| Entry |
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| Symbol |
LRP5
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| Name |
(RefSeq) low-density lipoprotein receptor-related protein 5 isoform X1
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| KO |
| K03068 | low density lipoprotein receptor-related protein 5/6 |
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| Organism |
cjc Callithrix jacchus (white-tufted-ear marmoset)
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| Pathway |
| cjc04928 | Parathyroid hormone synthesis, secretion and action |
| cjc05022 | Pathways of neurodegeneration - multiple diseases |
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| Brite |
KEGG Orthology (KO) [BR:cjc00001]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
100406268 (LRP5)
04150 mTOR signaling pathway
100406268 (LRP5)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
100406268 (LRP5)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100406268 (LRP5)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100406268 (LRP5)
05226 Gastric cancer
100406268 (LRP5)
05224 Breast cancer
100406268 (LRP5)
09164 Neurodegenerative disease
05010 Alzheimer disease
100406268 (LRP5)
05022 Pathways of neurodegeneration - multiple diseases
100406268 (LRP5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:cjc04131]
100406268 (LRP5)
Membrane trafficking [BR:cjc04131]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
100406268 (LRP5)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
11:121933034..122070484
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| AA seq |
1611 aa
MEAAPPRPPWPLLLLLVLGGCSAPAAASPLLLFANRRDVRLVDAGRVKLETTVVVSGLED
AAAVDFQFSKGVVYWTDVSEEAIKQTYLNHTGVAVQNVVISGLVSPDGLACDWVGKKLYW
TDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALNPAHGYMYWTDWGEMPRIERAGMDGT
TRNIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALT
LSGDTLYWTDWQTRSIHACNKRTGGKRKEILSALYSPMDIQVLSQERQPFFHTRCEEDNG
GCSHLCLLSPVEPFYKCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFTD
IVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLINTDINDPDGIAVD
WVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGENPKI
ECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDK
LPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDIIIDQLPDLMGLKAVNVAKIMGTNP
CADENGGCSHLCFFTPRSTRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISLETNN
NDVAIPLTGVKEASALDFDVANNHIYWTDVSLKTISRAFLNGSSVEHVVEFGLDYPEGMA
VDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTEGYIYWTEWGGKP
RIVRAFMDGTNCMTLVDKVGRANDLTIDYTDRRLYWTDLDTNMIESSNMLGQERVVIADD
LPHPFGLTQYSDYIYWTDWNLHSIERADKTSGQNRTLIQGHLDFVMDILVFHSSRQDGLN
DCVHDNGQCGQLCLAIPGGHRCGCASHYTLDPSGRNCSPPTTFLLFSQKSAISRMIPDDQ
HSPDLVLPLHGLRNVKAIDYDPLDKFIYWVDGRQNIKRAKDDGTQPFVLTSLSQAQNPDR
QPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAIGVVLRGDRDKPRAIVVNAERGYLYFT
NMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNALGKLFWADADLKRIESCDLSGA
NRLTLEDANIVQPLGLTVLGKHLYWIDRQQQMIERVEKTTGDKRTRIQGRVTHLTGIHAV
EDVSLEEFSAHPCARDNGGCSHICIAKGDGTPRCSCPVHLVLLQNLLTCGEPPTCSPDQF
ACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRLRCDGEADCQ
DRSDEADCDAICLPNQFRCASGQCVLIKQQCDSFPDCIDGSDELMCEINKPPSDDTGAHS
SAIGPVIGIILSLFVMGGIYFVCQRVVCQRYAGANGPFPHEYVSGTPHVPLNFIAPGGSQ
HGPFTGIACGKSMMSSVSLMGGRGGVPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSP
ATDPSLYNMDMFYSSNIPATTRPYRPYIIRGMAPPTTPCSTDVCDSDYSASRWKASKYYL
DLNSDSDPYPPPPTPHSQYLSAEDSCPPSPATERSYFHLFPPPPSPCTDSS |
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| NT seq |
4836 nt +upstreamnt +downstreamnt
atggaggcagcgccgccccggccgccgtggccgttgctgctgctgctggtgctgggtggc
tgctcggcccccgccgcggcctcgccactcctgctgtttgcaaaccgccgggatgtacgg
ctggtggacgccggcagagtcaagctggagaccaccgtcgtggttagcggcctggaggat
gcggccgctgtggacttccagttctccaagggagtcgtgtactggacagacgtgagtgag
gaggccatcaagcagacctacctgaaccacacgggcgtcgccgtccagaacgtggtcatc
tctggcctggtctcgcccgacggcctggcctgcgactgggtgggcaagaagctgtactgg
acggactcagagaccaaccgcatcgaggtggccaacctcaatggcacgtctcggaaggtc
ctcttctggcaggaccttgaccagccgagggccatcgccttgaaccccgctcacgggtac
atgtactggacagattggggtgagatgccccggatcgagcgggcggggatggacggcacc
acccggaatatcattgtggactcggacatttactggcccaatgggctgaccatcgacctg
gaggagcagaagctctactgggctgacgccaagctcagcttcatccaccgcgccaacctg
gatggctcgttccggcagaaggtggtggagggcagcctgacgcaccccttcgccctgacg
ctctcgggggacactctgtactggacagactggcagacccgctccatccatgcctgcaac
aagcgcactgggggtaagaggaaggagatcctgagcgccctctactcacccatggacatc
caggtgctgagccaggagcggcagcctttcttccacactcgctgcgaggaggacaatggt
ggctgctcccacctgtgcctgctgtccccggtggagcctttctacaagtgtgcctgcccc
acgggcgtgcagctgcaggacaatggcaggacgtgtaaggcaggagccgaggaggtgctg
ctgctggcccggcggacagacctgcggaggatctcactggacacgccggacttcaccgac
atcgtgctgcaggtggatgacatccggcacgccattgccatcgactatgacccgctggag
ggctacgtctactggacggatgacgaggtgcgggccatccgcagggcgtacctggatggg
tcgggggcgcagacgctgatcaacaccgacatcaacgaccccgacggcatcgcagtcgac
tgggtggcccgaaacctctactggaccgacacgggcactgaccgcatcgaggtgacacgc
ctcaacggcacctcccgcaagatcctggtgtcggaggacctggacgagccccgcgccatc
gcgctgcaccccgtgatgggcctcatgtactggacagactggggagagaaccctaaaatc
gagtgtgccaacctggacgggcaggagcggcgtgtgctggtcaatgcctcccttgggtgg
cccaacggcctggccctggacctgcaggaggggaagctctactggggagacgccaagacg
gacaagatcgaggtgatcaatgtcgatgggacgaagaggcggaccctgctggaggacaag
ctcccgcacatttttgggttcacgctgctgggagacttcatctactggactgactggcag
cgccgcagcattgagcgggtgcacaaggtcaaggccagccgggacattatcattgaccag
ctgcccgacctgatggggctcaaagccgtgaatgtggccaagatcatgggaaccaacccg
tgcgctgatgagaacggcgggtgcagtcacctgtgcttcttcacgccccgctccacccgg
tgtggctgccccatcggcctggagctgctgagcgacatgaagacctgcatcgtgcccgag
gccttcttggtcttcaccagcagagccgccatccacaggatctccctcgagaccaacaac
aacgacgtggccatcccgctcacgggcgtcaaggaggcctcagccctggactttgacgtg
gccaacaaccacatctactggacggacgtcagcctgaagaccatcagccgtgccttcctg
