Clostridium sp. BNL1100: Clo1100_4048
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Entry
Clo1100_4048 CDS
T01708
Name
(GenBank) 2-isopropylmalate synthase, bacterial type
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
clb
Clostridium sp. BNL1100
Pathway
clb00290
Valine, leucine and isoleucine biosynthesis
clb00620
Pyruvate metabolism
clb01100
Metabolic pathways
clb01110
Biosynthesis of secondary metabolites
clb01210
2-Oxocarboxylic acid metabolism
clb01230
Biosynthesis of amino acids
Module
clb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
clb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Clo1100_4048
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Clo1100_4048
Enzymes [BR:
clb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Clo1100_4048
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
DUF3231
Motif
Other DBs
NCBI-ProteinID:
AEY68149
UniProt:
H2JB62
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All DBs
Position
complement(4535962..4537488)
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AA seq
508 aa
AA seq
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MARTIKIFDTTLRDGEQTPGVNLNLQEKMEIAKQLVRLGVDVIEGGFAIASPGDFESIMT
LSRNLKGVTIASLCRAVEKDIDRAWEAVQYAESPRIHTFIATSDIHMKYKLKMTEEEVLE
RAVAMVKHAKAYCSNVEFSAEDASRTREEFLYRIVEAVINAGATTVNIPDTVGYSTPQEF
GRLIRNIRNNVPNIDKADISVHCHNDLGLAVANSLAAVANGAVQVECTINGLGERAGNAA
IEEIIMGINTRKDYYDITHKIDTTQIYRASRLVSSLTGVNVQPNKAIVGANAFAHESGIH
QHGVLSEKTTYEIMTPESVGMGQNRMVLGKLSGHHAFEERLREMGYSLSDEEVKTAFTKF
KDLADKKKVVTDKDIEALVDENIAVPEIFVIDSFQINSGNKMISTSTVSIKKDEDIITEA
ATGDGPVDAAFNAIERATGVNAELVHYSIKAVTEGKDALGEVTVKISNNNSVFMGKGVST
DIIEASVKAYLNAINRSISEIGESIINQ
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atggccagaacgattaagatatttgataccacattaagggatggagagcaaacacccggt
gttaaccttaatctccaggaaaagatggaaatagcaaagcaactggtaaggctaggtgta
gacgttattgagggcggatttgccattgcatcccccggcgactttgaatcaataatgaca
ctttccaggaacctgaaaggggttacaatagcaagcctgtgccgtgccgtagaaaaagat
atagatagagcttgggaggcagttcagtatgcggaaagcccaagaatacacacctttatt
gctacttcggatatccatatgaaatacaagttgaaaatgacagaagaagaggtgctggaa
agggctgtagccatggtcaaacatgccaaagcctactgttccaatgttgaattttcagca
gaagatgccagcagaacccgggaggagttcctgtatcgtatagtagaagctgttatcaat
gccggagctacaacagtaaatattccggatacggtgggatattcaactccgcaggagttt
ggaagacttataaggaatataagaaataatgtacctaatattgacaaggcggatataagc
gttcactgtcataacgatttgggccttgctgttgctaattcacttgcagctgttgcaaat
ggagctgtacaggttgaatgtacaattaacggtcttggtgaaagagccggaaatgctgcg
atagaagaaataataatgggtataaatacaagaaaagattactatgatataacacataag
attgatacaacacagatataccgggcaagcaggcttgtctcaagccttaccggtgtgaat
gtacaacccaataaggcaatcgtgggagcaaatgcttttgcacacgagtcaggaatacat
caacatggtgtactttctgaaaagaccacttatgagattatgactcccgaatcagtagga
atgggtcagaacagaatggttctgggcaagctgtcaggacatcacgcttttgaagaaaga
ttgagagagatgggttactccctgtctgatgaagaagtaaagactgcctttacaaaattt
aaagatttggctgacaagaaaaaggtagtcactgacaaggatattgaagcactggtagat
gaaaacattgcggttcctgaaatcttcgtaatagatagttttcagataaacagcggaaat
aaaatgatatcaacctcaacggtcagtattaaaaaagatgaggacatcataaccgaagct
gcaacgggagatggccctgtagatgcagcatttaacgcaattgagcgtgctacgggggtt
aatgcagagttggttcattatagtataaaggcggtaacggaaggaaaggatgctcttggt
gaggtaaccgtaaaaatatcgaacaataacagcgtatttatgggcaagggtgtcagtact
gacatcattgaggccagtgttaaggcatacctgaatgcaataaacaggtctataagcgaa
attggagaaagcataattaaccagtaa
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