Canis lupus dingo (dingo): 112643458 Help Entry 112643458         CDS       T08371                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism clud  Canis lupus dingo (dingo) Pathway clud04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:clud00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     112643458 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:clud03036]     112643458 (SYNE1) Chromosome and associated proteins [BR:clud03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     112643458 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH Spectrin_SYNE1_2 SYNE3 Bromo_TP Motif Other DBs NCBI-GeneID:  112643458 NCBI-ProteinID:  XP_035564280 LinkDB All DBs Position 1:complement(42373407..42822703) Genome browser AA seq 8833 aa AA seqDB search MATSRTTSRSPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPLVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINSTD IADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSGSTSSVDSMVSAETASPPSKRKVA TKIQGNAKKALLKWVQYTVAKQTGTEVKDFGRSWRSGVAFHSVIHAIRPELVDLEKVKGR SNRENLEEAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNTGTDGQ ENDEILPGFPSFANSIQNFKREDRLILKETKVWIEQFERDLTRAQMTESNLQDKYQSFKH FRVQYEIKRKQIEHLIQPVHRDGKLSLDQALVKQSWDRVSSRLFDWHIQLDKSLPAPLGT IGAWLYRAEVALREEITIQQVHEETANTIQRKREQHKDLLQNTDAHKRAFHEIYRTRSVN GIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRR ESVELLLQNYISFIENTKFFEQYEVTYQILKQTAEMYIQADGSVEEAENVMKFMNETTAQ WRNLSVEVRSVRSMLEEVIANWDRYGNTVASLQAWLEDAEKMLNQTEHAKKDFFRNLPHW IQQHAAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYARADELDRMKKEY TDCVNALSDFAMGAHKKLSEPLEVSFLNVKLLIQDLEDIEQRVPVMDAQYKMITKTAHLI TKESSQEEANEMFATMSGLKEQLTKVKDCYSPLLYESQQLLIPLEELEKQMTFFYDSVGK INEILTVLEHEAQSSAVFKQKQQELSACQESCKKTMTQIEKGSQNVQKFMTLSSVLKHFD QTKLHRQIADAHGAFQNMMKKIGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEK GNPEDLLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQG EAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLVPQEGSEKIIKEHRIFFSDKGPHHV CEKRLQLIEELCLKLPGRDPVRNTPETCHVTLKELRAAIDTTYMKLVEDPDKWKDYTSRI SQFSSWISAKETELKGFKNEPIDTANHGKVKHAVEEIRNDVTTKGETLNWLKSRLKVLIE VSSENEAQKQGDELAKLSGSFKALVALLSEVEKMLSNFGDCVQYKEIVKSSLEELISGSK EIQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIEQAQQGEGGLPGQVREE LRKLESTLDNMEHSREKQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSYSSLE SLSSELEQTKEFSKRTEGIAVQAENLVKEASEIPLGPKNKQLLQQQAKSIKEQVKKLEDT LEEDIKTMEMVKNKWDHFGNNFETLSIWITEKEKELNALETSSSAMDMQIHQIKVIIQEI QSKLSSITELEESAQSFAQFVTTGESARIKAKLTQIRRYWEELREHAQCLEGTILGHLSQ QQKFEENLRKIQKSVSEFEDKLADPVKICSSATETYKVLQEHMDLCQALEALSSTVATTS ASAQKVANRGSCVQEAAALQQRYQEMQSQAKEKQTALEKLLAHWQRLEKELSTFLTWLER CEAITSSPEMDISSDRVKVESELQSIQALQNEVVSQASVYSNLLQLKESLFSVASKDDVK MMKLHLEQLDERWRDLPQIISKRIAFLQSVVAEHQQFDELLLSLSVWIKLFLSELQSTSE ISITDHQAAFTRHKDHAAEVESKKGELQSLQDHLVKLGALVRAESLPLLQGKAEDCFQLF EEASQVVERRQLALAQLAEFLQSHVSLSGVLHRLRHTVEATNSMNRKQTDLLEKDLNHAI QDAKSLESVAISLDSVLAKAQYHLKSGSSEQRTSCRTTADHLCSELERIQNLLGIKQSEA DALAVLKKAFQDQKEELLKSIEDIEERTDKERLKELTRQALQQRLRVFNQLEDELNSHEH ELCWLKDKAKQIAQKDVAFASEVDREVNRLEVTWDDTKKLIHENQGQCCGLIDLIREYQN LKSAVSKVLENASNVIATRTTIKDQEDLKWALSKHETAKNEMCNKQKELDNFTSKGKQLL FELKKIHSSDFILVKTDMDSTVDRWLDISEKIEENMDRLRVSLTIWADVLSSKDEIDGWC NSSVPRLAESISNLNNSLRAEEFLKEFESEVKNKALRLEELHCKVNDLKELTKNPETPPD LQFVEADLRQKLEHAKEITEEAKGTLKDFTAQSTQVEKFINDITSWLTKVEESLMNCAQT ETWEGLKKVKEIQKELQSQQSNISSTQENLNSLCRKYHSVELESLGSALTGLIKNQEAVS QLCSKTQASLQDSLVKHFNESMQEFQEWFSGIKTAAKESSDRTGDSKVLEAKLHNLQNIL DSISDGQSKLDAVTQEGQTLYAHVSKQIVGSIQEKITKANEEFQAFLKQCLKDKQTLQDC ALELGSFEDQHRKLNLWIHEMDERLSTENLGESKQHIPEKKNEVHKVEMFLGELLAARES LDKLSQRGQLLSEEGHGAGKEGRLCSQLLTNYQNLLRMTKEKLRSCQVALQEHEALEEAL QSMWSWVKAIQDRLAGAESTIGSKDTLEKRLLQIQDILLMKGEGEVKLNMAIGKGEQALR SSNKQGQKVIQTQLQTLKDVWADIMSSSVHAQSTLESVISKWNDYLEWRNQLEQWMESVD QKVEHPLQLQPGLKEKFSLLDHFQSIVSEAEDHAGALQHLTSKSRELYQKTENESFKETA QEELKTQFNDIITVSKEKMRKAEEIVKDHLMYLDAVQEFTDWLHSAKEELHRWSDMSGDS SATQKKLSKIKELMDSREIGASRLSRVELLAPTVKQNTSASGCELVDTEMQALRADWKQW EDSVVQTQTSLENLVSQMALSEQEFSGQVAQLEQALEQFSALLTTWAQQLALLEGKNTDK EIVECWQKGQEILDALQKAEPKTEDLKSQLNELCRFSRDLSTYSGKVSSLIKEYNCLCLQ ASKGCQNREQILQQRFRRAFKDFQQWLVNAKITTAKCFDIPQNINEVSTNLQKIQEFLSE SENGQHKLNMMLSKGELLSTLLTKEKADGIQAKVVTAKEDWKNFHSNLHQKESALENLKI QMKDFEVSAEPVQDWLSKTEKLVQESSNRLYDLPAKRREQQKLQSVLEEINCYEPQLNRL REKAQQLWEGQAASKSFMHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQ DWLTDAVHMLDSYCHPTSDKSVLDSRMLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSP EGIPAIQQQLQSVKDMWASLLSAAIRCKSQLEGALSKWTSYQDDVRQFSGWMDSMEASLN ESERQYAELREKTSALGKAKLLSEEVLSYSSLLETIELKGAGMTEHYVTQLEFQDLQERY RTIKERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQENLDRHSVLEGDAHTHETTLR DLQELQVRCAEGQALLNSVLHTREEVIPSGIPQTEDRALESLRQDWQAYQQRLTETRTQF NNVVNKLRLMEQKYQQVDEWLKTLENKVKVRTGRQSNRAAKEIQLHQMKKWHEEVTAYKD EVEEVGARAQEMLDENHVSSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESELS LNSYSDWYTSTHKNFKNVATKIDRVDKAMMGKKMKMLEGLLKDMEKGHSLLKSTREKGER ALKYLEDSEAETLRNEIHEHMEQLKELTSTVRKEHMTLEKGLLLAKEFSDKYKALTQWIS EYQEILHTPEEPKMELYEKKAQLSKYKSLQQMVLSHEPSVKSVREKGEALLELVQDVTLK