aacgggagctccgtggagcacgtggtagagtttggccttgactaccccgagggcatggcc
gttgactggatgggcaagaacctctattgggctgacaccgggaccaacaggatcgaagtg
gcgcggctggacgggcagttccggcaagtcctcgtgtggagggacctggacaacccgagg
tcactggccctggatcccaccgagggctacatctactggactgagtggggcggcaagccg
aggattgtgcgggccttcatggacgggaccaactgcatgacgttggtggacaaggtgggc
cgggccaacgacctcaccattgactacactgaccgtcgcctctactggaccgacctggac
accaacatgattgagtcgtccaacatgctgggtcaggagcgggtcgtgattgccgacgac
ctgccgcacccgttcggtctgacgcagtacagcgattatatctactggacggactggaat
ctgcacagcatcgagcgggccgacaagaccagcggccagaaccgcaccctcatccagggc
cacctggacttcgtgatggacatcctggtgttccactcctcccgccaggatggcctcaac
gactgcgtgcacgacaacgggcagtgcgggcagctgtgccttgccatccccggcggccac
cgctgcggctgcgcctcacactacaccctggaccccagcggccgcaactgcagcccaccc
accaccttcttgctgttcagccagaaatctgccatcagccggatgatcccggacgaccag
cacagcccggacctcgtcctgcccctgcacgggctgaggaacgtcaaggccatcgactat
gacccactggacaagttcatctactgggtggacgggcgccagaacatcaagcgagccaag
gacgacgggacccagccctttgttttgacctctctgagccaagcccaaaacccagacagg
cagccccacgacctcagcatcgacatctacagccggacgctgttctggacatgtgaggcc
accaacaccatcaacgtccacaggctgagcggggaagccattggggtggtgctgcgtgga
gaccgcgacaagcccagggccatcgtcgtcaacgcagagcgagggtacctgtacttcacc
aacatgcaggaccgggcagccaagatcgagcgtgcggccctggacggcactgagcgggag
gtcctcttcaccaccggtctcatccgccccgtggccctggtggtagacaatgcactgggc
aagctgttctgggcggatgcagacctgaagcgcattgagagctgcgatctctcaggggcc
aaccgcctgaccctggaggacgccaacatcgtgcagcctctgggcctgactgtgcttggc
aagcacctctactggatcgaccgccagcagcagatgattgagcgtgtggagaagaccacc
ggggacaagcggactcgcatccagggccgcgtcacccacctcacgggcatccacgcggtg
gaggacgtcagcctggaggagttctcagcccacccatgtgcccgtgacaatggtggctgc
tcccacatctgtattgccaagggtgatgggacaccacggtgctcatgcccagtccacctc
gttctcctgcagaacctgctgacctgtggagagccgcccacctgctcccctgaccagttt
gcgtgtgccaccggggagatcgactgtatccccggggcctggcgctgcgacggctttcct
gagtgtgacgaccagagtgacgaggagggctgccccgtgtgctccgctgcccagttcccc
tgcgcccggggccagtgtgtggacctgcgcctgcgctgcgatggcgaggctgactgtcag
gatcgctcagacgaggccgactgtgacgccatctgcctgcccaaccagttccggtgtgcc
agcggccagtgcgtcctcatcaagcagcagtgtgactccttccccgactgcattgacggc
tccgatgagctcatgtgtgaaatcaacaagccgccctcagatgacactggagcccacagc
agcgccatcgggcctgtcatcggcatcatcctctccctctttgtcatgggtggcatctac
tttgtgtgccagcgcgtggtgtgccagcgctatgcgggggccaatgggcccttcccgcac
gagtatgtcagcggcacaccgcacgtgcctctcaatttcatagccccgggtggttcccag
catggtccctttacaggcatcgcatgtggaaagtccatgatgagctctgtgagcctgatg
gggggccggggcggggtgcccctctacgaccggaaccacgtcacaggggcctcatccagc
agctcatccagcacgaaggccacgctgtacccgccgatcctgaacccaccaccctccccg
gccacggacccctcgctgtacaacatggacatgttctactcttcaaacattccggccacc
acgagaccgtacaggccttacatcattcgaggaatggcacccccgacgacaccctgcagc
accgacgtgtgtgacagcgactacagtgccagccgctggaaggccagcaagtactacctg
gatttgaactcagactcagacccctacccgcccccacccacgccccacagccagtacctg
tcggcagaggacagctgcccgccctcgcccgccacagagaggagctacttccacctcttc
ccgccccctccatccccctgcacggactcgtcctga |
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