| Entry |
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| Symbol |
TOP2B
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| Name |
(RefSeq) DNA topoisomerase 2-beta isoform X2
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| KO |
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| Organism |
cjc Callithrix jacchus (white-tufted-ear marmoset)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:cjc00001]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100396004 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:cjc03032]
100396004 (TOP2B)
03036 Chromosome and associated proteins [BR:cjc03036]
100396004 (TOP2B)
Enzymes [BR:cjc01000]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100396004 (TOP2B)
DNA replication proteins [BR:cjc03032]
Eukaryotic type
DNA Topoisomerases
100396004 (TOP2B)
Chromosome and associated proteins [BR:cjc03036]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100396004 (TOP2B)
Centrosome formation proteins
Centriole proteins
100396004 (TOP2B)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
17:complement(57096675..57165438)
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| AA seq |
1620 aa
MAKSGGCGAGAGVGGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL
LRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC
IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG
YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS
KFKMEKLDKDIVALMTKRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV
ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK
NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN
CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS
AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD
AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK
QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE
DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI
LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL
MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDN
LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLD
PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML
NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD
HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT
IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEDTQNQHDDSSSDSGTPSGPDFNY
ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQERE
DILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDL
DTAAVKVEFDEEFSGVPVEGAGEEALTPSMPINKGPKPKREKKEPGTRVRKTPTSSGKPT
AKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD
DDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGN
LFSFPSYSQKSEDDSAKFDSNEEDTASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTAPK
PKRAPKQKKIVETVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSK
TTSKKPKKTSFDQDSDVDIFPSDFPSEPPSLPRTGRARKEVKYFAESDEEEDDVDFAMFN |
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| NT seq |
4863 nt +upstreamnt +downstreamnt
atggccaagtcgggtggctgcggcgcgggagccggcgtgggcggcggcaacggggcactg
acttgggtgaacaatgctgcaaaaaaagaagagtcagaaactgccaacaaaaatgattct
tcaaagaagttgtctgttgagagagtatatcagaagaagacacaacttgaacacattctt
cttcgtcctgatacatatattggatcagtggagccattgacacagttaatgtgggtgtat
gatgaagatgtgggaatgaattgcagagaggttacctttgtgccaggtttatataagatc
tttgatgaaattttggttaatgctgctgacaataaacagagggataagaacatgacttgt
attaaagtttctattgatcctgaatctaacattataagcatttggaataatgggaaaggc
attccagtagtagaacacaaggtagagaaagtttatgttcctgctttaatttttggacag
cttttaacatccagtaactatgatgatgatgaaaaaaaagttacaggtggtcgtaatggt
tatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaacagcttgcaaa
gaatataaacacagttttaagcagacatggatgaataatatgatgaagacttctgaagcc
aaaattaaacattttgatggtgaagattacacatgcataacattccaaccagatctgtcc
aaatttaagatggaaaaacttgacaaggatattgtggccctcatgaccaagagggcatat
gatttggctggttcatgtaaaggggtcaaggtcatgtttaatggaaagaaattgcctgta
aatggatttcgcagttatgtagatctttatgtaaaagacaaattggatgaaactggggtg
gccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctcacattgagt
gaaaaaggattccagcaaatcagctttgtaaatagtattgcaactacaaaaggtggacgg
cacgtggattatgtggtagatcaagttgttggtaaactgattgaagtagttaagaaaaag
aacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccatatatgggtttttatt
aattgccttattgaaaatccaacttttgattctcagactaaggaaaacatgactctgcag
cccaaaagttttgggtctaaatgccagctttcagaaaaattttttaaagcagcctctaat
tgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcagactcagctgaat
aagaaatgttcatcagtaaaatacagtaaaatcaaaggtattcccaaactggatgatgct
aatgatgctggtggcaaacattccctggagtgtacacttatattaactgagggagactcc
gccaaatcactggctgtgtctggattaggtgtgattggccgagacagatatggagttttt
ccactcaggggcaaaattcttaatgtacgggaagcttctcataaacagatcatggaaaat
gcagaaataaataatattattaaaatagttggtctacaatataagaaaagttacgatgat
gcagaatctctgaaaacgttacgctatgggaagattatgattatgactgatcaggatcaa
gatggttctcacataaaaggcctgcttattaatttcatccatcacaattggccatcactt
ctgaagcatggttttctcgaagagttcattactcctattgtaaaggcaagcaaaaataag
caggaactttccttctatagtattcctgaatttgatgagtggaaaaaacacatagaaaat
cagaaagcctggaaaataaagtactataaaggattgggtactagtacagctaaagaagca
aaggaatattttgctgatatggaaaggcatcgaatcttgtttagatacgctggtcctgaa
gatgatgctgccattacattggcattcagtaagaagaagattgatgacagaaaagaatgg
ttaacaaattttatggaagaccggagacagcgtaggttacatggcttaccagagcaattt
ttatatggtactgcaacaaagcatttgacttacaatgatttcatcaacaaggaattgatt
ctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggctttaaacct
ggccaacggaaagttttatttacctgtttcaagaggaatgataaacgtgaagtgaaagtt
gcccagttggctggatctgttgctgagatgtctgcttatcatcatggagaacaagcattg
atgatgactattgtgaatttggctcagaactttgtgggaagtaacaatattaacttactt
cagcctattggtcaatttggaactcggcttcatggtggcaaagatgctgcaagccctcgt
tatattttcacaatgttaagctctttagcaagactactttttcctgctgtggatgacaac
ctgcttaagtttctttatgatgataatcaacgtgtagagcctgagtggtatattcctata
attcccatggttttaataaatggtgctgagggcattggtactggatgggcttgtaaacta
cccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggcttggat
cctcatcccatgcttccaaactacaaaaactttaaaggcacaatccaagaacttggtcaa
aaccagtatgcggtcagtggtgaaatatttgtagtggacagaaacacagtagaaattaca
gagcttccggttagaacttggacacaggtatataaagaacaggttttagaacctatgcta
aatggaacagataaaacaccagcattaatttctgattataaagaatatcatactgacaca
actgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagcagaagctgctgga
ttgcataaagtttttaaacttcaaactactcttacctgtaattccatggtactctttgat
catatgggatgtctgaagaaatatgaaactgtgcaagacattctgaaagaattctttgat
ttacgattaagttattatggtttacgtaaggagtggcttgtgggaatgttgggagcagaa
tctacaaagcttaacaatcaagcccgtttcattttagagaagatacaagggaaaattact
atagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaatct
gacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaagacacacaa
aaccaacatgatgatagttcctccgattcaggaactccttcaggcccagattttaattat
attttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactgattaaacag
agagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctccttcagatctttgg
aaagaagatttagcagcatttgttgaagaactggataaagtggaagctcaagaacgagaa
gatattctggctggaatgtctggaaaagcaattaaaggtaaagttggcaaacccaaggtg
aagaaacttcaattggaagagacaatgccctcaccttatggcagaagaataattcctgaa
attacagctatgaaggcagatgccagcaaaaagttgctgaagaagaagaagggtgatctt
gatactgcagcagtgaaagtggaatttgatgaagaattcagtggagtgccagtagaaggt
gcaggagaagaggcattgactccgtcaatgcctataaataaaggtcccaaacccaaaagg
gagaaaaaggagcctggtaccagagtgagaaaaacacctacatcatctggtaaacctact
gcaaagaaagtgaagaagcggaatccttggtcagatgatgaatccaagtcagaaagtgat
ttggaagaaacagaacctgtggttattccaagagattctttgcttaggagagcagccgct
gaaagacctaaatacacatttgatttctcagaagaagaggatgatgatgctgatgatgat
gatgataataatgatttagaggaactgaaagttaaagcatctcccataacaaatgatggg
gaagatgaatttgttccttcagatggcttggataaagatgaatatacattttcaccaggc
aaatcaaaagctactccagaaaaatctttgcatgacaaaaaaagtcaggattttggaaat
ctcttctcatttccttcatattctcagaagtcagaagatgattcagctaaatttgacagt
aatgaagaagatactgcttctgttttttcaccgtcatttggtctgaaacagacagacaaa
gttccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagatacagcgcctaag
cccaagagagcccccaagcagaagaaaatagtagagactgtaaactctgactccgattca
gaatttggcattccaaagaagactacaacaccaaaaggtaaaggccgaggggcaaagaaa
aggaaagcatctggttctgaaaatgaaggtgattacaaccctggcaggaaaacatccaaa
acaacaagcaagaaaccgaagaaaacatcttttgatcaggattccgatgtggacatcttc
ccctctgacttcccttctgagccaccttctctgccacgaaccggtcgggctaggaaagaa
gttaagtactttgcagagtctgatgaagaagaagatgacgttgattttgcaatgttcaat
taa |
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