Cebus imitator (Panamanian white-faced capuchin): 108284634
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Entry
108284634 CDS
T08783
Symbol
RAF1
Name
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X1
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
cimi
Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi01521
EGFR tyrosine kinase inhibitor resistance
cimi01522
Endocrine resistance
cimi04010
MAPK signaling pathway
cimi04012
ErbB signaling pathway
cimi04014
Ras signaling pathway
cimi04015
Rap1 signaling pathway
cimi04022
cGMP-PKG signaling pathway
cimi04024
cAMP signaling pathway
cimi04062
Chemokine signaling pathway
cimi04068
FoxO signaling pathway
cimi04071
Sphingolipid signaling pathway
cimi04072
Phospholipase D signaling pathway
cimi04140
Autophagy - animal
cimi04150
mTOR signaling pathway
cimi04151
PI3K-Akt signaling pathway
cimi04210
Apoptosis
cimi04218
Cellular senescence
cimi04270
Vascular smooth muscle contraction
cimi04360
Axon guidance
cimi04370
VEGF signaling pathway
cimi04371
Apelin signaling pathway
cimi04510
Focal adhesion
cimi04540
Gap junction
cimi04550
Signaling pathways regulating pluripotency of stem cells
cimi04613
Neutrophil extracellular trap formation
cimi04625
C-type lectin receptor signaling pathway
cimi04630
JAK-STAT signaling pathway
cimi04650
Natural killer cell mediated cytotoxicity
cimi04660
T cell receptor signaling pathway
cimi04662
B cell receptor signaling pathway
cimi04664
Fc epsilon RI signaling pathway
cimi04666
Fc gamma R-mediated phagocytosis
cimi04720
Long-term potentiation
cimi04722
Neurotrophin signaling pathway
cimi04726
Serotonergic synapse
cimi04730
Long-term depression
cimi04810
Regulation of actin cytoskeleton
cimi04910
Insulin signaling pathway
cimi04912
GnRH signaling pathway
cimi04914
Progesterone-mediated oocyte maturation
cimi04915
Estrogen signaling pathway
cimi04916
Melanogenesis
cimi04917
Prolactin signaling pathway
cimi04919
Thyroid hormone signaling pathway
cimi04921
Oxytocin signaling pathway
cimi04926
Relaxin signaling pathway
cimi04928
Parathyroid hormone synthesis, secretion and action
cimi04929
GnRH secretion
cimi04935
Growth hormone synthesis, secretion and action
cimi05010
Alzheimer disease
cimi05022
Pathways of neurodegeneration - multiple diseases
cimi05034
Alcoholism
cimi05132
Salmonella infection
cimi05152
Tuberculosis
cimi05160
Hepatitis C
cimi05161
Hepatitis B
cimi05163
Human cytomegalovirus infection
cimi05164
Influenza A
cimi05165
Human papillomavirus infection
cimi05167
Kaposi sarcoma-associated herpesvirus infection
cimi05170
Human immunodeficiency virus 1 infection
cimi05200
Pathways in cancer
cimi05205
Proteoglycans in cancer
cimi05206
MicroRNAs in cancer
cimi05207
Chemical carcinogenesis - receptor activation
cimi05208
Chemical carcinogenesis - reactive oxygen species
cimi05210
Colorectal cancer
cimi05211
Renal cell carcinoma
cimi05212
Pancreatic cancer
cimi05213
Endometrial cancer
cimi05214
Glioma
cimi05215
Prostate cancer
cimi05218
Melanoma
cimi05219
Bladder cancer
cimi05220
Chronic myeloid leukemia
cimi05221
Acute myeloid leukemia
cimi05223
Non-small cell lung cancer
cimi05224
Breast cancer
cimi05225
Hepatocellular carcinoma
cimi05226
Gastric cancer
cimi05230
Central carbon metabolism in cancer
cimi05231
Choline metabolism in cancer
cimi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
cimi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
