KEGG   Cebus imitator (Panamanian white-faced capuchin): 108310295
Entry
108310295         CDS       T08783                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cimi  Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi00562  Inositol phosphate metabolism
cimi01100  Metabolic pathways
cimi04015  Rap1 signaling pathway
cimi04020  Calcium signaling pathway
cimi04022  cGMP-PKG signaling pathway
cimi04062  Chemokine signaling pathway
cimi04070  Phosphatidylinositol signaling system
cimi04071  Sphingolipid signaling pathway
cimi04072  Phospholipase D signaling pathway
cimi04081  Hormone signaling
cimi04082  Neuroactive ligand signaling
cimi04261  Adrenergic signaling in cardiomyocytes
cimi04270  Vascular smooth muscle contraction
cimi04310  Wnt signaling pathway
cimi04371  Apelin signaling pathway
cimi04540  Gap junction
cimi04611  Platelet activation
cimi04613  Neutrophil extracellular trap formation
cimi04621  NOD-like receptor signaling pathway
cimi04713  Circadian entrainment
cimi04720  Long-term potentiation
cimi04723  Retrograde endocannabinoid signaling
cimi04724  Glutamatergic synapse
cimi04725  Cholinergic synapse
cimi04726  Serotonergic synapse
cimi04728  Dopaminergic synapse
cimi04730  Long-term depression
cimi04742  Taste transduction
cimi04750  Inflammatory mediator regulation of TRP channels
cimi04911  Insulin secretion
cimi04912  GnRH signaling pathway
cimi04915  Estrogen signaling pathway
cimi04916  Melanogenesis
cimi04918  Thyroid hormone synthesis
cimi04919  Thyroid hormone signaling pathway
cimi04921  Oxytocin signaling pathway
cimi04922  Glucagon signaling pathway
cimi04924  Renin secretion
cimi04925  Aldosterone synthesis and secretion
cimi04926  Relaxin signaling pathway
cimi04927  Cortisol synthesis and secretion
cimi04928  Parathyroid hormone synthesis, secretion and action
cimi04929  GnRH secretion
cimi04933  AGE-RAGE signaling pathway in diabetic complications
cimi04934  Cushing syndrome
cimi04935  Growth hormone synthesis, secretion and action
cimi04961  Endocrine and other factor-regulated calcium reabsorption
cimi04970  Salivary secretion
cimi04971  Gastric acid secretion
cimi04972  Pancreatic secretion
cimi04973  Carbohydrate digestion and absorption
cimi05010  Alzheimer disease
cimi05016  Huntington disease
cimi05017  Spinocerebellar ataxia
cimi05022  Pathways of neurodegeneration - multiple diseases
cimi05142  Chagas disease
cimi05143  African trypanosomiasis
cimi05146  Amoebiasis
cimi05163  Human cytomegalovirus infection
cimi05200  Pathways in cancer
cimi05415  Diabetic cardiomyopathy
cimi05417  Lipid and atherosclerosis
Module
cimi_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cimi00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    108310295 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    108310295 (PLCB3)
   04310 Wnt signaling pathway
    108310295 (PLCB3)
   04371 Apelin signaling pathway
    108310295 (PLCB3)
   04020 Calcium signaling pathway
    108310295 (PLCB3)
   04070 Phosphatidylinositol signaling system
    108310295 (PLCB3)
   04072 Phospholipase D signaling pathway
    108310295 (PLCB3)
   04071 Sphingolipid signaling pathway
    108310295 (PLCB3)
   04022 cGMP-PKG signaling pathway
    108310295 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    108310295 (PLCB3)
   04081 Hormone signaling
    108310295 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    108310295 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    108310295 (PLCB3)
   04613 Neutrophil extracellular trap formation
    108310295 (PLCB3)
   04621 NOD-like receptor signaling pathway
    108310295 (PLCB3)
   04062 Chemokine signaling pathway
    108310295 (PLCB3)
  09152 Endocrine system
   04911 Insulin secretion
    108310295 (PLCB3)
   04922 Glucagon signaling pathway
    108310295 (PLCB3)
   04929 GnRH secretion
    108310295 (PLCB3)
   04912 GnRH signaling pathway
    108310295 (PLCB3)
   04915 Estrogen signaling pathway
