Mageeibacillus indolicus: HMPREF0868_0338
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Entry
HMPREF0868_0338 CDS
T01181
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
clo
Mageeibacillus indolicus
Pathway
clo00300
Lysine biosynthesis
clo00550
Peptidoglycan biosynthesis
clo01100
Metabolic pathways
clo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
clo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HMPREF0868_0338 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HMPREF0868_0338 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HMPREF0868_0338 (murF)
Enzymes [BR:
clo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HMPREF0868_0338 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
MFD_D3
Motif
Other DBs
NCBI-ProteinID:
ADC91662
UniProt:
D3R0G9
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Position
complement(1490744..1492405)
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AA seq
553 aa
AA seq
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MDPIRLKELIRATSGQLFFSADSAMRKEAMNYVLLGTSTDSRTIKRCEAFFALKGENFDG
HAFVERAVRAGAVALVVSDLKCAELWQAELPTILVEDTLTALQKLAAYYRQNYLHTLVAI
TGSVGKTSTREMIAAALRPTLAVSCTGENLNNEIGVPQTVLKVRSACDVAVVEMGMDHAG
DLTKLSRLAQPDIAVITNIGYCHIEQLGSQMAIMRAKAEIINGLKADGVLLLNADDPFLR
QLAAEQKGKIKQAFVALNTCPPDLPGDCLVATDVKIEVDGCASFIIKLQQAPDLEKYGTM
EAFVDSNRLPRIKLPVPGEHHVINALFGLATAHLLHQPLTLAANGLRDFSVIGNRQRIMN
ADGVVLINDTYNAAPESIRAGVKTLCFLAHSEKRRAIAVLGGIAELGNMADRLHYELGRY
LATADLAEIWLCGPYVAAVAQGIADGDQAGDQADSQAGGKGDRSPGASGTEPAVDLASES
VALTATNYTSESRARAEATIKPPVKVHVFADRDSLTAELLPTIQDRDIILIKGSHSFAME
KVCDAIISKRLAE
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atggatccgataagattaaaagaactgataagggcaacctccggtcaactgtttttttca
gctgactcggctatgcggaaagaggccatgaattatgttttgctcggcacttcaaccgac
agccggacgataaaaagatgcgaagcattttttgccttaaaaggggaaaactttgacggc
catgcttttgttgaacgagccgtgcgagccggagcagtagccttggtagtcagcgatctc
aagtgcgccgaactttggcaggctgaattgccgactatattggtcgaggatacattgacc
gctttgcaaaaattggcggcttattatcgtcaaaactatttgcataccttggtcgctatc
actggtagtgtcggcaaaacgtcaacccgggaaatgattgccgccgctttgcgaccgact
ttggcggtttcctgtacaggcgaaaatctgaataatgagatcggcgtgccgcaaaccgtc
ctgaaagttcgcagtgcttgtgatgtcgctgtcgttgaaatgggcatggatcacgccggc
gatttgactaaattaagcagattggctcagccggatattgcggttattactaatataggg
tactgccatattgagcaacttggctctcaaatggccataatgcgggctaaggcggaaatt
attaacgggctgaaagcggacggagtgttgttgcttaatgctgatgatccgtttttgcgt
cagttggccgcggaacaaaaaggcaagattaaacaagcttttgtggcactaaatacttgt
ccgccggatctgcctggggactgtctcgttgctactgatgtgaaaattgaagtcgatggt
tgtgcgtcttttattataaaacttcagcaagcgcctgacttagaaaaatacgggaccatg
gaggcttttgtcgatagcaatcggctgccccgtataaaattaccggtgccgggggagcat
catgtgataaacgccctcttcggcttagcgacggctcatctgttgcatcagccgctcact
ttagcggccaacggtttgcgcgatttctcggtaatcgggaatcgtcagcggattatgaac
gcggacggagtggtgttgatcaacgatacctataacgccgcgccggagtcaatacgagcc
ggggtcaagactttgtgtttcttagcacattcagaaaagcgccgggcaattgcggtgtta
ggtggtattgctgagcttggaaatatggcggatcgattgcattatgaattggggcggtac
ttggcgacagccgacttggcagaaatttggctctgcggtccatacgtggccgcggtggct
caaggaatagctgatggtgatcaggctggcgatcaggccgacagtcaggccggcggcaaa
ggagatagaagccccggagcttccggcacggaaccggcagtggacctcgcttcagaatcg
gtggcacttacggccacaaattacacttcagaatcgagggcgagggctgaggcgacgatt
aagcccccggtcaaagttcatgttttcgccgaccgtgacagtttgaccgcggaactattg
ccgacgattcaagaccgtgacatcattctgattaagggttcgcattcttttgcgatggaa
aaagtgtgtgatgccatcatcagtaaacgcttggccgaataa
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