Corynebacterium jeikeium: jk1900
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Entry
jk1900 CDS
T00255
Symbol
hemD
Name
(GenBank) uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cjk
Corynebacterium jeikeium
Pathway
cjk00860
Porphyrin metabolism
cjk01100
Metabolic pathways
cjk01110
Biosynthesis of secondary metabolites
cjk01120
Microbial metabolism in diverse environments
cjk01240
Biosynthesis of cofactors
Module
cjk_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
cjk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
jk1900 (hemD)
Enzymes [BR:
cjk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
jk1900 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
jk1900 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
CAI38081
UniProt:
Q4JSX6
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All DBs
Position
complement(2214090..2215976)
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AA seq
628 aa
AA seq
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MTDSGNAQVGGADSAAVAAVADLAPTGCGRILFVGAGPGNPELLTIRARDILETTAHAWV
DPSVLESVQKIIATRLPVPQEKLDAAEAEWEAKVKAAKDAGARRRPPRPTPPTAAEIVLA
APAATDPELAAELGPEAGGETGAEAGAETGKETYGEPVPEAVAPEVLAEQMVACAMAGND
VVRLVAGNPLSNPAVMNELQHVAASSVEFQVIPGMTGSVAVPAFTGIGLGPDVTEADVRG
GADWDQLAAAGLPLILTAAPDNLATIAQELKARGISGATPATVTLHGTTRRQRSYDATLD
TLKSITTQSGPAAKDGELPAELIVTLGSQVGNRSKYSWWENRALYGWTVLVPRAKNQAGP
MSTRLASHGAIPVEVPTISVEPPRSPVQMERAIKGLVDGRYHWIVFTSVNAVKAVWEKLR
EFGLDARALAGVRVAAVGPKTSQAVKDLGITPELLPKDDARNAAGLVEVFPPHDPDLDLV
DRVLLPRADIATDVLVDGLIELGWDVEDVVAYRTVRAAPPSPEIRDMIKTGGFDAVCFTS
SSTVKNLVGIAGKPHARTIIACIGPMAAQTAREHGLRVDVMPEAAGVPELVDALADHVAD
LRAKGQLPPPRKRRRRRKKSNEKKDTGA
NT seq
1887 nt
NT seq
+upstream
nt +downstream
nt
atgaccgattccggaaatgcccaggtaggaggcgcggattccgccgcagtggcggcagtc
gccgacctggcacccactggatgcggccggatcctcttcgtgggcgcgggccccggaaac
ccggagctgctgaccatccgcgcgcgcgacattctggagaccaccgctcatgcgtgggtg
gatccgtcggtattggaatccgtgcagaaaatcatcgccacccgcttgccggtgccgcag
gagaagctggatgcagccgaagcggagtgggaagcgaaggtgaaggctgctaaggatgcc
ggtgcgcgccgccgtcccccgcgtccgaccccgccgacggcggcggagatcgtgctggcc
gccccggcagctacagacccagaacttgccgctgagcttggccctgaggccggtggagag
actggcgctgaagcgggcgcagagacgggcaaggagacctacggcgagccggtgccggaa
gccgtcgcaccggaagttctggccgagcaaatggtcgcctgtgccatggcgggcaacgac
gtggtgcgacttgtcgccggcaacccgctaagtaacccggcggttatgaatgagctacag
catgtagcagcaagctcggtggaattccaggtcatccctggcatgaccggatccgtggcc
gttcccgccttcaccgggatcggcctcggcccggacgtcaccgaggccgatgttcgcggt
ggtgctgactgggatcagctggccgctgccggacttccgctgattctcaccgctgccccg
gacaacctggcaaccatcgcacaggagctgaaggcccgcggcatctccggagccaccccg
gcgaccgttacactgcacggcaccacccgtcgccagcgcagctacgatgcgaccctggac
acgctgaagtccatcactacccagtctggccccgccgccaaggatggcgagctgccagcc
gagctgatcgtcactctgggttctcaggtgggcaaccgctccaagtactcctggtgggag
aaccgcgccctgtacggctggacggtgttggtgccgcgtgccaagaaccaggccggcccc
atgagcacccgcctggcttctcacggtgctatccccgtggaggtgcccactatctccgtg
gagccaccccgcagccccgtgcaaatggagcgcgctatcaaggggctcgtcgatggccgc
taccactggatcgtattcaccagtgtcaacgctgtgaaggccgtgtgggagaagctacgc
gagttcgggctcgacgctcgtgccttggcaggcgtgcgcgtggccgccgtggggccgaag
acctcccaggcggtgaaggacctgggaatcaccccggaactgctgccgaaggacgacgca
cgcaatgccgcgggtctggtggaggtcttcccgccacacgacccggacctggatctggtt
gaccgcgtgctgctgccgcgcgccgacatcgccaccgacgtgctggtcgacggcctgatc
gaactcggctgggacgtggaggacgtcgtggcctaccgcaccgtccgcgccgccccgccc
agcccggagatccgcgacatgatcaagaccggtggcttcgacgcagtctgcttcaccagc
tcctcgaccgtgaagaacctggtgggcatcgcgggcaagccacacgcgcgcaccatcatc
gcctgcatcgggccgatggctgcacagaccgctcgcgagcatggcctgcgcgtcgacgtc
atgcccgaggccgctggcgtgccggagcttgtggacgccctcgctgaccacgtggctgac
ctgcgcgctaagggacagcttccgcctccgcggaagcggaggcggcgtcgtaaaaagtcg
aacgagaagaaggacaccggggcctaa
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