Clostridium innocuum: G4D55_05675
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Entry
G4D55_05675 CDS
T06525
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ciu
Clostridium innocuum
Pathway
ciu00300
Lysine biosynthesis
ciu00550
Peptidoglycan biosynthesis
ciu01100
Metabolic pathways
ciu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ciu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
G4D55_05675
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
G4D55_05675
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
G4D55_05675
Enzymes [BR:
ciu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
G4D55_05675
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QIX08591
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Position
1167085..1168656
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AA seq
523 aa
AA seq
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MMLFCFLAVYLFFLYVPLKQSMHMFQQNRYNKGRYQTWLVSYIRLSWKLIVKILLTLMLS
YSLLLLQPTSMQEVLLLMLVAIFAYISCKMEEERVYRKPLVKTARIHRLAILLYTLYGIL
LCLLHYFLSAAALILVTPFLFLSAWLMVLPAAWISEPLEMAIRNHYAADAAKLLRSNNAL
SIVGITGSYGKTSVKTILNELLSDVYYTLMTPGSYNNQMGITLTIRNKLERLHEVFLCEM
GADHVKEIHDLMQFVKPQYGVVTSVGAQHLATFGSMENILHEKMQMIECLPADGIGFVNR
DNAYIRTYSIQNTCRIVWFGMSEDADYRCCDIRYSEEGTSFTVIQEGQSHRFHTKLLGKH
NVVNITCAIAVAHTLGVSWEIMALAVEKLPYIEHRLQVRKSFCTLLDDAYNSNPEGARCA
LEVLKQMKHQRFIITPGFLELGEQQEEEQYKLGEEIADSVDTAVLVGAVQTKSIAAGLAD
SGFPKERVHVCDSFQEALAIVQKQAQLQDCVLLENDLPDAFNH
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgatgctgttctgttttctggcggtgtatcttttttttctttatgttcctttgaagcag
tctatgcatatgttccagcagaaccgttacaacaaagggcggtatcagacatggctggtg
tcctatatccgcttatcctggaagctgattgtgaaaatactgctgacgctgatgctgagc
tacagccttcttttgctgcagccgacttccatgcaggaggttctgctgctgatgctggtt
gctatctttgcctacatcagctgtaaaatggaggaggagcgcgtctatcgcaagccgctg
gtgaaaacagcgcgaattcaccgccttgcgatcctgctgtatacgttatacggcattttg
ctgtgcctgctgcattatttcctgtctgctgcagcgctcattcttgtgacaccgtttctt
tttctgtccgcatggctcatggtgctacctgccgcatggatttcagagccgctggaaatg
gcgattcgcaatcattatgcagcggatgccgcaaagctgttaagaagcaacaacgcgctg
tccattgtcggcatcaccggaagctatgggaaaacgagtgtgaaaaccattctgaatgag
ctcttgtcagatgtttactataccctgatgacgcccggctcctataataatcagatggga
atcactctcaccatacgcaataagctggaacggctgcatgaggtgtttttatgtgaaatg
ggagcggatcatgtgaaggaaattcatgatctgatgcagtttgtaaagccgcagtatggt
gttgtgacctctgtcggcgcacagcatctggcaacgtttggctccatggaaaatatactc
catgagaaaatgcagatgatagaatgtcttcctgccgacggtatcggcttcgtgaatcgg
gacaatgcctatattcgtacctacagtattcaaaacacctgccgaatcgtatggttcggg
atgagcgaggatgcggattatcgctgctgtgatatccgttacagtgaggaaggcacgtcg
tttacggtgatacaggaggggcagtcccaccggtttcacacaaagcttttaggaaaacac
aatgtcgtgaacatcacctgtgccatcgcagttgcgcacacacttggtgtttcctgggaa
ataatggcgttagctgtcgaaaagctgccctatatcgagcatcggctgcaggtacggaaa
agcttttgcaccctgctggatgacgcctataattccaatccggaaggagcgcgctgtgca
ctggaggttttaaagcagatgaagcatcagcggtttatcatcacacccggttttctggag
ctgggagaacagcaggaggaagaacagtacaagctgggtgaagagattgcggatagcgtg
gatacggcggtattggtaggtgctgtccagacgaaaagcatcgccgcaggattggcagac
agcggatttccaaaagaaagggtccatgtttgcgacagctttcaggaggcactggcaatc
gtacaaaagcaggcacagctgcaggactgcgtgctgctggaaaatgatttgccggatgca
ttcaaccactag
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