    108310295 (PLCB3)
   04921 Oxytocin signaling pathway
    108310295 (PLCB3)
   04926 Relaxin signaling pathway
    108310295 (PLCB3)
   04935 Growth hormone synthesis, secretion and action
    108310295 (PLCB3)
   04918 Thyroid hormone synthesis
    108310295 (PLCB3)
   04919 Thyroid hormone signaling pathway
    108310295 (PLCB3)
   04928 Parathyroid hormone synthesis, secretion and action
    108310295 (PLCB3)
   04916 Melanogenesis
    108310295 (PLCB3)
   04924 Renin secretion
    108310295 (PLCB3)
   04925 Aldosterone synthesis and secretion
    108310295 (PLCB3)
   04927 Cortisol synthesis and secretion
    108310295 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108310295 (PLCB3)
   04270 Vascular smooth muscle contraction
    108310295 (PLCB3)
  09154 Digestive system
   04970 Salivary secretion
    108310295 (PLCB3)
   04971 Gastric acid secretion
    108310295 (PLCB3)
   04972 Pancreatic secretion
    108310295 (PLCB3)
   04973 Carbohydrate digestion and absorption
    108310295 (PLCB3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    108310295 (PLCB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    108310295 (PLCB3)
   04725 Cholinergic synapse
    108310295 (PLCB3)
   04728 Dopaminergic synapse
    108310295 (PLCB3)
   04726 Serotonergic synapse
    108310295 (PLCB3)
   04720 Long-term potentiation
    108310295 (PLCB3)
   04730 Long-term depression
    108310295 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    108310295 (PLCB3)
  09157 Sensory system
   04742 Taste transduction
    108310295 (PLCB3)
   04750 Inflammatory mediator regulation of TRP channels
    108310295 (PLCB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    108310295 (PLCB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108310295 (PLCB3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    108310295 (PLCB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    108310295 (PLCB3)
   05142 Chagas disease
    108310295 (PLCB3)
   05143 African trypanosomiasis
    108310295 (PLCB3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108310295 (PLCB3)
   05016 Huntington disease
    108310295 (PLCB3)
   05017 Spinocerebellar ataxia
    108310295 (PLCB3)
   05022 Pathways of neurodegeneration - multiple diseases
    108310295 (PLCB3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108310295 (PLCB3)
   05415 Diabetic cardiomyopathy
    108310295 (PLCB3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    108310295 (PLCB3)
   04934 Cushing syndrome
    108310295 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cimi04131]
    108310295 (PLCB3)
Enzymes [BR:cimi01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     108310295 (PLCB3)
Membrane trafficking [BR:cimi04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    108310295 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    108310295 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 108310295
NCBI-ProteinID: XP_017392740
Ensembl: ENSCCAG00000015511
UniProt: A0A2K5PGV0
LinkDB
Position
Unknown
AA seq 1233 aa
MAGAQPGVHALQLEPPTVVETLRRGSKFIKWDEETSSRNLVTLRVDPNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVSGPDPVNTVFLNF
MAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNKQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHQPRTGGPDG
AGRKRPLEQSNSALSESSATTEPSSPQLGSPSSDSCPGLSNGEEGALEKPSLELRKSLGE
EGLNRGPYALGPADREDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEPV
KFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYM
PQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV
DGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEP
FAFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLI
YTEASDYIPDDHQDYAEALINPIKHVSLMDQRARQLAALIGESEAQAGHETCQDTQSQQL
GSQLSPNPSSSPLDASPRRPPGPATSPTSASLSSPGQRDDLIASILSEVAPTPLDELRGH
KALVKLRSRQERELRELRKKHQRKVVTLTRRLLDGLAQAQAESRCRPRPGALGGAADEDS
KEGEDEAKRYQEFQNRQVQSLLELREAQADAEAQRRLEHLKQAQQRLREVVLDANTTQFK
RLKETNEREKKELQKILDRKRHNSISEAKTRDKHKKEVELTEINRRHITESVNSIRRLEE
