KEGG   Cebus imitator (Panamanian white-faced capuchin): 108285792
Entry
108285792         CDS       T08783                                 
Symbol
AKT2
Name
(RefSeq) RAC-beta serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
cimi  Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi01521  EGFR tyrosine kinase inhibitor resistance
cimi01522  Endocrine resistance
cimi01524  Platinum drug resistance
cimi04010  MAPK signaling pathway
cimi04012  ErbB signaling pathway
cimi04014  Ras signaling pathway
cimi04015  Rap1 signaling pathway
cimi04022  cGMP-PKG signaling pathway
cimi04024  cAMP signaling pathway
cimi04062  Chemokine signaling pathway
cimi04066  HIF-1 signaling pathway
cimi04068  FoxO signaling pathway
cimi04071  Sphingolipid signaling pathway
cimi04072  Phospholipase D signaling pathway
cimi04140  Autophagy - animal
cimi04150  mTOR signaling pathway
cimi04151  PI3K-Akt signaling pathway
cimi04152  AMPK signaling pathway
cimi04210  Apoptosis
cimi04211  Longevity regulating pathway
cimi04213  Longevity regulating pathway - multiple species
cimi04218  Cellular senescence
cimi04261  Adrenergic signaling in cardiomyocytes
cimi04370  VEGF signaling pathway
cimi04371  Apelin signaling pathway
cimi04380  Osteoclast differentiation
cimi04510  Focal adhesion
cimi04517  IgSF CAM signaling
cimi04518  Integrin signaling
cimi04550  Signaling pathways regulating pluripotency of stem cells
cimi04611  Platelet activation
cimi04613  Neutrophil extracellular trap formation
cimi04620  Toll-like receptor signaling pathway
cimi04625  C-type lectin receptor signaling pathway
cimi04630  JAK-STAT signaling pathway
cimi04660  T cell receptor signaling pathway
cimi04662  B cell receptor signaling pathway
cimi04664  Fc epsilon RI signaling pathway
cimi04666  Fc gamma R-mediated phagosome formation
cimi04668  TNF signaling pathway
cimi04722  Neurotrophin signaling pathway
cimi04725  Cholinergic synapse
cimi04728  Dopaminergic synapse
cimi04810  Regulation of actin cytoskeleton
cimi04910  Insulin signaling pathway
cimi04914  Progesterone-mediated oocyte maturation
cimi04915  Estrogen signaling pathway
cimi04917  Prolactin signaling pathway
cimi04919  Thyroid hormone signaling pathway
cimi04920  Adipocytokine signaling pathway
cimi04922  Glucagon signaling pathway
cimi04923  Regulation of lipolysis in adipocytes
cimi04926  Relaxin signaling pathway
cimi04929  GnRH secretion
cimi04931  Insulin resistance
cimi04932  Non-alcoholic fatty liver disease
cimi04933  AGE-RAGE signaling pathway in diabetic complications
cimi04935  Growth hormone synthesis, secretion and action
cimi04936  Alcoholic liver disease
cimi04973  Carbohydrate digestion and absorption
cimi05010  Alzheimer disease
cimi05017  Spinocerebellar ataxia
cimi05132  Salmonella infection
cimi05135  Yersinia infection
cimi05142  Chagas disease
cimi05145  Toxoplasmosis
cimi05152  Tuberculosis
cimi05160  Hepatitis C
cimi05161  Hepatitis B
cimi05162  Measles
cimi05163  Human cytomegalovirus infection
cimi05164  Influenza A
cimi05165  Human papillomavirus infection
cimi05166  Human T-cell leukemia virus 1 infection
cimi05167  Kaposi sarcoma-associated herpesvirus infection
cimi05168  Herpes simplex virus 1 infection
cimi05169  Epstein-Barr virus infection
cimi05170  Human immunodeficiency virus 1 infection
cimi05200  Pathways in cancer
cimi05205  Proteoglycans in cancer
cimi05207  Chemical carcinogenesis - receptor activation
cimi05208  Chemical carcinogenesis - reactive oxygen species
cimi05210  Colorectal cancer
cimi05211  Renal cell carcinoma
cimi05212  Pancreatic cancer
cimi05213  Endometrial cancer
cimi05214  Glioma
cimi05215  Prostate cancer
cimi05218  Melanoma
cimi05220  Chronic myeloid leukemia
cimi05221  Acute myeloid leukemia
cimi05222  Small cell lung cancer
cimi05223  Non-small cell lung cancer
cimi05224  Breast cancer
cimi05225  Hepatocellular carcinoma
cimi05226  Gastric cancer
cimi05230  Central carbon metabolism in cancer
cimi05231  Choline metabolism in cancer
cimi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cimi05415  Diabetic cardiomyopathy
cimi05417  Lipid and atherosclerosis
cimi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cimi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108285792 (AKT2)
