Corynebacterium jeikeium: jk0746
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Entry
jk0746 CDS
T00255
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cjk
Corynebacterium jeikeium
Pathway
cjk00300
Lysine biosynthesis
cjk00550
Peptidoglycan biosynthesis
cjk01100
Metabolic pathways
cjk01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cjk00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
jk0746 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
jk0746 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
jk0746 (murF)
Enzymes [BR:
cjk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
jk0746 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Myb_DNA-binding_2
Motif
Other DBs
NCBI-ProteinID:
CAI36908
UniProt:
Q4JW99
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Position
890768..892282
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AA seq
504 aa
AA seq
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MIELTTQKIAEVSGSTLINDVDPQAVVTGPVEFDSRKITPGAIFMALPGARADGHDFADA
ALNSGAALLIVGRPVEQPALLAAPVEINEQTSNATAFEFDAEGHGAAVLAAIDKLARYNT
DVLAAEEGMVVVGVTGSAGKTSTKDLIGAVLREAGETVAPPGSFNNEIGLPYTALRAGRD
TRFLVSEMSARGVGHIQHLTTVTPPRVGVVLNVGSAHLGEFGSRQAIAQAKGELVEALPA
AADGGLAVLNADDDKVAAMDKRTAARVVRFSTEGATGAAGVPADYYATDIELDAVARASF
MLHHPVGEPVRVELSVFGAHQVSNALAAAAVGIEMGIDAATVASLLSSHVAASVNRMDVR
TRESDGVTIINDSYNANPESMRAGIDALAYTAKGRRDAASWAVLGQMGELGEDASDEHAE
LGHVLAQRRIDHAVIVGNGVNQRALANAARESGVETQVVENIDGAVNYLDMSLNPQDVVL
IKASYSDGLWAVAEGLLIGEDQGA
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgattgagttaacgacacagaagatcgccgaggtatccggcagcacgctgattaacgac
gtggatccgcaggccgtagtgaccggcccggtggagttcgactcgcgcaagatcacaccg
ggcgcgatcttcatggctctgccaggtgcacgtgccgacggccacgacttcgccgatgca
gctctgaacagcggcgccgcgctgctgatcgttggccgcccggtggagcagcccgccctg
ctggccgccccggtggagatcaacgaacaaacctccaatgccaccgcattcgagttcgac
gcggaaggtcacggcgcagcagtgctggcagcgatcgataagctcgcgcgctataacacc
gacgtgctcgctgccgaggagggcatggtcgtcgtcggcgtgaccggctctgcgggcaag
acctccacgaaggatctgattggcgcggtgctgcgcgaggcaggggagaccgtcgctccg
cccggcagtttcaacaacgagatcggcctgccttacacagccctgcgtgcgggccgcgac
acgcgcttcctcgttagcgagatgtccgcccgtggcgtaggccacatccagcacttgacg
accgttaccccgccgcgagtgggtgtggtgctgaacgtcggcagtgcccacctgggcgag
ttcggctcccgccaggccatcgcgcaggcgaagggcgagctggtggaggctctgccggct
gccgctgatgggggcctggccgtgctgaacgcagacgacgacaaggttgcggcgatggat
aagcgcaccgccgcgcgcgtcgtgcgtttttccacggaaggcgcgacgggggcagcgggc
gtgccggcggattactatgcgaccgacatcgagctcgacgctgtagcccgcgccagcttt
atgctgcaccacccagtaggggagccggtgcgtgtggaactttcggtattcggcgcccac
caggtctcgaacgcgctcgccgccgcggcggttggtatcgagatgggtattgacgccgcc
acggtcgcatccctgctgagctctcacgttgccgctagcgtaaaccgcatggatgtgcgc
acccgcgaatctgacggagtgaccatcatcaacgattcttataacgccaaccccgaatcc
atgcgcgcgggaatcgacgcgctggcttacaccgccaagggccgtcgcgatgcggcgagc
tgggccgtgctggggcagatgggtgagttgggcgaggacgctagcgacgagcacgccgag
ctcggccacgtgctggcgcaacgacgcatcgaccacgcggtgatcgtgggcaacggggtg
aatcagcgtgcgctggccaacgctgctcgagagagcggtgtggaaacccaagtcgtcgaa
aacatcgacggcgcggtgaattacctagatatgagtttgaatccgcaggatgtagtgctg
atcaaggcatcgtattcggacggactatgggcagtggctgaaggactgctcatcggtgag
gatcaaggagcttaa
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