| Entry |
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| Symbol |
NLRP3
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| Name |
(RefSeq) NACHT, LRR and PYD domains-containing protein 3 isoform X1
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| KO |
| K12800 | NACHT, LRR and PYD domains-containing protein 3 |
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| Organism |
cjc Callithrix jacchus (white-tufted-ear marmoset)
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| Pathway |
| cjc04621 | NOD-like receptor signaling pathway |
| cjc04625 | C-type lectin receptor signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:cjc00001]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100392399 (NLRP3)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
100392399 (NLRP3)
04623 Cytosolic DNA-sensing pathway
100392399 (NLRP3)
04625 C-type lectin receptor signaling pathway
100392399 (NLRP3)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
100392399 (NLRP3)
05164 Influenza A
100392399 (NLRP3)
09171 Infectious disease: bacterial
05132 Salmonella infection
100392399 (NLRP3)
05135 Yersinia infection
100392399 (NLRP3)
05133 Pertussis
100392399 (NLRP3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100392399 (NLRP3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:cjc04131]
100392399 (NLRP3)
09183 Protein families: signaling and cellular processes
04054 Pattern recognition receptors [BR:cjc04054]
100392399 (NLRP3)
Membrane trafficking [BR:cjc04131]
Autophagy
Other autophagy associated proteins
TRIM-directed selective autophagy
100392399 (NLRP3)
Pattern recognition receptors [BR:cjc04054]
Cytoplasmic pattern recognition receptors
NOD-like receptors
100392399 (NLRP3)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
19:complement(34517956..34546912)
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| AA seq |
1034 aa
MKMASTRCKLARYLEDLEDVDFKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWDNACASNHTVICQQDSIEEEWMGLLG
YLSRISICKKKKDYGKKYRRHVRSRFQCIEDRNARLGESVSLNKRYTPLRLIKEHRSQQE
REQELLTIGRTKAGDSPVSPIKMESLFEPDAEHAEPVHTVVFQGAAGIGKTILARKIMLD
WASGTLYQDRFDYLFYIHCRELSLVTQRSLGDLIMSCCPDPNPPIHRIVRKPSRILFLMD
GFDELQGAFDEHIGPLCTDWRKAERGDILLSSLIRKKLLPEAFLLITTRPVALEKLQHLL
DHPRHVEILGFSETKRKEYFFKYFSDEAQAREAFSLIQENEVLFTMCFIPLVCWIVCTGL
KQQMESGKSLAQTSKTTTAVYIFFLSSLLQPRGGSQEHTLSAHLWGLCSLAADGIWNQKI
LFEESDLRNHGLQKAEVSAFLRMNLFQKEVDCEKLYSFIHMTFQEFFAAMYYLLEEEKEG
GTQNVPGSCLTLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKVS
QQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDHFPKIEINLSTRM
DHVVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDVAQCVPPGSLTACSLGLVN
SHFTSGFCRGLFSVLSTNQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGL
SHECCLDLSLVLSSSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSA
CCQDVASVLSTNHSLTRLYMGENTLGDAGVEILCEKAKNPQCHLQKLGLVNSGLTSACCS
ALSSVLSTNGNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDSCSLTSHCCWDLS
TLLTSSRSLRKLSLGNNDLGDLGVMMFCEVLRQQSCLLQNLGLCEMFFNYETKRALETLQ
EEKPELTIVFEPSW |
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| NT seq |
3105 nt +upstreamnt +downstreamnt
atgaagatggcaagcacccgctgcaagctggccaggtacttggaggacctggaggatgta
