Cebus imitator (Panamanian white-faced capuchin): 108288448
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Entry
108288448 CDS
T08783
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
cimi
Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi00310
Lysine degradation
cimi01100
Metabolic pathways
cimi05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
cimi00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
108288448 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
108288448 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
cimi03036
]
108288448 (DOT1L)
Enzymes [BR:
cimi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
108288448 (DOT1L)
Chromosome and associated proteins [BR:
cimi03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
108288448 (DOT1L)
HMT complexes
Dot1-containing complex
108288448 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
108288448
NCBI-ProteinID:
XP_037586954
Ensembl:
ENSCCAG00000021296
LinkDB
All DBs
Position
Unknown
AA seq
1857 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGKAPSSSVRVVVTWLRKGGLGVPAGCPAEGSSGLGSLV
PQEPGGPSSFFFFLFLEGSLGCLSSVTSSVVPVPAALECIFWLYLASFLRTLSRGGLCGL
LWSDSVWEEREDVCSSGFCPLARPWWVRRAWRGCGWARASPWSVAPADIGTIMRVVELSP
LKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQREGKSNAATPTK
GPEGKAAGPAEAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMN
TANPERKPKKNQTALDLLHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVA
PTPPALQKLLESFRIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGTAQQLLSHCQA
QKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRTLRSQSLQ
LLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQ
LKSCVPPDDTLALHLRGKGTLGRELEPDAGRLHLELDCAKFSLPHLSSMSPELSMNGHTP
SYELCSALSRPSPKQNTPQYLASPLDQEVVPCTPSHGGRPRVEKLSGLAVPEYTGLSPAK
IVLRRHLSQDHTVPGRPAASELHPRAEHTKENGLPYQSPSVPSSMKLSPQDPRPPSPGTL
QLAGEKSSEKGLRERAYSSGGEPITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERVR
STPSPVLQPRDPSSTLEKHIGANAHSAGSKSLALAPAGFSYAGSVAISGTLAGSPASLAP
GAEPAALDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSRPASPAHQLSSSPLLSGAAHG
PLPEASKGDLPSDSGFSDPESEAKRRIVFTIATGAGGTKQSPSSKHSPLTASARGDCVPS
HGQDSRKRGRRKRASTGTPSLTAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVNNINQPL
EITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSHTNGAHYSPLTSDEEPGSEDEPSSA
RIERKIATISLESKSPPKTLENGGGVAGRRPTPAGRPVNSSKWKSTFSPISDIGLAKAAD
SPLQAGPTLSQSSLFAFRPALEETPADAKLAAHPRKGFPGSLSGADGLSPSTNPANCCTF
GGGLAAELSSHGFSDGASVPHKGPEAAGLSSPLGFPSQRTKEASDANPFLSKRQLDGLAG
LKGEGGRGKEVGEGGLPLCGPADKSALPAGKAAKARDRELDLKNGHNLFISAAAVPPGGL
LSGPVLAPAASSAGGSGSSTQTHRPFLGPFPPGPQFALGPMALQANLSSVAGSSVLQSLF
SSVPAAAGLVHVSSAATRLTNSHTIGSFSGVAGSTVGGVFNHAVPSASAHPFGARVGRGA
ACGSATLGPSPLQAAASASASSFQAPASVETRPPPPPPPPPLPPPAHLGRPPAGPPILHA
LPPNAALPPPPTLLASNPEPVLLQSLASLPPNQAFLPPASAASLPPANASLSIKLTSLPH
