KEGG   Cebus imitator (Panamanian white-faced capuchin): 108282680
Entry
108282680         CDS       T08783                                 
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 1-like
  KO
K04368  mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
Organism
cimi  Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi01521  EGFR tyrosine kinase inhibitor resistance
cimi01522  Endocrine resistance
cimi04010  MAPK signaling pathway
cimi04012  ErbB signaling pathway
cimi04014  Ras signaling pathway
cimi04015  Rap1 signaling pathway
cimi04022  cGMP-PKG signaling pathway
cimi04024  cAMP signaling pathway
cimi04062  Chemokine signaling pathway
cimi04066  HIF-1 signaling pathway
cimi04068  FoxO signaling pathway
cimi04071  Sphingolipid signaling pathway
cimi04072  Phospholipase D signaling pathway
cimi04114  Oocyte meiosis
cimi04140  Autophagy - animal
cimi04148  Efferocytosis
cimi04150  mTOR signaling pathway
cimi04151  PI3K-Akt signaling pathway
cimi04210  Apoptosis
cimi04218  Cellular senescence
cimi04270  Vascular smooth muscle contraction
cimi04370  VEGF signaling pathway
cimi04371  Apelin signaling pathway
cimi04380  Osteoclast differentiation
cimi04510  Focal adhesion
cimi04540  Gap junction
cimi04550  Signaling pathways regulating pluripotency of stem cells
cimi04613  Neutrophil extracellular trap formation
cimi04620  Toll-like receptor signaling pathway
cimi04650  Natural killer cell mediated cytotoxicity
cimi04660  T cell receptor signaling pathway
cimi04662  B cell receptor signaling pathway
cimi04664  Fc epsilon RI signaling pathway
cimi04666  Fc gamma R-mediated phagocytosis
cimi04668  TNF signaling pathway
cimi04720  Long-term potentiation
cimi04722  Neurotrophin signaling pathway
cimi04725  Cholinergic synapse
cimi04726  Serotonergic synapse
cimi04730  Long-term depression
cimi04810  Regulation of actin cytoskeleton
cimi04910  Insulin signaling pathway
cimi04912  GnRH signaling pathway
cimi04914  Progesterone-mediated oocyte maturation
cimi04915  Estrogen signaling pathway
cimi04916  Melanogenesis
cimi04917  Prolactin signaling pathway
cimi04919  Thyroid hormone signaling pathway
cimi04921  Oxytocin signaling pathway
cimi04926  Relaxin signaling pathway
cimi04928  Parathyroid hormone synthesis, secretion and action
cimi04929  GnRH secretion
cimi04934  Cushing syndrome
cimi04935  Growth hormone synthesis, secretion and action
cimi05010  Alzheimer disease
cimi05022  Pathways of neurodegeneration - multiple diseases
cimi05034  Alcoholism
cimi05132  Salmonella infection
cimi05135  Yersinia infection
cimi05160  Hepatitis C
cimi05161  Hepatitis B
cimi05163  Human cytomegalovirus infection
cimi05164  Influenza A
cimi05165  Human papillomavirus infection
cimi05166  Human T-cell leukemia virus 1 infection
cimi05167  Kaposi sarcoma-associated herpesvirus infection
cimi05170  Human immunodeficiency virus 1 infection
cimi05200  Pathways in cancer
cimi05205  Proteoglycans in cancer
cimi05206  MicroRNAs in cancer
cimi05207  Chemical carcinogenesis - receptor activation
cimi05208  Chemical carcinogenesis - reactive oxygen species
cimi05210  Colorectal cancer
cimi05211  Renal cell carcinoma
cimi05212  Pancreatic cancer
cimi05213  Endometrial cancer
cimi05214  Glioma
cimi05215  Prostate cancer
cimi05216  Thyroid cancer
cimi05218  Melanoma
cimi05219  Bladder cancer
cimi05220  Chronic myeloid leukemia
cimi05221  Acute myeloid leukemia
cimi05223  Non-small cell lung cancer
cimi05224  Breast cancer
cimi05225  Hepatocellular carcinoma
cimi05226  Gastric cancer
cimi05230  Central carbon metabolism in cancer
cimi05231  Choline metabolism in cancer
cimi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:cimi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108282680
   04012 ErbB signaling pathway
    108282680
   04014 Ras signaling pathway
    108282680
   04015 Rap1 signaling pathway
    108282680
   04370 VEGF signaling pathway
    108282680
   04371 Apelin signaling pathway
    108282680
   04668 TNF signaling pathway
    108282680
   04066 HIF-1 signaling pathway
    108282680
   04068 FoxO signaling pathway
    108282680
   04072 Phospholipase D signaling pathway
    108282680
   04071 Sphingolipid signaling pathway
    108282680
   04024 cAMP signaling pathway
    108282680
   04022 cGMP-PKG signaling pathway
    108282680
   04151 PI3K-Akt signaling pathway
    108282680
   04150 mTOR signaling pathway
    108282680
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    108282680
   04148 Efferocytosis
    108282680
  09143 Cell growth and death
   04114 Oocyte meiosis
    108282680
   04210 Apoptosis
    108282680
   04218 Cellular senescence
    108282680
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108282680
   04540 Gap junction
    108282680
   04550 Signaling pathways regulating pluripotency of stem cells
    108282680
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    108282680
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    108282680
