KEGG   Capra hircus (goat): 102187711
Entry
102187711         CDS       T02910                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
chx  Capra hircus (goat)
Pathway
chx04120  Ubiquitin mediated proteolysis
chx04380  Osteoclast differentiation
chx04630  JAK-STAT signaling pathway
chx04668  TNF signaling pathway
chx04910  Insulin signaling pathway
chx04917  Prolactin signaling pathway
chx04920  Adipocytokine signaling pathway
chx04930  Type II diabetes mellitus
chx04931  Insulin resistance
chx04932  Non-alcoholic fatty liver disease
chx04935  Growth hormone synthesis, secretion and action
chx05160  Hepatitis C
chx05164  Influenza A
chx05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:chx00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    102187711 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    102187711 (SOCS3)
   04668 TNF signaling pathway
    102187711 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102187711 (SOCS3)
   04920 Adipocytokine signaling pathway
    102187711 (SOCS3)
   04917 Prolactin signaling pathway
    102187711 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    102187711 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102187711 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    102187711 (SOCS3)
   05164 Influenza A
    102187711 (SOCS3)
   05168 Herpes simplex virus 1 infection
    102187711 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102187711 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    102187711 (SOCS3)
   04931 Insulin resistance
    102187711 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:chx04121]
    102187711 (SOCS3)
Ubiquitin system [BR:chx04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     102187711 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 102187711
NCBI-ProteinID: XP_017919172
UniProt: A0A452E7D4
LinkDB
Position
19:53046049..53049424
AA seq 229 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSTVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPAAGAPSFSPPPAEPSSSPSSEVPEQPPAQPLPGSPPRRAYYIYSGGEKIPL
VLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 690 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagttccccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttttactggagcaccgtgacgggcggcgaagcgaacttgctgctg
agcgccgagcccgcggggaccttcctcatccgcgacagctcggaccagcgccacttcttc
accctcagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttctctctgcagagcgacccccggagcacgcagcccgtgccccgcttcgactgcgtg
ctcaagctggtgcatcactacatgcccgccgccggcgccccctcgttctccccgcccccc
gctgaaccctcctcctcgccctcctccgaggtgcccgagcagccaccggcccagccgctc
cccgggagcccccccaggagagcctattacatttactcggggggcgagaagatccctctg
gtgttgagccggcccctctcctccaacgtggccactctccaacatctctgtcggaagacc
gtcaacggccacctggactcctacgagaaagtcacccagctgcctgggcccattcgggag
ttcctggaccagtacgatgccccgctttag

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