108284634 (RAF1)
04015 Rap1 signaling pathway
108284634 (RAF1)
04630 JAK-STAT signaling pathway
108284634 (RAF1)
04068 FoxO signaling pathway
108284634 (RAF1)
04072 Phospholipase D signaling pathway
108284634 (RAF1)
04071 Sphingolipid signaling pathway
108284634 (RAF1)
04024 cAMP signaling pathway
108284634 (RAF1)
04022 cGMP-PKG signaling pathway
108284634 (RAF1)
04151 PI3K-Akt signaling pathway
108284634 (RAF1)
04150 mTOR signaling pathway
108284634 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
108284634 (RAF1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
108284634 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
108284634 (RAF1)
04650 Natural killer cell mediated cytotoxicity
108284634 (RAF1)
04660 T cell receptor signaling pathway
108284634 (RAF1)
04662 B cell receptor signaling pathway
108284634 (RAF1)
04664 Fc epsilon RI signaling pathway
108284634 (RAF1)
04666 Fc gamma R-mediated phagocytosis
108284634 (RAF1)
04062 Chemokine signaling pathway
108284634 (RAF1)
09152 Endocrine system
04929 GnRH secretion
108284634 (RAF1)
04915 Estrogen signaling pathway
108284634 (RAF1)
04917 Prolactin signaling pathway
108284634 (RAF1)
04921 Oxytocin signaling pathway
108284634 (RAF1)
04926 Relaxin signaling pathway
108284634 (RAF1)
04935 Growth hormone synthesis, secretion and action
108284634 (RAF1)
04919 Thyroid hormone signaling pathway
108284634 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
108284634 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
108284634 (RAF1)
04720 Long-term potentiation
108284634 (RAF1)
04730 Long-term depression
108284634 (RAF1)
04722 Neurotrophin signaling pathway
108284634 (RAF1)
09158 Development and regeneration
04360 Axon guidance
108284634 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108284634 (RAF1)
05206 MicroRNAs in cancer
108284634 (RAF1)
05205 Proteoglycans in cancer
108284634 (RAF1)
05207 Chemical carcinogenesis - receptor activation
108284634 (RAF1)
05208 Chemical carcinogenesis - reactive oxygen species
108284634 (RAF1)
05230 Central carbon metabolism in cancer
108284634 (RAF1)
05231 Choline metabolism in cancer
108284634 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108284634 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
108284634 (RAF1)
05212 Pancreatic cancer
108284634 (RAF1)
05225 Hepatocellular carcinoma
108284634 (RAF1)
05226 Gastric cancer
108284634 (RAF1)
05214 Glioma
108284634 (RAF1)
05221 Acute myeloid leukemia
108284634 (RAF1)
05220 Chronic myeloid leukemia
108284634 (RAF1)
05218 Melanoma
108284634 (RAF1)
05211 Renal cell carcinoma
108284634 (RAF1)
05219 Bladder cancer
108284634 (RAF1)
05215 Prostate cancer
108284634 (RAF1)
05213 Endometrial cancer
108284634 (RAF1)
05224 Breast cancer
108284634 (RAF1)
05223 Non-small cell lung cancer
108284634 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
108284634 (RAF1)
05161 Hepatitis B
108284634 (RAF1)
05160 Hepatitis C
108284634 (RAF1)
05164 Influenza A
108284634 (RAF1)
05163 Human cytomegalovirus infection
108284634 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
108284634 (RAF1)
05165 Human papillomavirus infection
108284634 (RAF1)
09171 Infectious disease: bacterial
05152 Tuberculosis
108284634 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
108284634 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
108284634 (RAF1)
09165 Substance dependence
05034 Alcoholism
