KEGG   Callithrix jacchus (white-tufted-ear marmoset): 100400572
Entry
100400572         CDS       T03264                                 
Symbol
CYP17A1
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase precursor
  KO
K00512  steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
Organism
cjc  Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc00140  Steroid hormone biosynthesis
cjc01100  Metabolic pathways
cjc04913  Ovarian steroidogenesis
cjc04917  Prolactin signaling pathway
cjc04927  Cortisol synthesis and secretion
cjc04934  Cushing syndrome
Module
cjc_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
cjc_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
cjc_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
cjc_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:cjc00001]
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    100400572 (CYP17A1)
   04917 Prolactin signaling pathway
    100400572 (CYP17A1)
   04927 Cortisol synthesis and secretion
    100400572 (CYP17A1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100400572 (CYP17A1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:cjc00199]
    100400572 (CYP17A1)
Enzymes [BR:cjc01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.19  steroid 17alpha-monooxygenase
     100400572 (CYP17A1)
    1.14.14.32  17alpha-hydroxyprogesterone deacetylase
     100400572 (CYP17A1)
Cytochrome P450 [BR:cjc00199]
 Cytochrome P450, animal type
  CYP17 family
   100400572 (CYP17A1)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 100400572
NCBI-ProteinID: NP_001254697
Ensembl: ENSCJAG00000018089
UniProt: Q5IFI0
LinkDB
Position
12:complement(92479196..92487678)
AA seq 507 aa
MWELVALLLFTLTYFFWPKRRSPGAKYPKSLLSLPLVGSLPFLPRHGHMHQNLFKLQKKY
GPIYSLRMGRNKTVIVGNHQLAKEVLMKKGKDFSGRPQVATIDILSNKGKGIAFADYGAH
WQLHRRLVMAAFSLFKEGDQKLEKIICQEISILCDVLATHDGQSIDISFPVFMAVTNVIS
LICFNSSYKDGAPELKIVETYNEGIVEALGKENLVDMFPWLKIFPNKSLEKLKTYVKLRN
DLLNKIIGNYKEKFHSDSITSMLDVLMQAKKNADNGNASPDQDAELLSDNHILTTVGDIF
GAGVETTTSVVKWIVAYLLHNPQVKKKLYDEIDQNVGFSRTPTVSDRNCLLLLEATIREV
LRIRPVAPMLIPHKANVDTSIGEFAVDKGTHVIINLWALHHSEEWHQPDKFMPERFLNQA
GTQLISPTLSYLPFGAGPRSCIGEILARQELFLIMAWMLQRFDLEVPDDGELPSLEGNPK
VVFMIDSFKVKIKVRQAWREAQAEGST
NT seq 1524 nt   +upstreamnt  +downstreamnt
atgtgggagcttgtggctctcttgctgtttaccctcacctatttcttttggcccaagaga
aggtcccctggtgccaagtaccccaagagcctcctgtccctgcccctggtgggcagcctg
ccattcctccccagacatggccatatgcatcagaacttattcaagctgcagaaaaaatat
ggacctatctattcccttcgtatgggcaggaacaaaacagtgattgtcggcaaccatcag
ctggccaaggaggtacttatgaagaagggcaaggacttctctggtcggcctcaagtggca
accatagacatcctgtccaacaagggcaagggcatcgccttcgctgactacggtgcacac
tggcagctgcatcgaaggcttgtgatggccgccttttccctgttcaaggagggtgatcag
aagctggagaagatcatttgtcaggaaatcagtatattgtgtgatgtgctggccacccac
gatggacagagcatagacatctcctttcctgtcttcatggcggtaaccaatgtcatctcc
ttgatctgcttcaattcctcctacaaggatggggcccctgagttgaagatcgtagagact
tacaacgaaggcattgtagaagccctgggcaaggagaacctggtagacatgttcccctgg
ttgaagattttccccaacaaatctctggaaaaattaaagacctatgttaaattacgaaat
gatctgctgaataaaataattggaaattacaaggagaaattccacagcgactctatcacc
agcatgctggacgtgctgatgcaagcgaagaagaacgcagataacggcaatgccagccca
gatcaagacgcagagctgctttcagataaccacattctcaccaccgtaggggacatcttt
ggggccggcgtggagaccaccacctctgtggtcaagtggatcgtggcctacctcctgcac
aatcctcaggtgaagaagaagctctacgatgagattgaccagaatgtaggtttcagccgc
acaccaactgtcagtgaccgtaactgtctgctcctgctggaggccaccatccgagaggtg
cttcgcatcaggcccgtggcccctatgctcatcccccacaaggccaacgttgacaccagc
atcggtgagtttgctgtggacaagggcacccatgttatcatcaatctgtgggcgctgcat
cacagtgaggagtggcaccagccagacaagttcatgcctgagcgtttcttgaatcaagcg
ggaacccagctcatctcaccgacattaagctacttgcccttcggagcaggacctcgctcc
tgtataggtgagatcctggcccgccaggagctcttcctcatcatggcctggatgctgcag
aggttcgacctggaggtgccagatgatggggaactgccctccctggaaggcaaccccaag
gtggtctttatgatcgactctttcaaagtgaagatcaaggtgcgccaggcctggagggaa
gcccaggctgagggtagcacctaa

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