AQKQRHDRLVAGQQQVLQQLAEEEPMLLAQLAQECQEQRARLPQEIRRSLLGETPEGLGD
RPLVACASNGHAPGSSGHLSGADSESQEENTQL
NT seq 3702 nt   +upstreamnt  +downstreamnt
atggcgggcgcccagcccggcgtccacgcgctgcagctggagccgcccaccgtggtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggagacctccagtcggaacctg
gtcaccctgcgtgtggaccccaatggcttcttcttgtactggacgggccccaacatggag
gtggatacactggacatcagctccatcagggacacacggacgggccgatacgcccgcctg
cccaaggatcccaagatccgggaagttctgggctttgggggtcccgatgcccggctggag
gagaagctgatgacggtggtatctgggccagatcccgtgaacacagtgttcttgaacttc
atggccgtgcaggacgacacagccaaggtctggtccgaggagctgtttaagctggctatg
aacatcctggcacagaatgcctcccggaacaccttcctgcgcaaagcatacacgaagctg
aagctgcaggtgaaccaggatggtcggatccccgtcaagaacatccttaagatgttctca
gccgacaagaagcgagtggagactgcgctggaatcctgtggcctcaacttcaaccggagc
gagtccatccgacccgatgagttttccttggaaatctttgaacggttcctgaacaagctg
tgtttgcggccggacattgacaagatcctgctggagataggtgccaagggcaagccatac
ctgacgctggagcagctcatggacttcatcaaccagaagcaacgtgacccaagactcaac
gaagtgctgtacccacccctgcggccctcccaagcccggctgctcattgagaagtatgag
cccaacaagcagtttctggagcgagaccagatgtccatggaaggctttagccgctacctg
ggaggcgaggagaacggcatcctgcccctggaagccctggatctgagcgcggacatgacc
cagccgctgagtgcctacttcatcaactcctcacataacacctatctcactgcggggcag
ctggctgggacctcgtcagtggagatgtaccgccaggccctgctctggggctgccgctgt
gtggagctggacgtgtggaaggggcggccgcccgaggaggagcccttcatcacccatggc
ttcaccatgaccacggaggtgcctctgcgagacgtgctggaggccattgccgagaccgcc
ttcaagacctcgccctaccccgtcatcctctccttcgagaaccacgtggactcggcaaag
cagcaggcaaagatggccgagtactgccgctccatctttggagatgcattgcttatcgac
cctctggacaagtacccgctggccccaggcgtccccctgcccagcccccaggacctgatg
ggacgaatcctggtgaagaacaagaagcggcaccagcctaggacgggtggcccagacggc
gccgggcgcaagcggccgctggaacagagcaactcggccctgagcgagagctccgccacc
accgagccctcctccccgcagcttgggtctcccagctctgacagctgcccaggcctaagc
aatggggaggagggggcgctcgagaagcccagcctggagcttcgaaaatctttgggcgag
gagggcctgaaccggggcccctatgctcttggacctgctgaccgtgaggatgaggaggaa
gacgaggaagaagaggaacagacagaccccaaaaagccgaccacagatgagggcacagcc
agcagcgaggtcaatgccaccgaggagatgtccacgcttgtcaactacatcgagcctgtc
aagttcaagtcctttgaggctgctcgaaagaggaacaaatgcttcgagatgtcgtccttc
gtggagaccaaggccatggagcagctgaccaagagccccatggagtttgtggaatacaac
aagcagcagctcagccgcatctaccccaagggcacccgcgtggactcctccaactacatg
ccccagctcttctggaacgtagggtgccagctcgttgcactcaacttccagaccctggat
gtggcgatgcagctcaacgcgggcgtgttcgagtacaatgggcgcagcgggtacctgctc
aagccggagttcatgcggcggccggacaaatccttcgaccccttcaccgaggtcatcgtg
gatggcatcgtggccaacgccttgcgggtcaaggtgatctcggggcagttcctatccgac
aggaaggtgggcatctacgtggaggtggacatgttcggcctccctgttgacacgcggcgc
aagtaccgcacccggacctctcaggggaactccttcaaccccgtgtgggacgaggagccg
tttgccttccccaaggtggtgctgcccacgctggcttcgcttcgcatcgcagcctttgag
gagggcggcaaattcgtggggcaccggatcctgcctgtctctgccatccgctctgggtac
cactatgtctgcctgcggaacgaggccaaccaaccgctgtgcctgccggccctgctcatc
tacaccgaggcctcggactacattcctgacgaccaccaggactacgcggaggccttgatc
aaccccattaagcacgtcagcctgatggaccagagggcccgccaactggctgccctcatt
ggtgagagtgaggctcaggctggccatgagacatgccaggacacccagtctcagcagctg
gggtctcagctgtccccaaaccccagctctagcccactggatgcctccccacgccggccc
cccggccctgccacctcccctaccagcgcctctctgagcagcccagggcagcgcgacgat
ctcattgccagcattctctcagaggtggcccccaccccgctggacgagctccgaggacac
aaggctctggtcaagctccggagccggcaggagcgagagcttcgggagctgcgcaagaag
catcagcggaaggtggtcaccctcacccgccgcctgctggacggcctggctcaggcacag
gcagagagcaggtgccggccgcggcctggtgccctaggtggggccgctgacgaggactca
aaggagggggaggacgaggcgaagcgctatcaggagttccagaacagacaggtgcagagc
ctgctggagctgcgggaggcccaggcggacgcagaggcccagcggaggctggagcacctg
aaacaggctcagcagcggctcagggaggtcgtccttgatgcaaacacaactcagttcaag
aggctgaaggagacgaacgagagggagaagaaggagctacagaagatcctggacagaaag
cgccacaacagcatctcggaggccaagacgagagacaagcataagaaggaggtggaactg
acagagattaatcgtcggcacatcactgagtctgtcaactccatccgtcggctggaggag
gcccagaagcagcggcacgaccgtcttgtggcggggcagcagcaggtcctgcaacagctg
gcagaagaggagcccatgctgctggctcagctggcccaggagtgtcaggagcagcgggcg
aggctgccccaggagatccgccggagcctgctgggcgagacgccagaggggctgggggac
aggcctctggtggcctgtgccagcaacggtcacgcacccgggagcagcgggcacctgtcg
ggtgctgactcggagagccaggaggagaacacgcagctctga

DBGET integrated database retrieval system