| Entry |
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| Symbol |
PDE8B
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| Name |
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X5
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| KO |
| K18437 | high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53] |
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| Organism |
cjc Callithrix jacchus (white-tufted-ear marmoset)
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| Pathway |
| cjc04927 | Cortisol synthesis and secretion |
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| Brite |
KEGG Orthology (KO) [BR:cjc00001]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100386134 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
100386134 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100386134 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100386134 (PDE8B)
Enzymes [BR:cjc01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
100386134 (PDE8B)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
2:complement(130431749..130777840)
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| AA seq |
1118 aa
MSVEETRPLDSGGGGDGAEARCQLPCTGAPRRIRAAGTLCPVPRARGAAGGAEGRSGARA
AAAPEPGHLRRKEGGSEGGRGRAQTESGERRCRRAGERAGALAQGRGCGSPARSSWAAAG
AVPREEGKAEARGACLGRRGGEVSGRRCARGAVCARSPARGGRWPKRESWGDARCPWRLG
GGHRGQPDGGADAQAGGRAVRALPRPPTHCRWQPVRWVPAAAGAGGRAGEPGRGMGCAPS
IHVSQSGVIYCRDSDESNSPHQTTSVSQGPAAPLPGLFVQTDAADAIPPSRASGPPSAAR
VRRARAELGSGSSAGSAAPAATTSRGRRRHCCSSAEAETQTSYTSVKVSSAEVRIGPMRL
TQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIVIDHRQT
QNFDAEAVCRSIRATNPSEHTVILAVVSRVSDDHEEASVLPLLHAGFNRRFMENSSIIAC
YNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGYHKG
ELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQ
GGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTEPHSFRYKNRRKESIDVKSISSRG
SDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTEL
YSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITINDVPPCI
SQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFTRFGVCEFLNCSETTLRAWFQVIEAN
YHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPGRTNSFL
CNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLAT
EMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCR
PLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDA
WDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS |
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| NT seq |
3357 nt +upstreamnt +downstreamnt
atgagtgtagaagagacgaggcctctggacagcggaggaggaggggacggcgccgaggcg
cggtgccagctgccgtgcacaggggccccgcggcggatccgagccgcgggcacgctctgc
ccagtcccgagagctcggggagctgcgggaggggcggaggggcgcagtggggcccgggcg
gctgcggccccggagcctgggcacctgaggaggaaggagggtgggagtgagggagggagg
ggacgggctcagaccgaaagtggggaaagaaggtgcaggcgggcgggcgagagggcaggc
gccctggcccagggccgcgggtgcgggagcccggcgaggtcaagctgggcggcggcgggg
gccgtgccgagggaggaggggaaggcggaggcgcggggagcgtgtttggggcgccgcggc
ggggaggttagcggccgccggtgcgcgcggggcgctgtgtgtgcgcgctcccccgctcgg
ggaggaagatggcccaaaagggaaagttggggtgacgctcgctgtccctggaggctcggc
ggggggcatcgcggccagcccgacggaggggcggacgcacaggccggggggcgcgcagtc
cgggcgctgccgcggccgcccactcactgcaggtggcagccggtgcgctgggtcccggcg
gccgcgggcgcaggcgggcgcgcgggggagcccggccgagggatgggctgcgcccccagc
atccatgtctcgcagagcggcgtgatctactgccgggactcggacgagtccaactcgccc
caccagaccaccagcgtgtcgcagggccccgcggcacccctgcctggcctcttcgtccag
accgacgccgccgacgccatccccccgagccgcgcatcgggaccccccagcgccgcccgc
gtccgcagggcccgcgccgagctgggcagcggcagcagcgcaggttccgcagcccccgcc
gcgaccaccagcaggggccggaggcgccactgctgcagcagcgccgaggccgagactcag
accagctacaccagcgtgaaggtgtcttctgcggaggtgcgcatcgggcccatgagactg
acgcaggaccctattcaggttttgctgatctttgcaaaggaagatagtcagagtgatggc
ttctggtgggcctgtgacagagctggttatagatgcaatattgctcggactccggagtca
gcccttgaatgctttcttgataagcatcatgaaattattgtaattgatcatagacaaact
cagaacttcgatgcagaagcggtgtgcaggtcaatccgggccacaaatccctccgagcac
acagtgatcctcgcagtggtttcacgagtatcggatgaccatgaagaggcctcagtcctt
cctcttctccacgcaggcttcaacaggagatttatggagaatagcagcataattgcttgc
tataatgaactgattcaaatagaacatggggaagttcgctctcagttcaaattaagggcc
tgtaattcagtgtttacagcattagaccactgtcatgaagccatagaaataacaagcgat
gaccacgtgattcagtatgtcaacccagccttcgaaaggatgatgggctaccacaaaggt
gagctcctgggaaaagaactcgctgatctgcccaaaagcgataagaaccgggcagacctt
ctcgacaccatcaatacatgcatcaagaagggaaaggagtggcagggggtttactatgcc
agacggaaatccggggacagcattcaacagcacgtgaagatcaccccagtgattggccaa
ggagggaaaattaggcattttgtctccctcaagaaactgtgttgtaccactgacaataat
aagcagattcacaagattcatcgtgattcaggagacaattctcagacagagcctcattca
ttcagatataagaacaggaggaaagagtccattgacgtgaaatcgatatcatctcgaggc
agtgatgcaccaagccttcagaatcgtcgctacccgtctatggcgaggatccactccatg
accatcgaggctcccatcacaaaggttatcaatataatcaatgcagcccaagaaaacagc
ccagtcacagtagcagaagccttggacagagttctagagattttacggaccacagaactg
tactcccctcagctgggtaccaaagatgaagatccccataccagtgatcttgttggaggc
ctgatgactgacggcttgagaaggctgtcaggaaacgagtatgtgttcacaaagaatgtg
caccagagccacagtcacctggcgatgccaataaccatcaatgatgttcccccttgtatc
tctcaattacttgataatgaggagagttgggacttcaacatctttgaattggaagccgtt
acacataaaaggccgttggtttacctgggcttaaaggttttcactcggtttggagtatgt
gaatttttaaactgttctgaaaccactcttcgggcctggttccaagtgattgaagccaac
taccactcttccaatgcctaccacaactccacccatgctgccgacgtactgcatgccacc
gctttcttccttggaaaggaaagagtaaagggaagcctcgatcagctggatgaggtggca
gccctcattgctgccacggtccatgacgtggatcacccaggaaggaccaactctttcctc
tgcaatgcaggcagcgagcttgctgtgctctataatgacactgcggttctggagagccac
cacactgccctggccttccagctcacagtcaaggacaccaagtgcaacattttcaagaat
attgacaggaaccattatcgaacgctgcgccaggctattattgacatggttttggcaaca
gaaatgacaaaacactttgaacatgtgaataagtttgtgaacagcatcaacaagccaatg
gcagctgagattgagggcagcgactgtgaatgcaaccctgctgggaagaacttccctgaa
aaccaaatcctgatcaaacgcatgatgattaagtgtgctgacgtggccaacccatgccgc
cccttggacctgtgcattgaatgggctgggaggatctctgaggagtattttgcacagact
gatgaagagaagagacaggggctccctgtggtgatgccagtgtttgaccggaatacctgt
agcatccccaagtctcagatatctttcattgactacttcataacagacatgtttgatgca
tgggatgcctttgcacatctgccagccctgatgcaacatctggctgacaactacaaacac
tggaagacactagatgacctaaagtgcaaaagtctgaggcttccatctgacagctaa |
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