Corynebacterium jeikeium: jk1313
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Entry
jk1313 CDS
T00255
Symbol
ilvA
Name
(GenBank) Threonine dehydratase (EC 4.3.1.19),Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine followed by rehydration and liberation of ammonia.
KO
K01754
threonine dehydratase [EC:
4.3.1.19
]
Organism
cjk
Corynebacterium jeikeium
Pathway
cjk00260
Glycine, serine and threonine metabolism
cjk00290
Valine, leucine and isoleucine biosynthesis
cjk01100
Metabolic pathways
cjk01110
Biosynthesis of secondary metabolites
cjk01200
Carbon metabolism
cjk01230
Biosynthesis of amino acids
Module
cjk_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
cjk00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
jk1313 (ilvA)
00290 Valine, leucine and isoleucine biosynthesis
jk1313 (ilvA)
Enzymes [BR:
cjk01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.1 Ammonia-lyases
4.3.1.19 threonine ammonia-lyase
jk1313 (ilvA)
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Motif
Pfam:
PALP
Thr_dehydrat_C
Malt_amylase_C
DUF7529
Motif
Other DBs
NCBI-ProteinID:
CAI37485
UniProt:
Q4JUM2
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Position
complement(1553248..1554801)
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AA seq
517 aa
AA seq
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MADAPGTETISGAEYLKRIVSAPVYRVATNTPLEHMETLSNRIGNEVLVKREDLQPVHSF
KIRGAFNRMSQLTDEERARGVVAASAGNHAQGVALSGTELGIRTVIVMPEVTPSIKIDAV
RSFGGEVLLHGANFDEAKAKAMELSEVEGMVWVAPFDDEAVIAGQGTAGLEIFQSRPDVD
RVFVQVGGGGLAAGISVLLKELDPNIQVIGVEPEESACLTHALAAGHPVALDHVSLFAEG
VAVKQIGNETFRVCREYLDDVITVSSDEISAAIKDIFDDTRAIAEPAGAVALAGLKRYAA
DHQVEGETLAHVLSGANVNFHSLRYVSERAEIGEGGEGIFGVSIPEREGAFLEFCKILGH
RAVTEFSYRVGQRDGEKPARIFVGVKLKNGEDERKAIAEDLREAGYGVVDLSDDDVAKEH
VRYMIGGNPGQHVDETAYSFEFPENPGALLHFLEVLGTRWNITGFHYRSFGMDHGRVLAA
FEDVSGDVEFQEHLEQLGYHATDVTDSPAYDFFISAE
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atggcagatgcccctggcacggagaccatttccggtgcggagtatctgaaaaggattgtc
tccgcacctgtctaccgagtggccacgaacacgccgctcgagcacatggaaacgctgtcg
aatcgtatcggcaacgaggtgctggtcaagcgcgaagacctgcagcctgtgcacagcttc
aagattcgcggcgcattcaaccgcatgtcccagctcacagacgaagaacgcgcccgcgga
gtcgtcgccgcctccgccggcaaccacgcccaaggcgtagcgctttccggcacggagctt
ggtatccgcaccgttatcgtgatgccggaagtgacccccagcatcaagatcgacgccgtc
cgcagcttcggcggggaagtgctgctgcacggcgcgaacttcgacgaagccaaggccaag
gctatggagctctccgaagttgagggcatggtgtgggtcgcacccttcgacgacgaagcc
gtcatcgccggccagggcaccgccgggttggagatcttccaatcccgccccgacgtcgac
cgcgtcttcgtacaggtcggtggcggcggactggccgccggaatctccgtgcttctcaaa
gaactagaccccaacatccaggtcatcggagtggagcccgaagaatccgcctgcctcacc
cacgcgctagccgccgggcaccccgtggccctcgaccacgtaagcctcttcgccgaaggc
gtggccgtcaagcagatcggcaacgaaaccttccgagtctgccgcgaatacctcgacgac
gtcatcaccgtcagctcggatgagatcagtgccgccatcaaggatatcttcgacgacact
cgcgccatcgccgagccagccggcgccgtcgccctggcaggcctgaagcgctacgccgcc
gaccaccaagtcgaaggggagaccctggcgcacgtcctgtccggcgcgaacgtgaacttc
cactccctgcgctacgtctccgaacgcgcggaaatcggcgagggcggcgaaggcatcttc
ggcgtgagcatccccgagcgcgagggagccttcctcgaattctgcaagatcctcggccac
cgcgccgtcacagaattcagctaccgggtaggccagcgcgacggggaaaagcccgcccgc
attttcgtgggcgtcaagctcaaaaacggtgaggacgagcgcaaggccatcgccgaagac
ctccgcgaggcaggctacggcgtggtggacctgtccgacgacgacgtagccaaggaacac
gtccggtacatgatcggcggcaaccccggccagcacgtcgacgaaaccgcctacagtttc
gagttccccgaaaacccgggagccctactgcacttcttggaagtcctgggaacccgctgg
aacatcaccggtttccactaccgcagcttcggcatggaccacggccgcgtgctggcggcg
ttcgaggacgtctccggcgacgtggaattccaggagcacctggagcagctcggctaccac
gccacggacgtgacagacagcccggcctacgacttcttcatcagcgccgaataa
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