Cebus imitator (Panamanian white-faced capuchin): 108313460
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Entry
108313460 CDS
T08783
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
cimi
Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi00562
Inositol phosphate metabolism
cimi01100
Metabolic pathways
cimi01521
EGFR tyrosine kinase inhibitor resistance
cimi04012
ErbB signaling pathway
cimi04014
Ras signaling pathway
cimi04020
Calcium signaling pathway
cimi04062
Chemokine signaling pathway
cimi04064
NF-kappa B signaling pathway
cimi04066
HIF-1 signaling pathway
cimi04070
Phosphatidylinositol signaling system
cimi04072
Phospholipase D signaling pathway
cimi04360
Axon guidance
cimi04370
VEGF signaling pathway
cimi04380
Osteoclast differentiation
cimi04611
Platelet activation
cimi04613
Neutrophil extracellular trap formation
cimi04625
C-type lectin receptor signaling pathway
cimi04650
Natural killer cell mediated cytotoxicity
cimi04662
B cell receptor signaling pathway
cimi04664
Fc epsilon RI signaling pathway
cimi04666
Fc gamma R-mediated phagocytosis
cimi04670
Leukocyte transendothelial migration
cimi04722
Neurotrophin signaling pathway
cimi04750
Inflammatory mediator regulation of TRP channels
cimi04919
Thyroid hormone signaling pathway
cimi04933
AGE-RAGE signaling pathway in diabetic complications
cimi04935
Growth hormone synthesis, secretion and action
cimi05167
Kaposi sarcoma-associated herpesvirus infection
cimi05169
Epstein-Barr virus infection
cimi05170
Human immunodeficiency virus 1 infection
cimi05171
Coronavirus disease - COVID-19
cimi05200
Pathways in cancer
cimi05205
Proteoglycans in cancer
cimi05206
MicroRNAs in cancer
cimi05214
Glioma
cimi05223
Non-small cell lung cancer
cimi05225
Hepatocellular carcinoma
Module
cimi_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
cimi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
108313460 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
108313460 (PLCG2)
04014 Ras signaling pathway
108313460 (PLCG2)
04370 VEGF signaling pathway
108313460 (PLCG2)
04064 NF-kappa B signaling pathway
108313460 (PLCG2)
04066 HIF-1 signaling pathway
108313460 (PLCG2)
04020 Calcium signaling pathway
108313460 (PLCG2)
04070 Phosphatidylinositol signaling system
108313460 (PLCG2)
04072 Phospholipase D signaling pathway
108313460 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
108313460 (PLCG2)
04613 Neutrophil extracellular trap formation
108313460 (PLCG2)
04625 C-type lectin receptor signaling pathway
108313460 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
108313460 (PLCG2)
04662 B cell receptor signaling pathway
108313460 (PLCG2)
04664 Fc epsilon RI signaling pathway
108313460 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
108313460 (PLCG2)
04670 Leukocyte transendothelial migration
108313460 (PLCG2)
04062 Chemokine signaling pathway
108313460 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
108313460 (PLCG2)
04919 Thyroid hormone signaling pathway
108313460 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
108313460 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
108313460 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
108313460 (PLCG2)
04380 Osteoclast differentiation
108313460 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108313460 (PLCG2)
05206 MicroRNAs in cancer
108313460 (PLCG2)
05205 Proteoglycans in cancer
108313460 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
108313460 (PLCG2)
05214 Glioma
108313460 (PLCG2)
05223 Non-small cell lung cancer
108313460 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
108313460 (PLCG2)
05171 Coronavirus disease - COVID-19
108313460 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
108313460 (PLCG2)
05169 Epstein-Barr virus infection
108313460 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
108313460 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108313460 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cimi04131
]
108313460 (PLCG2)
Enzymes [BR:
cimi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
108313460 (PLCG2)
Membrane trafficking [BR:
cimi04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
108313460 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
108313460 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
PH
PH_12
EF-hand_PLCG1
SH2_1
SH3_2
PH_14
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
108313460
NCBI-ProteinID:
XP_017397357
Ensembl:
ENSCCAG00000020986
UniProt:
A0A2K5PSJ7
LinkDB
All DBs
Position
Unknown
AA seq
1265 aa
AA seq
DB search
MSTMASVDSLAEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIVEIKEIRPGKNSKDFERAKAVRQKEDCCFTILYGNQFVLSTLSLAADSREDAV
NWLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSGA
KFLKDKFVEVGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGRPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKV
FKDVFGDLLLMKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEEVPQDIPPTELHFGEKWFHKKVEKR
TSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGTLKYY
LTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDML
MRIPRDGAFLIRRREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADVEELEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSIIRQKPVDLLKYNQKGLTRIYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKY
MQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKPGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKAIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSN
SKFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgtccaccatggccagtgtggattcccttgcggaatatgagaagagccagatcaagaga
gccctggagctggggacggtgatgactgtgttcagcttccgcaagtctacccctgagcga
aggaccgtccaggtgatcatggagacgaggcaggtggcctggagcaagaccgccgacaag
atcgagggcttcttggatatcgtggaaataaaagaaatccgcccagggaagaactccaaa
gatttcgagcgtgcaaaagcagttcgccagaaagaagactgctgcttcaccatcctatat
ggcaaccagttcgtcctcagcacactcagcttggcagctgactctagagaggatgcagtt
aactggctctctggcttgaaaatcttacaccaagaagcgatgaatgcgtccacacccacc
attatcgagagttggctgagaaagcagatatattctgtggatcaaaccagaagaaacagc
atcagcctccgagagttgaagaccatcttgccgttggtcaacttcaaagtgagcggtgcc
aagttccttaaagataagtttgtggaagtaggagcacacaaagatgagctgagctttgaa
cagttccatctcttctataaaaaacttatgtttgaacagcaaaaatcgattctcgatgaa
ttcaaaaaggattcgtctgtgttcatcctggggaacacggacaggccggatgcctctgct
gtttaccttcatgactttcagaggtttctcatacatgaacagcaggagcactgggctcag
gatctgaacaaagtccgtgagcggatgacaaagttcattgatgacaccatgcgtgaaacc
gctgagcctttcctgtttgtggatgagttcctcacatacctgttttcacgagaaaacagc
atctgggatgagaagtatgacgctgtggacatgcaggacatgaacaaccccctgtctcat
tactggatctcctcgtcacataacacgtacctcacaggtgaccagctgcggagtgagtcg
tccacagaggcctacatccgctgcctgcgcatgggctgtcgctgcatcgaactggactgc
tgggatgggcccgacggcaggccggtcatctaccacggctggacgcggaccaccaagatc
aagtttgatgacgtcgtgcaggccatcaaggaccacgcctttgtgacctcgagcttccca
gtgatcctgtccattgaggagcattgcagcgtggagcagcagcgccacatggccaaggtc
ttcaaagacgtatttggcgaccttcttctgatgaagcccacggaggccagcgctgaccag
ctgccctcacccagccagctgcgtgagaagatcatcatcaagcataagaagctgggcccc
cgaggtgacgtggatgtcaacgtggaggacaagaaggatgaacacaagcaacagggagag
ctgtacatgtgggattccatcgaccagaaatggactcggcactactgcgccatcgccgat
gccaagctgtccttcagtgatgacattgaacagactgtggaggaggaagtgccccaggat
atacccccaacagagctgcattttggggagaaatggttccacaagaaggtggagaagagg
acgagtgctgagaagttgctgcaggaatactgcatggagacagggggcaaggatggcacc
ttcctggttcgggagagcgagaccttccccaatgactacactctgtccttctggcggtca
ggccgggtccagcactgccggatacgctccaccatggagaatgggaccctgaagtactac
ctgactgacaacctcaccttcagcagcatctacgccctcatccagcactaccgcgagacg
cacctgcgctgtgccgaattcgagctgcggctcacggaccctgtgcccaaccccaacccc
cacgagtccaagccgtggtactatgacagcctgagtcgcggagaggcagaggacatgttg
atgaggatcccccgggatggggccttcctgatccggaggcgagagggcagcgactcctac
gccatcaccttcagggctaggggcaaggtgaagcattgtcgcatcaaccgggacggccgg
cactttgttctgggaacctccgcctattttgagagcctggtggagctcgtcagttactat
gagaagcattcactctaccgaaagatgagactgcgctaccccgtgacgcccgagctcctg
gagcgctacaatatggaaagagatataaactccctctatgatgtcagcagaatgtatgtg
gatcccagtgaaatcaatccgtccatgcctcagagaactgtgaaagctctgtatgactac
aaagccaagcgaagcgatgagctgagcttctgccgtggcgccctcatccacaatgtctcc
aaggagcccgggggctggtggaagggtgactatggaaccaggatccagcagtacttccca
tccaactacgtggaggacatctcaactgcagatgtcgaggagctggaaaagcagattatt
gaagacaatcccttagggtctctttgcagaggcatattggacctcaatacctataacgtc
gtgaaagccccacaggggaaaaaccagaagccctttgtcttcatcctggagcccaagaag
cagggcgatcctccggtggagtttgccacagacagggtggaggagctcttcgagtggttt
cagagcatccgagagatcacctggaagattgacaccaaggagaacaacatgaagtattgg
gagaagaaccagtccatcgccatcgagctctctgacctggttgtctactgcaaaccaacc
agcaaaaccaaggacaacttagaaaatcctgactttagagaaatccgctcctttgtggag
acaaaggccgacagcatcatcagacagaagcccgtcgacctcctcaagtacaatcaaaag
ggcctgacccgcatctacccaaagggacaaagagttgactcttccaactatgaccccttc
cgcctctggctgtgcggttctcagatggtggcactcaatttccagacggcagataagtac
atgcagatgaatcacgcgttgttttctctcaatgggcgcacgggctacgttctgcagcct
gagagcatgaggacagagaaatatgacccgatgccacctgagtcccagaggaagatcctg
atgaccctgactgtcaaggttctcggtgctcgccatctccccaaacctggacgaagtatt
gcctgtccctttgtagaggtggagatctgtggagctgagtatgacaacaacaagttcaaa
acgacggttgtgaatgataatggcctcagccctatctgggctccaacacaggagaaggtg
acatttgaaatttatgacccaaacctggcatttctgcgcttcgtggtttacgaagaagat
atgttcagtgatcccaactttcttgctcatgccacttaccccattaaagcaattaaatca
ggattcagatctgttcctctgaagaatgggtacagtgaggacatcgagctggcttccctc
ctggttttctgtgaaatgcggccagtcctggagagtgaagaggaactttactcctcctgt
cgccagctgaggaggcggcaagaagaactgaacaaccagctgtttctgtacgacacacac
cagaatttgcgcaatgccaaccgggatgccctggttaaagagttcaacgttaacgagaac
cagctccagttgtaccaggagaaatgcaacaggaggttgagagagaagagagtcagcaac
agcaagttttactcgtag
DBGET
integrated database retrieval system