   04620 Toll-like receptor signaling pathway
    108282680
   04650 Natural killer cell mediated cytotoxicity
    108282680
   04660 T cell receptor signaling pathway
    108282680
   04662 B cell receptor signaling pathway
    108282680
   04664 Fc epsilon RI signaling pathway
    108282680
   04666 Fc gamma R-mediated phagocytosis
    108282680
   04062 Chemokine signaling pathway
    108282680
  09152 Endocrine system
   04910 Insulin signaling pathway
    108282680
   04929 GnRH secretion
    108282680
   04912 GnRH signaling pathway
    108282680
   04915 Estrogen signaling pathway
    108282680
   04914 Progesterone-mediated oocyte maturation
    108282680
   04917 Prolactin signaling pathway
    108282680
   04921 Oxytocin signaling pathway
    108282680
   04926 Relaxin signaling pathway
    108282680
   04935 Growth hormone synthesis, secretion and action
    108282680
   04919 Thyroid hormone signaling pathway
    108282680
   04928 Parathyroid hormone synthesis, secretion and action
    108282680
   04916 Melanogenesis
    108282680
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    108282680
  09156 Nervous system
   04725 Cholinergic synapse
    108282680
   04726 Serotonergic synapse
    108282680
   04720 Long-term potentiation
    108282680
   04730 Long-term depression
    108282680
   04722 Neurotrophin signaling pathway
    108282680
  09158 Development and regeneration
   04380 Osteoclast differentiation
    108282680
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108282680
   05206 MicroRNAs in cancer
    108282680
   05205 Proteoglycans in cancer
    108282680
   05207 Chemical carcinogenesis - receptor activation
    108282680
   05208 Chemical carcinogenesis - reactive oxygen species
    108282680
   05230 Central carbon metabolism in cancer
    108282680
   05231 Choline metabolism in cancer
    108282680
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108282680
  09162 Cancer: specific types
   05210 Colorectal cancer
    108282680
   05212 Pancreatic cancer
    108282680
   05225 Hepatocellular carcinoma
    108282680
   05226 Gastric cancer
    108282680
   05214 Glioma
    108282680
   05216 Thyroid cancer
    108282680
   05221 Acute myeloid leukemia
    108282680
   05220 Chronic myeloid leukemia
    108282680
   05218 Melanoma
    108282680
   05211 Renal cell carcinoma
    108282680
   05219 Bladder cancer
    108282680
   05215 Prostate cancer
    108282680
   05213 Endometrial cancer
    108282680
   05224 Breast cancer
    108282680
   05223 Non-small cell lung cancer
    108282680
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108282680
   05170 Human immunodeficiency virus 1 infection
    108282680
   05161 Hepatitis B
    108282680
   05160 Hepatitis C
    108282680
   05164 Influenza A
    108282680
   05163 Human cytomegalovirus infection
    108282680
   05167 Kaposi sarcoma-associated herpesvirus infection
    108282680
   05165 Human papillomavirus infection
    108282680
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108282680
   05135 Yersinia infection
    108282680
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108282680
   05022 Pathways of neurodegeneration - multiple diseases
    108282680
  09165 Substance dependence
   05034 Alcoholism
    108282680
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    108282680
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108282680
   01522 Endocrine resistance
    108282680
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cimi01001]
    108282680
Enzymes [BR:cimi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     108282680
Protein kinases [BR:cimi01001]
 Serine/threonine kinases: STE group
  STE7 family
   108282680
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like
Other DBs
NCBI-GeneID: 108282680
NCBI-ProteinID: XP_017354162
Ensembl: ENSCCAG00000024279
LinkDB
Position
Unknown
AA seq 245 aa
MGDRSVVLGLTVRAASVWNADPSLPQSTCVSSLLFYFLFPADVKPSNILVNSRGEIKLCD
FGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDA
KELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSG
VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPT
HAAGV
NT seq 738 nt   +upstreamnt  +downstreamnt
atgggggataggagtgttgtcctgggactcacagtcagggctgcttctgtgtggaatgct
gatccttctcttccccagtctacctgtgtcagttcccttcttttctattttctttttcct
gcagatgtcaagccctccaacatcctagtcaactcccgtggggagatcaagctctgtgac
tttggggtcagcgggcagctcatcgactccatggccaactccttcgtgggcacaaggtcc
tacatgtcgccagaaaggctccaggggactcattactctgtgcagtcggacatctggagc
atgggactctctctggtagagatggcggttgggaggtatcccatccctcctccagatgcc
aaggagctggagctgatgtttgggtgccaggtggagggagatgcggctgagaccccaccc
aggccaaggacccctgggaggccccttagctcatatggaatggacagccgacctcccatg
gcaatttttgagttgttggattacatagtcaatgagcctcctccaaaactgcccagtgga
gtgttcagcctggaatttcaagattttgtgaataaatgcttaataaaaaacccggcagag
agagcagatttgaagcaactcatggttcatgcttttatcaagagatctgacgctgaggaa
gtggattttgcaggttggctctgctccaccattggccttaaccagcccagcacgccaacc
catgctgctggcgtctaa

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