   04012 ErbB signaling pathway
    108285792 (AKT2)
   04014 Ras signaling pathway
    108285792 (AKT2)
   04015 Rap1 signaling pathway
    108285792 (AKT2)
   04370 VEGF signaling pathway
    108285792 (AKT2)
   04371 Apelin signaling pathway
    108285792 (AKT2)
   04630 JAK-STAT signaling pathway
    108285792 (AKT2)
   04668 TNF signaling pathway
    108285792 (AKT2)
   04066 HIF-1 signaling pathway
    108285792 (AKT2)
   04068 FoxO signaling pathway
    108285792 (AKT2)
   04072 Phospholipase D signaling pathway
    108285792 (AKT2)
   04071 Sphingolipid signaling pathway
    108285792 (AKT2)
   04024 cAMP signaling pathway
    108285792 (AKT2)
   04022 cGMP-PKG signaling pathway
    108285792 (AKT2)
   04151 PI3K-Akt signaling pathway
    108285792 (AKT2)
   04152 AMPK signaling pathway
    108285792 (AKT2)
   04150 mTOR signaling pathway
    108285792 (AKT2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    108285792 (AKT2)
   04518 Integrin signaling
    108285792 (AKT2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    108285792 (AKT2)
  09143 Cell growth and death
   04210 Apoptosis
    108285792 (AKT2)
   04218 Cellular senescence
    108285792 (AKT2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108285792 (AKT2)
   04550 Signaling pathways regulating pluripotency of stem cells
    108285792 (AKT2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    108285792 (AKT2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    108285792 (AKT2)
   04613 Neutrophil extracellular trap formation
    108285792 (AKT2)
   04620 Toll-like receptor signaling pathway
    108285792 (AKT2)
   04625 C-type lectin receptor signaling pathway
    108285792 (AKT2)
   04660 T cell receptor signaling pathway
    108285792 (AKT2)
   04662 B cell receptor signaling pathway
    108285792 (AKT2)
   04664 Fc epsilon RI signaling pathway
    108285792 (AKT2)
   04666 Fc gamma R-mediated phagosome formation
    108285792 (AKT2)
   04062 Chemokine signaling pathway
    108285792 (AKT2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    108285792 (AKT2)
   04922 Glucagon signaling pathway
    108285792 (AKT2)
   04923 Regulation of lipolysis in adipocytes
    108285792 (AKT2)
   04920 Adipocytokine signaling pathway
    108285792 (AKT2)
   04929 GnRH secretion
    108285792 (AKT2)
   04915 Estrogen signaling pathway
    108285792 (AKT2)
   04914 Progesterone-mediated oocyte maturation
    108285792 (AKT2)
   04917 Prolactin signaling pathway
    108285792 (AKT2)
   04926 Relaxin signaling pathway
    108285792 (AKT2)
   04935 Growth hormone synthesis, secretion and action
    108285792 (AKT2)
   04919 Thyroid hormone signaling pathway
    108285792 (AKT2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108285792 (AKT2)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    108285792 (AKT2)
  09156 Nervous system
   04725 Cholinergic synapse
    108285792 (AKT2)
   04728 Dopaminergic synapse
    108285792 (AKT2)
   04722 Neurotrophin signaling pathway
    108285792 (AKT2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    108285792 (AKT2)
  09149 Aging
   04211 Longevity regulating pathway
    108285792 (AKT2)
   04213 Longevity regulating pathway - multiple species
    108285792 (AKT2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108285792 (AKT2)
   05205 Proteoglycans in cancer
    108285792 (AKT2)
   05207 Chemical carcinogenesis - receptor activation
    108285792 (AKT2)
   05208 Chemical carcinogenesis - reactive oxygen species
    108285792 (AKT2)
   05230 Central carbon metabolism in cancer
    108285792 (AKT2)
   05231 Choline metabolism in cancer
    108285792 (AKT2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108285792 (AKT2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    108285792 (AKT2)
   05212 Pancreatic cancer
    108285792 (AKT2)
   05225 Hepatocellular carcinoma
    108285792 (AKT2)
   05226 Gastric cancer
    108285792 (AKT2)
   05214 Glioma
    108285792 (AKT2)
   05221 Acute myeloid leukemia
    108285792 (AKT2)
   05220 Chronic myeloid leukemia
    108285792 (AKT2)
   05218 Melanoma
    108285792 (AKT2)