108284634 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108284634 (RAF1)
01522 Endocrine resistance
108284634 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cimi01001
]
108284634 (RAF1)
Enzymes [BR:
cimi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
108284634 (RAF1)
Protein kinases [BR:
cimi01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
108284634 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RBD
C1_1
Kinase-like
ABC1
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
108284634
NCBI-ProteinID:
XP_017356925
Ensembl:
ENSCCAG00000023070
LinkDB
All DBs
Position
Unknown
AA seq
668 aa
AA seq
DB search
MEHIQGAWKTISNGFGLKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLQEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTTGDSGVPALPSLTMRRMRESVTRIPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIENNNLNASPRAWSRRFCLRGRDA
IRSHSESASPSALSSSPNNLSPTGWSQPKTPMPAQRERAPGSGTQEKNKIRPRGQRDSSY
YWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKT
RHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLH
AKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQ
DNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKA
MKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLT
TSPRLPVF
NT seq
2007 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggagcttggaagacgatcagcaatggttttggactcaaagatgcc
gtgtttgatggctccagctgcatctctcctacaatagttcagcagtttggctatcagcgc
cgggcatcagatgatggcaaactcacagatccttcgaagacaagcaacactatccgtgtt
ttcttgccgaacaagcaaagaacagtggtcaatgtgcgaaatggaatgagcttgcatgac
tgccttatgaaagcactgaaggtgagaggcctgcaaccagagtgctgtgcagtgttcaga
cttctccaagaacataaaggtaaaaaagcacgcttagattggaatactgatgctgcctct
ttgattggagaagaacttcaagtagatttcctggatcatgttcccctcacaacacacaac
tttgctcggaagacgttcctgaagcttgccttctgtgacatctgtcagaaattcctgctc
aatggatttcgatgtcagacttgtggctacaaatttcatgagcactgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacaactcttattgtttccaaattccact
actggtgatagtggagtcccagcactaccttctttgactatgcgtcgtatgcgagagtct
gttacccggatacctgttagttctcagcacagatattctacacctcacgccttcaccttt
aacacctccagtccctcatctgaaggttccctctcccagaggcagaggtcgacgtctaca
cctaatgtccacatggtcagcaccaccctgcctgtggacagcaggatgattgagaataac
aacctgaatgcttctcccagggcgtggtccagacgattttgtttgaggggaagagatgca
attcgaagtcacagcgaatcagcctcaccttcagccctgtccagtagccccaacaatctg
agcccaacaggctggtcacagcccaaaacccccatgccagcgcaaagggagcgggcacca
ggatctggaacccaggagaaaaacaaaattaggcctcgtggacagagagattcaagctat
tactgggaaatagaagccagtgaagtgatgctctccactcggattgggtcaggctctttt
ggaactgtttataagggcaaatggcacggagatgttgcagtgaagatcctaaaggttgtc
gacccaaccccagagcagttccaggccttcaggaatgaggtggctgttttgcgcaaaaca
cggcatgtgaacattctgcttttcatggggtacatgacaaaggacaacctggcaattgtg
acccagtggtgcgagggcagcagcctctacaaacacctgcatgtccaggagaccaagttt
cagatgttccagctaattgacattgcccggcagacggctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggccta
acagtgaaaattggagattttggtttggcaacagtaaagtcacgctggagtggttctcag
caagttgaacaacctactggctctgttctgtggatggctccagaggtgatccgaatgcag
gataacaacccattcagcttccagtcagatgtctactcctatggcatcgtattgtatgag
ctgatgacaggggagcttccttactctcacattaacaaccgagatcagatcatcttcatg
gtgggccgagggtatgcctccccagatcttagtaagctatataagaactgccccaaagca
atgaagaggctggtagctgactgtgtcaagaaagtaaaggaagagaggcctctttttccc
cagatcctgtcttccattgagctactccagcactctctaccgaagatcaaccggagcgct
tccgagccatccttgcatcgggcagcccacactgaggatatcaatgcttgcacgctgacc
acgtccccgaggctgcctgtcttctag
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integrated database retrieval system