Caldicellulosiruptor acetigenus 6A: Calla_1214
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Entry
Calla_1214 CDS
T01600
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
clc
Caldicellulosiruptor acetigenus 6A
Pathway
clc00290
Valine, leucine and isoleucine biosynthesis
clc00620
Pyruvate metabolism
clc01100
Metabolic pathways
clc01110
Biosynthesis of secondary metabolites
clc01210
2-Oxocarboxylic acid metabolism
clc01230
Biosynthesis of amino acids
Module
clc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
clc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Calla_1214
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Calla_1214
Enzymes [BR:
clc01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Calla_1214
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Ecm33
Motif
Other DBs
NCBI-ProteinID:
AEM73843
UniProt:
G2PX64
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All DBs
Position
complement(1267705..1269285)
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AA seq
526 aa
AA seq
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MENNKTIIIYDSTLRDGAQAGGISYTLEDKLKIVERLDKFGVKFIEAGNPGSNIKDQEFF
ARVKKMRLKNAKLIAFGSTRRVGIDVKDDPNIQSLIAADTEAVAIFGKSWDFHVKEVLKT
TEDENLQMIYDTIKYLKSLGKYVVFDAEHFFDGYKNNKKYALETLKVAKEAGADSLDLCD
TNGGTFPMDIYNITKEVVEMFPGTLIGIHCHNDTGMAVANSIMAVLAGARQVQGTINGYG
ERCGNADLITLIPNLQLKLGFKCVPDENIKHLTSLSRYVAEIANMIPNERAPYVGAYAFT
HKAGMHIDAVKKNPASFEHINPEVVGNARRIVLSEVAGRATILDKIREIDPTVTKDSPVT
KEIIDELKRLENEGYQFESAEASFEMLIRKKLGLYQPFFTLKEFKVLINEPAVEYSSSAI
VKIAVDGVTAITAAEGDGPVHALDNALRKALEKFYPELKEVHLVDYKVRVLNAETATAAK
VRVLIESTDGKDTWTTVGVSTDIVNASWIALVDSLEYKLCKEKVGK
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
gtggaaaataataagaccattatcatctatgactcaaccttaagagacggtgctcaggct
ggtggaatttcatatactctggaagataagctcaagattgtagagaggcttgacaaattt
ggtgtaaagtttatcgaggcagggaatcccggttctaacatcaaagaccaggaatttttc
gcaagagttaaaaagatgagattgaaaaacgcaaagcttatcgcctttggttcaacaagg
cgagtgggaattgacgttaaagatgaccctaacatccagtcgctaattgctgctgacacc
gaagctgttgcaatctttggcaagtcgtgggattttcatgtcaaagaggtcttgaaaaca
acagaggacgaaaatcttcagatgatttatgacactataaaatatttaaagtctttgggc
aagtatgttgtatttgacgcagagcacttttttgatggctacaagaataacaaaaaatac
gctttggagactttaaaggttgcaaaagaggcaggtgcagattctttagacctgtgcgat
acaaacggtggcaccttcccaatggatatttataacatcacaaaagaagttgttgagatg
tttcctgggacattaattggaattcactgtcacaacgacacaggtatggctgttgcaaac
tcaatcatggcagttttggcaggagcacgtcaggttcagggaactataaacggatatggt
gagagatgtggaaatgcagaccttatcacgctcataccaaatcttcagctaaagcttggc
tttaaatgtgtaccagatgagaacataaaacacctgacatcactttcaaggtatgttgca
gagattgccaacatgattccaaacgaaagagcaccatatgttggagcttatgcatttact
cacaaggccggaatgcacattgatgctgtcaagaaaaatccagcctcttttgagcatatc
aatcctgaggttgttggaaatgcaagaaggatagtactgtctgaggttgcaggaagggct
acaattcttgacaagattcgcgagattgacccgacagttacaaaagactcacctgtgaca
aaagagattattgatgagctaaagcgccttgaaaatgaagggtatcagtttgagtctgca
gaggcttcatttgagatgttaattagaaaaaagctggggctttaccagccgttctttact
ctcaaagagtttaaagtgctcattaacgagccggcagtagagtacagctcatctgcaatt
gtaaagattgcggtagatggggttacagcaatcactgctgcagaaggtgatggccctgtt
catgctttagataatgctttgagaaaggctttggaaaaattctacccagagctaaaagag
gtgcatcttgttgactataaagtgcgggtactgaatgcagagactgcaactgctgcaaag
gtaagagttctgattgagtcaacagacggcaaagacacctggacaactgtaggtgtttca
accgacattgtaaatgcaagctggattgcacttgttgactcactggagtataagctttgc
aaagaaaaagtggggaaataa
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