   05211 Renal cell carcinoma
    108285792 (AKT2)
   05215 Prostate cancer
    108285792 (AKT2)
   05213 Endometrial cancer
    108285792 (AKT2)
   05224 Breast cancer
    108285792 (AKT2)
   05222 Small cell lung cancer
    108285792 (AKT2)
   05223 Non-small cell lung cancer
    108285792 (AKT2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108285792 (AKT2)
   05170 Human immunodeficiency virus 1 infection
    108285792 (AKT2)
   05161 Hepatitis B
    108285792 (AKT2)
   05160 Hepatitis C
    108285792 (AKT2)
   05164 Influenza A
    108285792 (AKT2)
   05162 Measles
    108285792 (AKT2)
   05168 Herpes simplex virus 1 infection
    108285792 (AKT2)
   05163 Human cytomegalovirus infection
    108285792 (AKT2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108285792 (AKT2)
   05169 Epstein-Barr virus infection
    108285792 (AKT2)
   05165 Human papillomavirus infection
    108285792 (AKT2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108285792 (AKT2)
   05135 Yersinia infection
    108285792 (AKT2)
   05152 Tuberculosis
    108285792 (AKT2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108285792 (AKT2)
   05142 Chagas disease
    108285792 (AKT2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108285792 (AKT2)
   05017 Spinocerebellar ataxia
    108285792 (AKT2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108285792 (AKT2)
   05418 Fluid shear stress and atherosclerosis
    108285792 (AKT2)
   05415 Diabetic cardiomyopathy
    108285792 (AKT2)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108285792 (AKT2)
   04932 Non-alcoholic fatty liver disease
    108285792 (AKT2)
   04931 Insulin resistance
    108285792 (AKT2)
   04933 AGE-RAGE signaling pathway in diabetic complications
    108285792 (AKT2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108285792 (AKT2)
   01524 Platinum drug resistance
    108285792 (AKT2)
   01522 Endocrine resistance
    108285792 (AKT2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cimi01001]
    108285792 (AKT2)
Enzymes [BR:cimi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     108285792 (AKT2)
Protein kinases [BR:cimi01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   108285792 (AKT2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 Seadorna_VP7
Other DBs
NCBI-GeneID: 108285792
NCBI-ProteinID: XP_017358715
Ensembl: ENSCCAG00000027781
UniProt: A0A2K5QVH7
LinkDB
Position
Unknown
AA seq 481 aa
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRALGEDPM
DYKCGSPSDSSVAEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAQEVMEHRFFLSINWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIR
E
NT seq 1446 nt   +upstreamnt  +downstreamnt
atgaacgaggtgtctgtcatcaaagaaggctggctccacaagcgcggtgaatacatcaag
acctggaggccacggtacttcctgctgaagagtgacggctccttcattgggtacaaggag
aggcccgaggccccagatcagaccctgccccccttaaacaacttctctgtagcagaatgc
cagctgatgaagaccgagaggccgaggcccaacaccttcgtcatacgctgcctgcagtgg
accacagtcattgagaggaccttccacgtggattctccagatgagagggaggagtggatg
cgggccatccagatggtcgccaacagcctcaagcagcgggccctgggcgaggaccccatg
gactacaagtgtggctcccccagtgactcctctgtggccgaggagatggaagtggcggtc
agcaaggcacgggccaaagtgaccatgaatgacttcgactatctcaaactccttggcaag
ggaacctttggcaaagtcatcctggtgcgggagaaggccactggccgctactacgccatg
aagatcctgcggaaggaagtcatcattgccaaggatgaagtcgctcacacggtcaccgag
agccgggtcctccagaacaccaggcacccgttcctcactgcactgaagtacgccttccag
acccacgaccgcctgtgcttcgtgatggagtacgccaacggtggcgagctgttcttccac
ctgtcccgggagcgtgtcttcacagaggagcgggcccggttttacggtgcggagatagtc
tcggctcttgagtacttgcactctcgggacgtggtgtaccgcgacatcaagctggaaaac
ctcatgctggacaaagatggccacatcaagatcactgactttggtctctgcaaagaaggc
atcagtgacggggccaccatgaaaaccttctgtgggactccggagtacctggcgcctgag
gtgctggaggacaacgactatggccgggcagtggactggtgggggctgggcgtggtcatg
tacgagatgatgtgtggccgcctgcccttctacaaccaggaccacgagcgcctgttcgag
ctcatcctcatggaggagattcgcttcccgcgcacgctcagccccgaggccaagtccctg
cttgctggactgcttaagaaggaccccaagcagaggcttggtggggggcccagtgatgcc
caggaggtcatggagcacaggttcttcctcagcatcaactggcaggatgtggtccagaag
aagctcctgccacccttcaaacctcaggtcacgtctgaggtcgacacacggtacttcgat
gatgaattcaccgcccagtccatcacaatcacaccccccgaccgctatgacagcctgggc
tccctggagctggaccagcggacccacttcccccagttctcctactcggccagcatccgg
gagtga

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