Cebus imitator (Panamanian white-faced capuchin): 108306253
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Entry
108306253 CDS
T08783
Symbol
CYP17A1
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase isoform X1
KO
K00512
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:
1.14.14.19
1.14.14.32
]
Organism
cimi
Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi00140
Steroid hormone biosynthesis
cimi01100
Metabolic pathways
cimi04913
Ovarian steroidogenesis
cimi04917
Prolactin signaling pathway
cimi04927
Cortisol synthesis and secretion
cimi04934
Cushing syndrome
Module
cimi_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
cimi_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
cimi_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
cimi00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
108306253 (CYP17A1)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
108306253 (CYP17A1)
04917 Prolactin signaling pathway
108306253 (CYP17A1)
04927 Cortisol synthesis and secretion
108306253 (CYP17A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
108306253 (CYP17A1)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
cimi00199
]
108306253 (CYP17A1)
Enzymes [BR:
cimi01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.19 steroid 17alpha-monooxygenase
108306253 (CYP17A1)
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
108306253 (CYP17A1)
Cytochrome P450 [BR:
cimi00199
]
Cytochrome P450, animal type
CYP17 family
108306253 (CYP17A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
108306253
NCBI-ProteinID:
XP_017386578
Ensembl:
ENSCCAG00000022170
VGNC:
82845
UniProt:
A0A2K5PYY2
LinkDB
All DBs
Position
Unknown
AA seq
507 aa
AA seq
DB search
MWELVTLLLFTLTYFFWPKRRSPGAKYPKSLLSLPVVGSLPFLPRHGHMHQNLFKLQKKY
GPIFSLRMGSNLTVIVGNHQLAKEVLMKKGKDFAGRPQVATIDILSNKGKGIAFADYSAQ
WQLHRRLAMATFSLFKEGDQKLEKIICQEISILCDMLATHDGQSIDMSFPVFMAVTNVIS
LICFNSSYKSGAPELKIVETYNHGIVEALAKESLVDMFPWLKIFPSKTLEKLKANVKIRN
DLLNKIIGNYKEKFRSDSIISMLDVLMQAKMNADNGNTSPDQDAELLSENHILTTIGDIF
GAGVETTTSVVKWIVAYLLHNPQVKKKLYEEIDQNVGFNRTPTISDRSCLLLLEATIREV
LRIRPVAPMLIPHKANVDSSIGEFAVDKGTHVVINLWALHHNEEWHQPDKFMPERFLNQA
GTQLISPTLSYLPFGAGPRSCIGEILARQELFLIMSWMLQRFDLEVPDDGQLPSLEGNPK
VVFMIDSFKVKIKVRQAWREAQAEGTT
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
atgtgggagcttgtgactctcttgctgttcaccctcacctatttcttttggcccaagaga
aggtcccctggtgccaagtaccccaagagcctcctgtccctgcccgtggtgggcagcctg
ccattcctccccagacatggccatatgcatcagaacttattcaagttgcagaaaaaatat
ggacctatcttttcccttcgtatgggcagcaaccttacggtgattgtcggcaaccatcag
ctggccaaggaggtacttatgaagaagggcaaggactttgctggtcggcctcaagtggca
accatagacatcctgtccaacaagggcaagggcattgccttcgctgactacagtgcacaa
tggcagctgcatcgaaggcttgcgatggccaccttttccctgttcaaggaaggcgatcag
aagctggagaagatcatttgtcaggaaatcagtatattgtgtgatatgctggccacccac
gatggacagagcatagacatgtcctttcctgtcttcatggcggtaaccaatgtaatctcc
ttgatctgcttcaattcctcctacaagagtggagcccctgagttgaagatcgtagagact
tacaaccatggcattgtagaagccctggccaaggagagcctggtagacatgttcccctgg
ttgaagattttccccagcaaaaccctggaaaaattaaaggccaatgttaaaatacgaaat
gatctgctaaataaaataattggaaattacaaggagaaattccgcagcgactctatcatc
agcatgctggatgtcctgatgcaagcgaagatgaatgcggataatggcaacaccagccca
gatcaagacgcagagctgctttcagaaaaccacattctcaccaccataggggacatcttt
ggggccggcgtggagaccaccacctctgtggtcaagtggatcgtggcctacctgctgcac
aatcctcaggtgaagaagaagctctacgaggagattgaccagaatgtgggtttcaaccgc
acaccaacgatcagtgaccgtagctgtctgctcctgctggaggccaccatccgagaggtg
cttcgcatcaggcccgtggcccctatgctcatcccccacaaggccaacgttgactccagc
attggtgagtttgctgtggacaagggtacccatgttgttatcaatctgtgggcgctgcat
cacaacgaagagtggcaccagccggacaagttcatgcctgagcgtttcttgaatcaagcg
ggaacccagctcatctcaccgacattaagctacttgcccttcggagcaggacctcgctcc
tgtataggtgagatcctggcccgccaggagctcttcctcatcatgtcctggatgctgcag
aggttcgacctggaggtgccagatgatgggcagctgccctccctggaaggcaaccccaag
gtggtctttatgatcgactctttcaaagtgaagatcaaggtgcgccaggcctggagggaa
gcccaggctgagggtaccacctaa
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