Caldicellulosiruptor acetigenus I77R1B: Calkr_0483
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Entry
Calkr_0483 CDS
T01356
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
cki
Caldicellulosiruptor acetigenus I77R1B
Pathway
cki00290
Valine, leucine and isoleucine biosynthesis
cki00660
C5-Branched dibasic acid metabolism
cki01100
Metabolic pathways
cki01110
Biosynthesis of secondary metabolites
cki01210
2-Oxocarboxylic acid metabolism
cki01230
Biosynthesis of amino acids
Module
cki_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cki00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Calkr_0483
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Calkr_0483
Enzymes [BR:
cki01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Calkr_0483
4.2.1.35 (R)-2-methylmalate dehydratase
Calkr_0483
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
ADQ40032
UniProt:
E4S9H8
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Position
526509..527801
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AA seq
430 aa
AA seq
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MAKPMTMSQKILAYHAGKEYVEPGDLIFANVDLVLGNDVTTPVAIKEFEKIGIDRVFDKD
KIAIVPDHFTPNKDIKSAQQCKMVREFTKKYEITNYFEVGEMGIEHALLPEKGLVVPGDL
VIGADSHTCTYGALGSFSTGIGSTDMACAMATGKCWFKVPEAIKFVLYGKKTGWTSGKDI
ILHIIGMIGVDGALYKSMEYTGEGLKSLSMDDRFTIANMAIEAGAKNGIFEVDEKTIEYV
KQHSTKPYKIFKADEDAEYSQVFEIDISKIRPTVAFPHLPENTKTIDEITEKIYIDQVVI
GSCTNGRIEDLRIAAKILKGRKVKKGLRCIIFPATQNIYKQALKEGLIEIFIDAGCVVST
PTCGPCLGGHMGILADGEKALATTNRNFVGRMGHPNSEVYLSSPAIAAASAVLGYIGSPE
ELGMKGDEEQ
NT seq
1293 nt
NT seq
+upstream
nt +downstream
nt
atggcaaaaccgatgacaatgtcccagaagattttggcgtatcatgcaggaaaagaatat
gttgagccaggtgatttgatttttgcaaatgttgaccttgttttggggaatgacgttaca
acacctgttgcaataaaggagtttgaaaagatagggattgacagggtttttgacaaagat
aaaattgcaatagttcccgaccattttactccaaacaaagacataaagtctgctcagcag
tgcaagatggttcgagagtttactaaaaagtatgagattacaaattactttgaagttggc
gagatgggcattgaacatgcactcttgccagagaaaggacttgttgtgccgggtgatttg
gtaattggtgcagactctcatacatgcacatatggagctcttggcagcttctcaacagga
attggttcgactgacatggcatgtgcaatggcaacaggcaagtgctggtttaaagtacca
gaggccatcaagtttgtcctctacggcaagaaaactggctggacatcaggcaaagatatc
atccttcacattatcggtatgataggtgttgatggtgcactttacaagtcaatggaatac
acgggtgaaggtttaaaatcactttcgatggatgacaggtttactatcgctaacatggca
attgaagcgggtgcgaaaaatggcatatttgaggttgatgaaaagacaattgagtatgta
aaacagcactctacaaaaccttataagatattcaaggcagacgaggatgcagagtattca
caggtctttgagattgatatttcaaaaattagacccacagttgcgtttccacaccttcca
gagaacacaaaaacaatagatgagataacagaaaagatttatattgaccaagttgtgatt
ggctcatgcacgaacggcagaattgaagacttgaggattgcagcaaagatcttaaaagga
agaaaggttaaaaaaggactcagatgtatcatatttcctgcaacacagaatatatacaag
caggcattaaaagagggactcattgagatatttattgacgctggatgtgttgtttcaaca
cccacttgcggcccatgtcttggcgggcacatgggaattttggcagatggtgagaaggct
cttgctacaacaaatagaaactttgttggcaggatgggtcatccaaatagtgaggtttat
ctgtcatcacctgcaattgcagcagcatcagcagttttaggctacattggctcacctgaa
gagcttggtatgaagggagatgaagagcaatga
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