Cebus imitator (Panamanian white-faced capuchin): 108281443
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Entry
108281443 CDS
T08783
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
cimi
Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi01521
EGFR tyrosine kinase inhibitor resistance
cimi04062
Chemokine signaling pathway
cimi04081
Hormone signaling
cimi04148
Efferocytosis
cimi04151
PI3K-Akt signaling pathway
cimi04217
Necroptosis
cimi04550
Signaling pathways regulating pluripotency of stem cells
cimi04630
JAK-STAT signaling pathway
cimi04658
Th1 and Th2 cell differentiation
cimi04659
Th17 cell differentiation
cimi04725
Cholinergic synapse
cimi04917
Prolactin signaling pathway
cimi04920
Adipocytokine signaling pathway
cimi04933
AGE-RAGE signaling pathway in diabetic complications
cimi04935
Growth hormone synthesis, secretion and action
cimi05140
Leishmaniasis
cimi05145
Toxoplasmosis
cimi05152
Tuberculosis
cimi05161
Hepatitis B
cimi05164
Influenza A
cimi05167
Kaposi sarcoma-associated herpesvirus infection
cimi05168
Herpes simplex virus 1 infection
cimi05200
Pathways in cancer
cimi05207
Chemical carcinogenesis - receptor activation
cimi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cimi05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cimi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
108281443 (JAK2)
04151 PI3K-Akt signaling pathway
108281443 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
108281443 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
108281443 (JAK2)
09143 Cell growth and death
04217 Necroptosis
108281443 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
108281443 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
108281443 (JAK2)
04659 Th17 cell differentiation
108281443 (JAK2)
04062 Chemokine signaling pathway
108281443 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
108281443 (JAK2)
04917 Prolactin signaling pathway
108281443 (JAK2)
04935 Growth hormone synthesis, secretion and action
108281443 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
108281443 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108281443 (JAK2)
05207 Chemical carcinogenesis - receptor activation
108281443 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108281443 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
108281443 (JAK2)
05164 Influenza A
108281443 (JAK2)
05168 Herpes simplex virus 1 infection
108281443 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
108281443 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
108281443 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
108281443 (JAK2)
05140 Leishmaniasis
108281443 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
108281443 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
108281443 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108281443 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cimi01001
]
108281443 (JAK2)
Enzymes [BR:
cimi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
108281443 (JAK2)
Protein kinases [BR:
cimi01001
]
Non-receptor tyrosine kinases
JAK family [OT]
108281443 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
108281443
NCBI-ProteinID:
XP_017352477
Ensembl:
ENSCCAG00000022686
UniProt:
A0A2K5Q1Z3
LinkDB
All DBs
Position
Unknown
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSTSSINQNGDISGNVNSIKQIDPVLQVYLYHSLGKAEADYLTFPSG
EYVAEEICIAASKACGITPLYHNMFALMSETERIWYPPNHVFHVDESIRDNVLYRIRFYF
PHWYCSGNNRTYRHGISRGAEAPLLDDFVMSYLFSQWRHDFVHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQF
SQCKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRMNGVSDVPISPTLQRHNNVNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWA
MHFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNIRMGLSGFSVAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggagggaacatccacatcttctataaat
cagaatggtgatatttctggaaatgtcaattctataaagcaaatagatccggtccttcag
gtgtatctttaccattcccttgggaaagctgaggcagattatctgacatttccatctggg
gaatatgttgcagaagaaatctgtattgctgcttctaaagcttgtggcatcacacctttg
tatcataatatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccat
gtcttccacgtagatgaatcaatcagggataatgtactctacagaataagattttacttt
cctcattggtattgcagcggcaacaacagaacctatcggcatggaatatctcgaggtgct
gaagctcctcttcttgatgattttgtcatgtcttaccttttttctcagtggcggcatgat
tttgtgcatggatggataaaggtacctgtgactcatgaaactcaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagctaaagaaaaggatcaaactccactggccatc
tataattctatcagctacaagacattcttaccaaaatgtattcgagcaaagatccaagat
tatcacattttgacaaggaagcgaataaggtacagatttcgcagatttattcagcagttc
agccaatgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
ctgcagtctgccttctacacagagaaatttgaagtaaaagaacctggaagtggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttgtattgtgatttt
cctaatattattgatgtcagtattaagcaagcaaaccaagagggttcaaatgaaagcaga
gtggtgactatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagg
gaagctttgtctttcgtgtcattaattgatggctattatagattaactgcagatgcacat
cattacctctgtaaagaagtagcacctccaacggtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggactttgccatcagtaaactgaagaaagcaggcaatcagact
ggactgtatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gtcgagcgagaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatgaa
gagtacaacctcagtgggacaaagaagaacttcagtagccttaaagatcttttgaattgt
taccagatggaaactgttcgctcagacaatataattttccagtttactaaatgctgtccc
ccaaagccaaaagataaatcaaaccttctagtcttcagaatgaatggtgtttcggatgtc
ccaatctcaccgacattacagaggcataataacgtgaaccaaatggtgtttcacaaaatt
agaaatgaagatttgatatttaatgaaagccttggccaaggcacttttacaaagattttt
aaaggcatacgaagagaagtaggagactatggccaactgcatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaggcagcaagcatg
atgagccagctttctcacaagcatttggttttaaattatggagtgtgtgtctgcggagag
gagaatattctggttcaggagtttgtaaaatttggatcactagatacatatctgaaaaag
aataaaaattgtataaatatattatggaaacttgaagttgctaaacagttggcatgggcc
atgcattttctagaagaaaagacccttattcatgggaatgtgtgtgccaaaaatattcta
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgaccct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatttaaatttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataaacccttaagtgctctggattctcaa
agaaagctgcaattttatgaagataggcaccagcttcctgcaccaaagtgggcagaatta
gcaaaccttataaataattgtatggattacgaaccagatttcaggccttccttcagagcc
atcatacgagatcttaacagtttgtttacaccagattatgaactattaacagaaaatgac
atgttaccaaatataaggatgggtctttcagggttttctgttgcttttgaagacagggat
cctacacagtttgaagagagacatttgaaatttctacagcaacttggcaagggtaatttt
gggagtgtggagatgtgccgatatgaccctctacaggacaacactggggaggtggtggct
gtaaaaaagcttcagcatagtactgaggagcacctgagagactttgaaagggaaattgaa
atcttgaaatcactgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggtcggcgtaatctaaaattaattatggaatatttaccatatggaagtttacgagactat
cttcaaaaacataaagaacggatagatcacaaaaaacttctgcagtacacatctcagatc
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaaga
aatatattggtggagaatgagaacagagttaaaattggagattttgggttaaccaaagtc
ttgccccaagacaaagaatactataaagtaaaagaacctggtgaaagtcccatattctgg
tatgctccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagtttt
ggagtggttctgtatgaacttttcacatacattgagaagagtaaaagtccaccagcggaa
tttatgcgtatgattggcaatgacaaacaaggacagatgatcgtgttccatttgatagaa
ctgttgaagaataatggaagattaccaagaccagatggatgcccagatgagatttatttg
atcatgacagaatgctggaacaataatgtaaatcaacgcccctcctttagggatctagct
cttcgagtggatcaaataagggataacatggctggataa
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