KEGG   Cebus imitator (Panamanian white-faced capuchin): 108284956
Entry
108284956         CDS       T08783                                 
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
  KO
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
Organism
cimi  Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi00140  Steroid hormone biosynthesis
cimi01100  Metabolic pathways
cimi05215  Prostate cancer
Module
cimi_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:cimi00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    108284956 (SRD5A2)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    108284956 (SRD5A2)
Enzymes [BR:cimi01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     108284956 (SRD5A2)
SSDB
Motif
Pfam: Steroid_dh DUF1295 DUF6832
Other DBs
NCBI-GeneID: 108284956
NCBI-ProteinID: XP_017357422
Ensembl: ENSCCAG00000030143
UniProt: A0A2K5R970
LinkDB
Position
Unknown
AA seq 233 aa
MGVQCQQSPVLVGSATLAAFGALTLYFAKPASYGKHTEILTPAATSLSARAAWFLQELPS
FVVPAGILARQPLSLFGPPGPVLLGFFCLHYFYRTFVYPLLSRGRPYPVLLIFQGIAFCA
GNGFLQGYYLIYCAEYPDEWYTDIRFSLGVFLFLLGMGINIHSDYILCQLRKPGEIIYRI
PQGGMFTYVSGANFFGEIIEWIGFALATWSLPALAFAFFSLCFLGLRAFHHHR
NT seq 702 nt   +upstreamnt  +downstreamnt
atgggggttcagtgccaacagagcccagtgctggtaggcagcgccactttggccgccttc
ggggcactgaccttgtacttcgcgaagcccgccagctacgggaagcacacggagatcctg
acgcccgcggctaccagcctgtccgcccgagccgcctggttcctgcaggagctgccctcc
ttcgtggtgcccgcggggatcctcgcccgtcagccgctctcccttttcgggccacctggg
ccggtgcttctgggcttcttctgcttacactacttctacaggacatttgtctacccactg
ctcagtcgagggaggccttatccagttctactcattttccaaggcattgccttctgtgct
ggaaatggattccttcaaggctactacctgatttactgtgctgaataccctgatgagtgg
tacacagacatacgatttagcttgggtgtcttcttatttcttttgggaatgggaatcaac
attcatagtgactacatattgtgccagctcaggaagcctggagaaatcatctataggatt
ccacaaggtggcatgtttacgtatgtttctggagccaatttcttcggtgagatcattgaa
tggatcggctttgccctggccacttggtccctcccagcacttgcatttgcatttttctca
ctttgtttccttgggctgcgagcttttcaccaccataggtaa

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