaggatgtgtggtctttgtcgaagcatgag
tcttctgaggtgaactgcagaagactagagagactgtggcaagaagagctgaatgaagct
gggcccgacgctgcttccctccggagggttgtgtggaccttctgccgcaccaggctcatc
ctctccatcgtgtgcctgatgatcacgcagctggcaggcttcagtggaccagccttcgtg
gtgaaacacctcctggagtacacccaggacacagagtctaacctccagtacagcttgctg
ctagtcctgggcctcctcctgacagaaatcgtgcgttcttggtcacttgcactgacatgg
gcgttgaattaccgaactggggtacgcttgcggggagccatcctaaccatggcgtttaag
aagatccttaagctgaagaacattaaggagaagtctgtgggtgagctcatcaacctgtgc
tcaaacgacgggcagaggatgtttgaggcagctgctgttggcagcttgctggctggagga
cctgttattgccatcttgggcatggtttataatgtaattattctgggaccaacaggcttc
ctgggatcagctgtttttatcctcttttatcctgcaatgatgtttgtttcacggatcact
gcatatttcaggagaaaatgtgtgaccatcacagatgaccgtgtccagaagatgaatgaa
gttctcacctatattaaatttattaaaatgtatgcctgggtcaaagcattctctcagagt
gtacaaaaaatccgagaggatgagcgtcggatgctggaaaaagctgggtactttcagagc
atcactgtcggcgtggctcctattgtgatggtgatcgccagcgtggtgaccttctctgtt
cacatgacccttggctttgatctgacagcggcccaggctttcacagtggtaactgtcttc
aattccatgacttttgctttgaaagttacaccgttttcagtaaagtccctctcagaagca
tctgtggctgttgacagatttaagagtttgtttctaatggaagaggttcacatgataaag
aaaaaaccagccagccctcacctcacgatagagatgaaaaatgccaccttggcatgggac
tcctcccactccagtatccagaactcacccaagctgacccccaaaacgaaaaaagacaag
agggctgccaggggcaagaaagagaaggtgaggcagctgcagcgcactgagcatcaggcg
gtgctggcagaacagaagggtcacctcctcctggacagtgacgagcggcccagccctgag
gaggaagagggcaagcacatccacctggggagcctccgcctgcagaggacgctctacaac
atcgacttagagatcgaagagggtaaactagttggaatctgtggcagtgtgggaagtgga
aaaacttctctcatttcatccattttaggccagatgacacttctagagggcagcattgca
gtcagtggaaccttcgcttatgtggcccagcaggcctggatcctcaatgccactctgaga
gacaacatcctctttgggaaggaatttgatgaagaaagatacaactccgtgctgaactgc
tgctgcctgaggcctgacctggccatccttccccacagtgatctgacagagattggtgag
cgaggagccaacctgagtggcgggcaacgccagaggatcagccttgcccgggccttgtat
agtgaccgagacatctacatcctggacgaccccctcagtgccttagatgcccacgtgggc
aaccacattttcaacagtgctatccagaagcatctcaagtccaagacggttctgttcatt
acccaccagttacagtacctggctgactgtgatgaagtgatcttcatgaaagagggctgt
attacagaaagaggcactcatgaggaattgatgaatctaaatggtgattacgctactatt
tttaataacctgttgctgggagagacacccccagttgagattaattcaaaaaaggaaacc
agtggttcacagaagaaaacacaagagaagggtcctaaaacaggatcagtaaagaaggag
aaagcagtgaagccagaggaagggcagctcgtgcaaatggaagagaaggggcagggctct
gtgccctggtcagtgtatggtgtctatatccaggctgctgggggccctttggcgttcctg
gtcattctgtcccttttcatgctgaatgtgggcagcaccgctttcagcaactggtggttg
agttactggatcaagcaaggaagtgggaacaccacagtgactcaagaaaacaggacatct
gtgagcaacagcatgaaggataatcctctcatgcactactatgccagcatctatgccctc
tccatggcagtcatgctgatcctgaaagccgttcgcggagtggtctttgtcaagggcaca
ttgcgagcctcctcccggctccatgatgagcttttccgaagaatccttcgaagccctatg
aagttttttgacactacccccacaggaagaattctcaacaggttttccaaagacatggat
gaagtcgacgtgcgcctgccgttccaggccgagatgttcattcagaacgtcatcttggtg
ttcttctgtgttggaatgatcgcaggagttttcccatggttcctcgtggcagtggggccc
cttgtcatcctcttttcaattctgcacattgtctccagggtcctgatccgagagctgaag
cgtctagataatatcacgcagtcacctttcctctcccacatcacatccagcatacagggc
cttgccaccatccacgcctataacaaagggcaggaatttctgcacaggtaccaggagcta
ctggataacaaccagagtcctttcttcctgttcacttgtgcgatgcggtggctggcagta
cggctggacctaatcagcattgccctgatcaccaccactgggctgatgattgttctcatg
catgggcagattcccccggcatatgcagggcttgccatctcctatgctgtgcagttgaca
gggctgttccagtttactgtcagactggcatcggagacagaagctcgcttcacctcagtg
gagaggatcgaccactacatcaagactctatctttggaagcacctgccagaattaagaac
aaggctccgtcccctgactggccccaggaaggagagatcacctttgagaatgcagagatg
aggtaccaagaaaatctccctctggtcctgaagaaagtgtccttcaccatcaaacccaag
gagaagattggcatcgtgggtcgaacaggatcagggaagtcctctctgggcatggccctc
ttccgcctggtggagttgtgtggaggctgcattaagattgatggagtgagaatcagtgac
attggccttgctgacctccggagcaagctctccatcattccccaggagccggtgctgttc
agcggtactgtcagatcaaatttggatcccttcaaccagtacacggaagaccagatctgg
gatgccctagaaaggacacacatgaaagaatgtattgctcagctacctctgaaacttgaa
tctgaagtgatggagaatggggataacttctcagtgggggaacggcagctcttgtgcata
gctagagccttactccgtcactgtaagattctgattctagatgaagccacagctgccatg
gacaccgagacagacttactgatccaagagaccatccgagaagcattcgctgactgcacc
atgctgacgattgcccatcgcctacacacagtcctaggctctgataggattatggtgctg
gcccaggggcaggtggtggagttcgacaccccatccgtccttctttccaacgacagctcc
cggttctatgccatgtttgctgctgcagagaacaagattgccgtcaagggctaa |
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