Entry
Symbol
MGST1
Name
(RefSeq) microsomal glutathione S-transferase 1 isoform X1
KO
Organism
cjc Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc00980 Metabolism of xenobiotics by cytochrome P450
cjc00982 Drug metabolism - cytochrome P450
cjc00983 Drug metabolism - other enzymes
cjc05204 Chemical carcinogenesis - DNA adducts
cjc05207 Chemical carcinogenesis - receptor activation
cjc05208 Chemical carcinogenesis - reactive oxygen species
cjc05418 Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cjc00001 ]
09100 Metabolism
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100392584 (MGST1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
100392584 (MGST1)
00982 Drug metabolism - cytochrome P450
100392584 (MGST1)
00983 Drug metabolism - other enzymes
100392584 (MGST1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100392584 (MGST1)
05204 Chemical carcinogenesis - DNA adducts
100392584 (MGST1)
05207 Chemical carcinogenesis - receptor activation
100392584 (MGST1)
05208 Chemical carcinogenesis - reactive oxygen species
100392584 (MGST1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100392584 (MGST1)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100392584 (MGST1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100392584 (MGST1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:cjc02000 ]
100392584 (MGST1)
Enzymes [BR:cjc01000 ]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.18 glutathione transferase
100392584 (MGST1)
Transporters [BR:cjc02000 ]
Other transporters
Pores ion channels [TC:1 ]
100392584 (MGST1)
BRITE hierarchy
SSDB
Ortholog Paralog Gene cluster GFIT
Motif
Motif
Other DBs
LinkDB
All DBs
Position
9:complement(5003938..5061078)
Genome browser
AA seq
155 aa AA seq DB search
MVDLSQLTDDEVFRAFASYATIILSKMMLMSAATAFYRMTRKVFANPEDCATFGKGENAK
KFLRTDDRVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTAVLHFRIFVGARIYHTIA
YLTPLPQPNRALGFFVGYGVTLSMAYRLLKSRLYL
NT seq
468 nt NT seq +upstream nt +downstream nt
atggttgacctttcccagctaacggacgatgaagtgttcagggcttttgcctcctatgca
acaattattctttcaaaaatgatgcttatgagcgctgcgactgcgttctatagaatgacg
agaaaggtttttgccaacccagaagactgtgcaacatttggcaagggagaaaacgccaag
aagtttcttcgaacagatgacagagtagaacgcgtacgcagggctcaccttaacgacctt
gaaaacattgttccgtttctgggaatcgggcttctgtattccctgagtggtcccgacctc
tccacagccgttctgcacttcagaatctttgtcggagcacggatctaccacaccatcgcg
tacctgacaccccttccccagccaaacagagctttgggtttttttgttggatatggggtt
actctttccatggcttacaggttgctgaaaagtagattgtacctgtga