Clostridium intestinale: HZF06_00725
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Entry
HZF06_00725 CDS
T08934
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
cint
Clostridium intestinale
Pathway
cint00270
Cysteine and methionine metabolism
cint00480
Glutathione metabolism
cint01100
Metabolic pathways
cint01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
cint00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HZF06_00725 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
HZF06_00725 (gshAB)
Enzymes [BR:
cint01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
HZF06_00725 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATP-grasp_3
GARS_A
ATPgrasp_ST
Dala_Dala_lig_C
ATP-grasp_2
Motif
Other DBs
NCBI-ProteinID:
QLY80152
UniProt:
A0A7D6VVK9
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Position
152922..155264
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AA seq
780 aa
AA seq
DB search
MEGIDNKLLDFLVKENLSEDLFKGNFGIEKENVRVYKDGHLALTAHPAEFGDKLENAFIK
TDFSESQVEVVTPACKSLEEMYDFLENLQNIVSSTLKDEYLWTQSNPPILPSDGEIPIAC
YGEAGKVEREYREKLAEKYGRKKQLLSGIHFNFSFDEDFLRYLYREFSNSKDFKDFKSTI
YLRTVKNFLKYRWFLIYLTGASPVFHKSYMDSCVEISESLENETGYSENLVSLRNGICGY
KNKEDFPINYDSLSDYIESINELIRCNKIENASELYSPIRVKSIGGKNSLEILKSDGIKY
VEVRILDLNPLSKNGIFLEDLYLINIFLIYMLLKEDSQFNEKEQEISNINHNIVATLGRK
SDLTILNSKSEKVLLKDEALKIIYDMELLVRKLGIKEGFLLNIVSNAKGKILDSKQTYSY
KVLQGIKEKSYVDFHIDKAKEYLEETQKKNFNLIGYEDLELSTQILIKDSIKRGIEFKVL
DRKENFISLSFNGKTEYVKQATKTSKDSYSTVLVMENKVVTKEVLKENEVRVPSGENYNS
AEEAMKFYDKFENKKIVIKPKSTNFGIGISIFKDGFNRDDFRRALEIAFDNDNTVLVEEF
IEGKEYRFLVIDDEVVGILHRVPANVCGNGVNNISELVREKNKDSLRGKGYKTPLEKISL
GEIEDMFLKAQGKDFTYVPNKDEIVYLRENSNVSTGGDSIDYTDKIDQSYKEMAIKAAKA
VGASICGVDMMITNINEKISKDNYGIIELNFNPAIHIHCYPYKGKNRNVGEKVLNLIFKG
NT seq
2343 nt
NT seq
+upstream
nt +downstream
nt
atggaaggtattgataataaattactggattttttagttaaagaaaacttaagtgaagac
ttgtttaaaggtaattttggaatagagaaagaaaatgttagagtatataaagatggacac
ttagctttaaccgctcatccagcggagtttggagataaattagaaaatgcttttattaaa
acagatttttctgaaagtcaggtagaggtagtaacacctgcatgtaaaagcttagaggag
atgtatgactttttggagaatctccagaatatagtttctagtacattaaaagatgaatat
ctatggactcaaagcaatcctcctatattaccaagcgatggtgaaattccaatagcttgt
tatggagaggcaggtaaagttgagagagaatatagagagaagttagcagagaagtatggt
agaaagaaacaactattatcaggaatacattttaacttctcctttgatgaggatttttta
agatatctatatagagaatttagcaatagtaaagactttaaggattttaaaagcactata
tatttaagaacagtaaaaaatttcttgaaatatagatggtttctaatatatcttactgga
gcgagtccggtatttcataaaagttatatggatagttgcgtagaaattagtgaaagttta
gaaaatgaaactggctattcggaaaacctagtatcccttagaaatggaatatgtggatat
aaaaataaagaagattttcctattaattatgatagtttaagtgattatatagaaagtata
aacgaattaattcgctgtaataaaattgaaaatgcaagtgaattatatagtcctattagg
gttaaatcaataggtggtaagaattctttagaaatattaaaaagcgatggaataaagtac
gtagaagtcagaatattagatttaaatccattaagtaaaaatggaatatttctagaggat
ttatatttaataaatattttcttgatctatatgttgttaaaggaagatagccagtttaat
gaaaaagaacaggaaatttctaatataaatcataatatagtagcaacattaggaagaaag
tcagatttaacaatattaaatagtaagtctgaaaaagtgctgctaaaggatgaagcttta
aaaattatatatgatatggagcttttagttagaaaattagggattaaagaaggattttta
ttgaatatagtatctaatgctaagggaaaaatattagattcaaagcagacctattcttat
aaggttcttcaaggaataaaagaaaaatcatatgtagactttcatatagataaagctaaa
gaatatttagaagaaactcaaaaaaagaactttaatttaataggatatgaagatttagaa
ttatcaactcagatattaataaaggattctataaaaagaggtatagaatttaaagtacta
gatagaaaagagaattttataagtcttagctttaatggaaaaacagagtacgtaaagcaa
gctactaaaacttccaaagattcttatagtactgttcttgttatggaaaataaagtggtt
actaaggaagtattgaaagaaaatgaagttagagtacctagtggagaaaattataatagc
gcagaagaagctatgaagttctacgataagttcgagaataagaagatagttataaaacct
aaatctactaactttggtataggtatatctatatttaaggatggatttaatagagatgat
tttagaagagccctagaaatagcatttgataatgataatacggttttagtagaagaattt
atagaaggcaaagaatatagatttttagttatagatgatgaagtagtaggaatacttcac
agagtaccagccaatgtatgtggtaatggagtaaataatatatcggagctagttagggaa
aagaataaagatagtctaagaggaaagggatataaaacacctcttgaaaaaatatctcta
ggtgaaatagaagatatgttcttaaaagctcaaggtaaggactttacttatgtgccaaac
aaagacgagattgtatacttaagagaaaactctaatgttagtactggtggggacagtatt
gattatacagataagatagatcaaagctataaggaaatggctataaaagcagctaaagca
gtgggtgcatctatatgtggagtagatatgatgattactaacattaatgagaaaatatct
aaagataactatggaattatagagctaaactttaacccagctatacacattcattgctat
ccttacaaaggaaagaatagaaacgtaggggaaaaagttcttaatttaatattcaagggc
tag
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