Cellulosilyticum lentocellum: Clole_2333
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Entry
Clole_2333 CDS
T01448
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cle
Cellulosilyticum lentocellum
Pathway
cle00300
Lysine biosynthesis
cle00550
Peptidoglycan biosynthesis
cle01100
Metabolic pathways
cle01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cle00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Clole_2333
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Clole_2333
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Clole_2333
Enzymes [BR:
cle01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Clole_2333
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADZ84041
UniProt:
F2JSA4
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Position
complement(2557392..2558762)
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AA seq
456 aa
AA seq
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MKLDIQDIISAVGGKCIQEGLIKQPIEVITTDSRSQVTNGLFVPLKGDRFDGHEFIKSVY
EKGVIATLTMEDKVIDPRLWTIKVEDTRQALLDLGHYYRNQFTVPVVGITGSVGKTSTKE
MVAAVLSGKWHVHKTDGNFNNEIGLPLTLFKMDASHEAAVIEMGMNHFDEIHRLSLAAAP
EVAVITNVGTSHIENLGSREGILKAKLEILDGLMPGGLLVLNGDNDLLSTVGELPFNKVT
YGLNTSNDYYAEAIANEGEYTTAIVTTPQYKCNIRIKALGEHMVYNTLAAIAVAQYLGLS
KAEIQKGLESYAPAKMRMHLETYDNQITVIDDTYNASPDSMEAALKVLRDYDTKGRKIAV
LGDMFEMGEFAPELHKKVGAFAAEIGIDRVYAVGTLAEYIFKGAKEQEGAPTFYYPTKEA
FIEVMQRELQAEDTVLFKASRGMHFEEMLEAVRKVK
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgaaattagatatacaagacattatatcagctgtaggaggcaaatgtattcaagaaggt
ttaataaaacaacctattgaggtgattacaacagactcaagaagtcaggtaacaaatggt
ttatttgtacccctgaaaggtgatcgctttgatggacatgagtttattaaaagtgtatac
gaaaaaggagtaattgccaccttaactatggaggataaagtgattgacccccgtttatgg
actattaaggtagaggatacgagacaagcgttactagatctaggacattattatagaaat
caatttacagtaccagttgtaggaattacaggtagtgtaggaaaaacaagtacaaaagag
atggttgcagctgttttaagtggcaagtggcatgtgcataagacggatggtaatttcaat
aatgaaataggtttgccacttaccttatttaaaatggatgcatcacatgaagctgcggtt
atcgaaatgggcatgaatcattttgacgaaattcatcgattaagtttagcagcagcacca
gaagtggcagttattactaatgtgggaacctcacatattgagaatcttggaagtagagaa
ggtatcttaaaagcaaagcttgaaatattagatggtttgatgccagggggcttattagta
cttaatggtgataatgaccttttaagtacagtgggtgaattaccttttaataaggtgact
tacggtttaaatacaagtaatgattattatgcagaggctattgccaatgaaggagaatat
actactgcaatagtgacaacaccgcagtataagtgcaacatacgtattaaggcattagga
gaacatatggtatataatacactggctgctattgctgtcgcccaatatttaggtttaagt
aaggctgaaattcaaaagggattagaaagctatgcaccagcaaaaatgcgtatgcatctt
gaaacttatgataatcaaataacagttattgatgatacttacaatgctagtcctgactct
atggaggcggcccttaaggtacttagagattatgatacaaagggaagaaaaatagcagtg
ttaggtgatatgtttgaaatgggggaatttgccccagaacttcataaaaaggtaggagca
tttgctgctgaaatagggattgatagagtttatgcagtagggactctagcagaatatatt
tttaagggtgccaaagaacaagaaggtgcaccaacattttattatccaacgaaagaagcg
tttattgaagtaatgcaaagggaacttcaagcagaagataccgttttatttaaggcatct
agagggatgcattttgaagaaatgctagaagcagtaagaaaggtgaagtga
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