gacttcaagaaatttaagatgcacctagaagactatcctcctcaaaagggctgcatccca
ctcccgaggggtcagaccgagaaggcagaccacgtggatctagccacgctgatgattgac
ttcaatggggaggagaaggcgtgggccatggccgtgtggatcttcgctgcgatcaacagg
agagacctttatgagaaggcaaaaagagatgagcccaaatgggataatgcatgtgcttct
aatcacactgtgatatgccagcaagacagcattgaagaggagtggatgggtttgctgggt
tacctttccagaatctccatttgtaaaaagaagaaagattacggtaagaagtacagaaga
catgtgagaagcagattccagtgcatcgaagacaggaacgcccgtctgggtgagagtgtg
agcctcaacaaacgctacacaccactgcgcctcatcaaggagcaccgcagccagcaggag
agggagcaggagcttctgaccatcggcaggactaaggcaggggacagccccgtgagtccc
attaagatggaatcgctgtttgagcctgatgcggagcacgcggagcctgtgcacacagtg
gtattccagggagccgcggggattgggaaaactatactggccaggaagattatgttggac
tgggcgtcggggacactctatcaagacaggtttgactatttgttctatatccactgtcgg
gagttgagcctcgtgacgcagaggagcctgggggacctgatcatgagctgctgccccgac
ccaaacccccccatccacaggatcgtgaggaagccctccagaatcctcttcctcatggac
ggctttgatgagctgcagggtgcctttgatgagcacatcgggccactctgcaccgactgg
cggaaggccgagcggggagacattctcctgagcagcctcatcagaaagaagctgctcccc
gaggccttcctgctcatcaccacgagaccggtggccctggagaagctgcagcacttgctg
gaccaccctcggcatgtggagatcctgggtttctcggagaccaaaaggaaggagtatttc
ttcaagtacttctcagatgaggcccaggcgagggaagccttcagtctgattcaggagaac
gaggtcctcttcaccatgtgtttcattcccctcgtctgctggattgtgtgcaccggcctg
aagcagcagatggagagtggcaagagcctggcccagacatccaagactaccactgcggtg
tacatcttcttcctctccagtttgctgcagccccgaggagggagccaggagcataccctc
tctgcccacctctgggggctctgctctttggctgcagacgggatctggaaccagaaaatc
ctctttgaggagtccgacctcaggaatcacggcctgcagaaggcggaggtgtctgctttc
ctgaggatgaacctgttccaaaaggaagtggactgcgagaagctctacagcttcatccac
atgaccttccaggagttctttgctgccatgtactacctgctggaagaggaaaaggaagga
gggacgcagaatgttccagggagttgcttgacgcttcccagccgggacgtgacagtcctt
ctggaaaactacggcaaattcgagaaggggtatttgattttcgttgtgcgtttcctcttc
ggcctggtgaaccaggagaggacctcctacttggagaagaaattaagttgcaaggtctct
cagcagatcaggctggagctgctgaaatggattgaggtgaaggccaaggcaaagaagctg
cagatccagcccagccagctggaattgttctactgtttgtacgagatgcaggaggaggac
tttgtgcagagggccatggaccatttccccaagattgagatcaatctctccaccagaatg
gaccacgtggtttcttccttttgcattgagaactgtcatcgggtggagtccctttccctg
gggtttctccacaacatgcccaaggaggaggaggaagaggagaaggaaggccgacacctc
gacgtggcccagtgtgtacccccaggctctctcactgcctgttccctcgggctggtgaac
agccatttcacttccggcttctgtcggggcctcttctcggttctaagcaccaaccagagt
ctgactgaactggacctgagcgacaattctctgggggacccagggatgagagtgttgtgt
gaaacgctgcagcatcctggctgtaatattcggagattgtggttggggcgatgtggcctc
tcccatgagtgctgcctcgacctctccttggtcctcagcagtagccagaagctggtggag
ttggacctgagcgacaatgccctgggggactttgggatcagactcttgtgcgtgggactg
aagcatctactgtgcaacctgaagaagctctggctggtcagctgctgcctcacgtcagca
tgttgtcaggatgtggcatccgtactgagcaccaaccattccctgaccaggctctacatg
ggggagaacactctcggagacgcaggagtagaaattttgtgtgaaaaagccaagaatcca
cagtgtcacctgcagaaactggggttggtaaattctggcctcacatcagcctgttgttca
gctttgtcctcggtactcagcactaatgggaatctcacgcacctttacctgcgaggcaac
actcttggagacaaggggatcaagctcctctgtgagggactcttgcaccccgactgcaag
ctgcaggtgttggaattagacagctgcagcctcacgtcgcactgctgctgggatctttcc
actcttctgacctccagccggagcctgcgaaagctgagcctgggcaacaacgacctgggc
gacctgggggtgatgatgttctgtgaagttctgagacagcagagctgcctcctgcagaac
ctggggttgtgtgaaatgtttttcaattatgagacaaaacgtgcattagaaacacttcaa
gaagaaaagcctgagctgaccattgtctttgagccctcttggtag |
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