KGARPSFTVHHQPLPRLALAQAAPGIPQASATGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5574 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctaccggtctacgacaaacatcatgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaagaaatcccagatctcaagctcgctatggagaattacgtttta
attgactatgacaccaaaagctttgagagcatgcagaggctctgtgacaagtacaaccgt
gccatcgacagcatccaccagctgtggaagggcaccacgcaacccatgaagctgaacacg
cggccgtccaccgggcttctgcgccacatcctgcagcaggtctacaaccactcggtgacc
gaccctgagaagctcaacaactacgagcccttctcccccgaggtgtacggggagacctcc
ttcgacctggtggcccagatgatcgacgagatcaagatgaccgacgatgacctgtttgtg
gacctagggagcggtgtgggccaggttgtgctccaggtcgccgccgccaccaactgcaaa
catcactatggcgtcgagaaagcagacatcccggccaagtatgcggagaccatggaccgc
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacattggagaga
ggcgatttcctctcggaagagtggagggagcgaattgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtaaggcgccctcctcgtcggtccgtgttgttgtgacatggttgaggaagggt
ggcctgggggtccctgcagggtgtcctgcagaaggcagctcaggcttggggtccttagtc
ccccaggagccaggtggtccttcttcattctttttttttctttttttagaaggcagcctt
ggctgcctcagttctgttacctcctccgtggtccccgtccccgctgccctagaatgcatc
ttctggctgtatctcgccagctttctccgcacgctcagccgcggcggcctctgtgggcta
ctgtggtctgactcagtgtgggaggagagggaggacgtgtgcagctcagggttctgtccc
ctggctcgcccttggtgggtgaggcgggcgtggaggggctgcgggtgggctcgggcctca
ccttggtctgtggctcccgcagacatcggcaccatcatgcgtgtggtggagctatcgccc
ctcaagggctcggtgtcatggacggggaagccggtgtcgtactacctgcacactattgac
cgcaccatacttgaaaattatttttctagtctgaaaaacccaaaactcagggaggaacag
gaggcagcccggcgccgccagcagcgcgagggcaagagcaacgcggccacgcccaccaag
ggtcccgagggcaaggcagctggccctgccgaagcccccatggactctggtgctgaggaa
gagaaggcgggagcagccaccgtgaagaagccgtctccctccaaagcccgcaagaagaag
ctgaacaagaaggggaggaagatggcaggccgcaagcgtgggcgccccaagaagatgaac
actgcgaaccccgagcggaagcccaagaagaaccaaactgcactggatctcctacacgcg
cagaccgtgtctcagacggcggcctcctcgccccaggatgcctacaggtcccctcacagc
ccgttctaccagctacctccaagcgtgcagcggcactcccccaacccgctgctggtggcg
cccaccccacccgcactacagaagctgctagagtccttcaggatccagtacctgcagttc
ctggcgtacacgaagaccccccagtacaaggccagcctgcaggagctgctgggccaggag
aaggagaagaacgcccagctcctgggcacggctcagcagctcctcagccactgccaggcc
cagaaggaggagatcaggaggctgttccagcagaagctggatgagctgggtgtgaaggcg
ctgacctacaacgacctgattcaagcgcagaaggagatctccgcccataaccagcagctg
cgggagcagtcggagcagctggagcaggacaaccgcacgctccgcagtcagagcctgcag
ctgctcaaggctcgctgtgaggagctacagctggactgggccacgctgtccctggagaag
ctgctgaaggagaagcaggccctgaagagccagatctcagagaagcagaggcactgcctg
gagctgcagatcagcatcgtggagctggagaagagccagcggcagcaggagctcctgcag
ctcaagtcctgtgtgccaccagacgacaccctggccctgcacctgcgcgggaagggcacc
ctgggccgcgagctggagcctgacgccggtcggctgcatctggagctggactgcgccaag
ttctcgctgcctcacttgagcagcatgagcccagagctctccatgaatggccatactccc
agctatgagctctgcagcgcgctgagccggccctcgcccaagcagaacacgccccagtac
ctggcctcacccctagaccaggaggtggtaccctgcacccccagccacggcggccgtccg
cgcgtggagaagctgtctggcctggctgtgcccgagtacaccgggctgtccccggccaag
attgtgctgaggcggcacctcagccaggaccacacggtgccaggcaggccggccgccagc
gagctgcacccgagagctgagcacaccaaggagaatggccttccctaccagagccccagc
gtgcccagcagcatgaagctgagcccccaggacccacggcccccatcccctgggaccctg
