Caldicellulosiruptor acetigenus I77R1B: Calkr_1817
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Entry
Calkr_1817 CDS
T01356
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
cki
Caldicellulosiruptor acetigenus I77R1B
Pathway
cki00290
Valine, leucine and isoleucine biosynthesis
cki00620
Pyruvate metabolism
cki01100
Metabolic pathways
cki01110
Biosynthesis of secondary metabolites
cki01210
2-Oxocarboxylic acid metabolism
cki01230
Biosynthesis of amino acids
Module
cki_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cki00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Calkr_1817
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Calkr_1817
Enzymes [BR:
cki01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Calkr_1817
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Ecm33
Motif
Other DBs
NCBI-ProteinID:
ADQ41303
UniProt:
E4S436
LinkDB
All DBs
Position
complement(1867284..1868864)
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AA seq
526 aa
AA seq
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MENNKTIIIYDSTLRDGAQAGGISYTLEDKLKIVERLDKFGVKFIEAGNPGSNIKDQEFF
ARVKKMRLKNAKLIAFGSTRRVGIDVKDDPNIQSLIAADTEAVAIFGKSWDFHVKEVLKT
TEDENLQMIYDTIKYLKSLGKYVVFDAEHFFDGYKNNKKYALETLKVAKEAGADSLDLCD
TNGGTFPMDIYNITKEVVEMFPGTLIGIHCHNDTGMAVANSIMAVLAGARQVQGTINGYG
ERCGNADLITLIPNLQLKLGFKCVPDENIKHLTSLSRYVAEIANMIPNERAPYVGAYAFT
HKAGMHIDAVKKNPASFEHINPEVVGNTRRIVLSEVAGRATILDKIREIDPTVTKDSPVT
KEIIDELKRLENEGYQFESAEASFEMLIRKKLGLYQPFFTLKEFKVLINEPAVEYSSSAI
VKIAVDGVTAITAAEGDGPVHALDNALRKALEKFYPELKEVHLVDYKVRVLNAETATAAK
VRVLIESTDGKDTWTTVGVSTDIVNASWIALVDSLEYKLCKEKVGK
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
gtggaaaataataagaccattatcatctatgactcaaccttaagagacggtgctcaggct
ggtggaatttcatatactctggaagataagctcaagattgtagagaggcttgacaaattt
ggtgtgaaatttatcgaggcaggcaatcccggttctaacatcaaagaccaggaatttttc
gcaagagttaaaaagatgagattgaaaaacgcaaagcttatcgcctttggttcaacaagg
cgagtgggaattgacgttaaagatgaccctaacatccagtcgctaattgctgctgacacc
gaagctgttgcaatctttggcaagtcgtgggattttcatgtcaaagaggtcttgaaaaca
acagaggacgaaaatcttcagatgatttatgacactataaaatatttaaagtctttgggc
aagtatgttgtatttgacgcagagcacttttttgatggctacaagaataacaaaaaatac
gctttggagactttaaaggttgcaaaagaggcaggtgcagattctttagacctgtgcgat
acaaacggtggcaccttcccaatggatatttataacatcacaaaagaagttgttgagatg
tttcctgggacattaattggaattcactgtcacaacgacacaggtatggctgttgcaaac
tcaatcatggcagttttggcaggagcacgtcaggttcagggaactataaacggatatggt
gagaggtgtggaaatgcagaccttatcacgctcataccaaatcttcagctaaagcttggc
tttaaatgtgtaccagatgagaacataaaacacctgacatcactttcaaggtatgttgca
gagattgccaacatgattccaaacgaaagagcaccatatgttggagcttatgcatttact
cacaaggccggaatgcacattgatgctgtcaagaaaaatccagcctcttttgagcatatc
aatcctgaggttgttggaaatacaagaaggatagtactgtctgaggttgcaggaagggct
acaattcttgacaagattcgcgagattgacccgacagttacaaaagactcacctgtgaca
aaagagattattgatgagctaaagcgccttgaaaatgaagggtatcagtttgagtctgca
gaggcttcatttgagatgttaattagaaaaaagctgggactttatcagccgttctttact
ctcaaagagtttaaagtgctcattaacgagccggcagtagagtacagctcatctgcaatt
gtaaagattgcggtagatggggttacagcaatcactgctgcagaaggtgatggccctgtt
catgctttagataatgctttgagaaaggctttggaaaaattctacccagagctaaaagag
gtgcatcttgttgactataaagtgcgggtactgaatgcagagactgcaactgctgcaaag
gtaagagttctgattgagtcaacagacggcaaagacacctggacaactgtaggtgtttca
accgacattgtaaatgcaagctggattgcacttgttgactcactggagtataagctttgc
aaagaaaaagtggggaaataa
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