Entry |
|
Symbol |
SRC
|
Name |
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
|
KO |
|
Organism |
cjc Callithrix jacchus (white-tufted-ear marmoset)
|
Pathway |
cjc01521 | EGFR tyrosine kinase inhibitor resistance |
cjc04613 | Neutrophil extracellular trap formation |
cjc04625 | C-type lectin receptor signaling pathway |
cjc04750 | Inflammatory mediator regulation of TRP channels |
cjc04810 | Regulation of actin cytoskeleton |
cjc04919 | Thyroid hormone signaling pathway |
cjc05100 | Bacterial invasion of epithelial cells |
cjc05163 | Human cytomegalovirus infection |
cjc05167 | Kaposi sarcoma-associated herpesvirus infection |
cjc05168 | Herpes simplex virus 1 infection |
cjc05207 | Chemical carcinogenesis - receptor activation |
cjc05208 | Chemical carcinogenesis - reactive oxygen species |
cjc05418 | Fluid shear stress and atherosclerosis |
|
Brite |
KEGG Orthology (KO) [BR:cjc00001]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100386165 (SRC)
04015 Rap1 signaling pathway
100386165 (SRC)
04370 VEGF signaling pathway
100386165 (SRC)
09133 Signaling molecules and interaction
04081 Hormone signaling
100386165 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100386165 (SRC)
04137 Mitophagy - animal
100386165 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100386165 (SRC)
04520 Adherens junction
100386165 (SRC)
04530 Tight junction
100386165 (SRC)
04540 Gap junction
100386165 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100386165 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100386165 (SRC)
04613 Neutrophil extracellular trap formation
100386165 (SRC)
04625 C-type lectin receptor signaling pathway
100386165 (SRC)
04062 Chemokine signaling pathway
100386165 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
100386165 (SRC)
04915 Estrogen signaling pathway
100386165 (SRC)
04917 Prolactin signaling pathway
100386165 (SRC)
04921 Oxytocin signaling pathway
100386165 (SRC)
04926 Relaxin signaling pathway
100386165 (SRC)
04919 Thyroid hormone signaling pathway
100386165 (SRC)
09156 Nervous system
04727 GABAergic synapse
100386165 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100386165 (SRC)
09158 Development and regeneration
04360 Axon guidance
100386165 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100386165 (SRC)
05207 Chemical carcinogenesis - receptor activation
100386165 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
100386165 (SRC)
05203 Viral carcinogenesis
100386165 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
100386165 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
100386165 (SRC)
05168 Herpes simplex virus 1 infection
100386165 (SRC)
05163 Human cytomegalovirus infection
100386165 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
100386165 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
100386165 (SRC)
05152 Tuberculosis
100386165 (SRC)
05100 Bacterial invasion of epithelial cells
100386165 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100386165 (SRC)
05418 Fluid shear stress and atherosclerosis
100386165 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100386165 (SRC)
01522 Endocrine resistance
100386165 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:cjc01001]
100386165 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:cjc04131]
100386165 (SRC)
Enzymes [BR:cjc01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100386165 (SRC)
Protein kinases [BR:cjc01001]
Non-receptor tyrosine kinases
SRC family
100386165 (SRC)
Membrane trafficking [BR:cjc04131]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
100386165 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
100386165 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
100386165 (SRC)
Macropinocytosis
Kinases
100386165 (SRC)
|
SSDB |
|
Motif |
|
Other DBs |
|
LinkDB |
|
Position |
5:30780052..30840399
|
AA seq |
553 aa
MGSNKSKPKDASQRRRSLEPSENAHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL |
NT seq |
1662 nt +upstreamnt +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccagcggcgccgcagcctggagccc
tccgagaacgcgcacggagccggcgggggcgctttccccgcttcgcagacccccagcaag
ccagcctcggccgacggccaccgcggtcccagcgcggccttcgcccccgcggccgccgag
cccaagctgttcggaggcttcaactcctcggacaccgtcacctccccgcagagggcgggc
ccgctggccggtggagtgaccacctttgtggccctctatgactatgagtctaggacggag
acagacctgtccttcaagaaaggcgagcggctccagatcgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggagactggtggctg
gcccactcgctcagcacgggacagacaggctacatccccagcaactacgtggcaccctcc
gactccatccaggctgaagagtggtattttggcaagatcaccaggcgggagtcagagcgg
ctactgctcaacgcggagaacccgagggggacattcctagtgcgggaaagtgagaccacg
aaaggtgcttactgcctctcagtgtccgacttcgacaacgccaagggcctcaacgtgaag
cactacaagatccgcaagctggacagcggcggcttctatattacctcccgcacccagttc
aacagtctgcagcagctggtggcctactactccaaacatgccgacggcctgtgccaccgc
ctcaccactgtgtgccccacgtctaagccacagactcaaggcctggccaaggatgcctgg
gagatccctcgggagtcactgcggctggaggtcaagctgggccagggctgctttggcgag
gtgtggatgggaacctggaatggcaccaccagggtggccatcaaaaccctgaagcctggc
accatgtctccggaggccttcctgcaggaggcccaggtcatgaagaaactgaggcatgag
aagctggtgcagctgtacgccgtggtttcggaggagcccatctacattgtcacggagtac
atgagcaaggggagtttgctggactttctcaagggggaaacgggcaagtacctgcggctg
cctcagctggtggacatggctgctcagatcgcctctggcatggcatatgttgagcggatg
aactacgtccatcgggaccttcgtgcagccaacatcctggtgggagagaacttggtgtgc
aaagtggccgacttcgggctggctcggctcatcgaagacaatgagtacacagcccggcaa
ggtgccaaattccccatcaagtggacggctccggaagctgccctctatggccggttcacc
atcaagtcggatgtgtggtccttcgggatcctgctgacggagctcaccacaaaggggcgg
gtgccctaccctgggatggtgaaccgagaggtgctggaccaggtggagcggggctaccgg
atgccctgcccgcccgagtgtcctgagtccctgcacgacctcatgtgccagtgctggcgg
aaagagcctgaggagcggcccactttcgagtacctgcaggcctttctggaggactacttc
acgtccactgagccccagtaccagcctggagagaacctctag |