cagcttgctggagagaagagcagtgagaagggcctgagagagcgtgcctacagcagcggc
ggggagcccatcaccagcctgcccatcagcatcccactcagcaccgtgcagccgaacaag
ctcccggtcagcatccccctggccagcgtggtgctgcccagccgcgctgagagggtgaga
agcacccccagtcctgtgctgcagccccgagacccctcgtccacacttgaaaagcatatt
ggtgctaatgcccacagtgctgggagcaaaagccttgccctggcccctgcaggcttctcc
tatgctggctcggtggctatcagcgggaccctggcaggcagcccagcctctctcgcccct
ggagctgagcccgccgccttggatgagtcctccagctctgggagtctgtttgccactgtg
gggtcccgcagctccacgccacagcatcccctgctgctggcacagccccggaactcgcgc
ccggcctctcccgcccaccagctctcctccagccccctgctcagtggggctgcccacggc
ccgctccccgaggccagcaagggggacctgccctccgattccggcttctcagatccggag
agcgaggccaagaggaggatcgtgttcaccatcgccaccggcgcgggcggcaccaagcag
tcgccttccagcaaacacagccccctgaccgccagcgcccgcggggactgtgtgccgagc
cacggccaggacagccgcaagcgtggccggcggaagcgagcgtcaacggggacacccagc
ttgaccgcaggcgtgtcccccaagcgccgagccctgccgtctgtcgctggtcttttcacg
cagccttcagggtctcctctaaacctcaactccatggtcaataacatcaaccagcccctg
gagattacggccatctcatcccctgagacctccctgaagagctcccctgtgccctaccag
gaccacgatcagccccccgtgctcaagaaagagcggcccctgagccacaccaatggggcg
cattactccccgctcacctccgacgaggagccaggctctgaggacgagcccagcagcgcc
cgaattgagagaaaaattgcaacaatctccttagaaagcaaatctccccccaaaaccttg
gaaaatggtggtggcgtggcgggaaggaggcccacgccggcaggcaggccagtcaatagc
agcaagtggaagtccaccttctcgccgatctccgacatcggcctggccaaggctgcggac
agccccctgcaggccggccccaccctgagccagagctccctgttcgcgttccggcctgcc
ctggaggagacccccgccgatgccaagctggctgcccaccccaggaaaggctttcccggc
tccctgtcaggggccgacggactcagccccagcaccaaccctgcgaactgctgcaccttc
ggcgggggcctggccgctgagctgagttcacacggcttcagtgatggtgcttctgtcccc
cacaagggccccgaggcggccggcctgagctccccgctgggcttcccctcgcagcgcacc
aaggaggcctcggacgccaaccctttcctgagcaagaggcagctagacggcctggccggg
ctgaagggcgagggtggccgcggcaaggaggtgggggagggaggcctgccgctgtgcggc
cccgcggacaaaagtgcgctgcccgccggcaaggccgccaaggcccgggaccgtgagctc
gacctcaagaacggccacaacctcttcatctccgcggccgcggtgcctcccggaggcctc
ctcagcggcccggtcctggccccggcggcgtcctctgcaggcggctctgggtcctccacc
cagacacaccggcccttcctgggccccttcccgccagggccgcagttcgcgctgggcccc
atggccctgcaggccaatctgagctccgtggccggctcctccgtgctgcagtcgctcttc
agctctgtgccggccgccgctggcctggtgcacgtgtcgtccgctgccaccagactcacc
aactcgcacaccattggcagcttttccggggtggcaggcagcacagttggaggtgtcttt
aaccacgcggtgccttccgcctctgctcatccgtttggagcccgtgtcggccgcggggct
gcgtgtggcagtgccacgctgggcccgagcccgctgcaggcggcggccagcgcctcggcc
tcttcctttcaggccccggcctcggttgagacccggccgccccctccgcctccgcctccc
ccgctgcccccgcctgcgcacctgggccggccccccgcggggcctcccatcctccacgct
ctcccacctaacgccgccttgcctcctcccccaacgctgctggcctctaaccctgagccc
gtgcttctgcagagcctcgcgtccctcccgcctaaccaagctttcttgccccccgcctct
gctgcctctctgccgcctgctaatgcctctttgtctatcaagctcacctccctcccgcac
aagggcgcccgcccctccttcacggtgcaccaccagcccctgccccggctggccctggca
caggccgcgcccgggatcccgcaggccagcgccacggggccgtccgctgtgtgggtgtcc
cttggcatgccgcctccttatgccgcgcacctttcaggggttaagccgcgataa
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integrated database retrieval system