DEIDKLQSDYKDLCDAGKEHVCSLETKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLMET SSLETITQQLAHHKAMMEEIAGFEDRLNNLKIKGDNLISQCADHLQAKLKQNVHAHLQGT SDSYSAICSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLKPSQLPPLSRAEAV KQVKHFRALQEQARTYLDLLCSMCDLSNSSVKTTAKDIQQTEQMIEQRLAQAQNLTQGWG EIKHMKAELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQCKQASVTAIT ERVNKLTKKQESPEHKEISHLNDQWLDLCLQSNNLCLQREEDLQRTRDYHDCMNVVEVFL EKFTTEWDNLARSDAESTAVHLEALKKLALALQERKQAIEDLKDQKQKMIEHLNLDDKEL VKEQTSHLEQRWFQLEDLVKRKIQVSVTNLEELNVVRSRFQELMEWAEEQQPNISEALKQ SPPPDVAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQIIQKALSDAQSH VNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQV KTCKSAQASLKTYQNEVTGLWAQGRELMKGATEQEKSEILGKLQELQSVYDTVLQKCSHR LQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESAELHTQLAKYQHILEQSP EYENLLLTLQRTGQAILPSLNEVDHSYLNEKLNALPLQFNVVVALAKDKFYKVQEAILAR KEYASLIELTTQSLSELEDQFLKMNKVPTDLIVEEALSLQDGCRALLREVSGLGEAVDEL NQKKESFRSTGQPWQPDKMLHLVTLYHRLKRQAEQRVNLLEDTTSAYQEHEKMCHQLEKQ LEAVKTEQSKVNEETLPAEEKLKMYHSLAGSLQDSEIILKRVTVHLEDLVPHLDPLAYEK AKQQIQSWQEELKLLTSAIGATVTECESRMVQSIDFQTELSRSLDWLRSVKAELSGPVCL ELSLQDIQEEIRKIQIHQEEVQSSLRIMNALSNKEKEKFTKAKELISADLQHTLAELSEL DGDIQEALRTRQAALTQIYSQCQRYYQVFQAANDWLEDAHEMLQLAGNGIDVESAEENLK SHMEFFSTEDQFHRNLEELQGLVASLDPLIKPTGKEDLAQKMASLEDKSQRIIQDSHAQL DLLQRCAAQWQDYQKAREEVIELMNDAEKKLSEFSLSKTSSSHEAEEKLSEHKSLVSVVN SFHEKVVALEDKTSQLEKTGNDASKAAISRSMTTVWQRWTRLRAVAQDQEKILEDAVDEW KSFNNKVKKATEIIDQLQDKLPGSSAEKASKAELLTLLDFHDTLILELEQQQLALGLLRQ QALSMLQDGATKSPGEEPSIVQEITTMQDRCLNMQEKVKSNGKVVKQELKEREVVETQIN SVKSWVQETKEYLGNPTIEIDAQLEELQILLTEATNRRQNIEKMTEEQKNKYLGLYSILP SEVSLQLAEVALDLGTIHDQIQDKVREVEQSKAMSQEFSRQIQKIAKDLTTILSKLRAKT DNLAQAKSDQKVLGEELDGCNLKLMELDAAVQKFSEQNGQLGKPLAKKIGKLTELHQQTI RQAENRLSKLSQAASHLEEYNEMLEFILKWIEKAKVLVHGKITWNSANQLREQYVLHQTM LEESEEIHSNLEAMIVKLQYLASVYSTEKMSQQVAELGRESEELRQMIKIRMHNLQDAAK DMKKFETELKNLQVALEQAQTTLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVHAVQIC QSALRIPEDVVTSLPLCHAALHLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMQHLRE LIEGAHREIEDTPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHA TMLLTVTEVEGLAEGTEDLDRELLPATSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSE ISSPPACRSPSPVANADASVNQDIAYYQALSAERLQTDAARIHPSTLPSQEFYEPGLEPS ATAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIEMKLSESLEH GRSPESQMAEHQSSSQALMDEILMLQDEISELQSSLAEELVSESPESDPAEQLALQSTLT VLAERMSTIKMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDHWLLSTKATLDT ALGTAKEPMDMEAQLVDCQNMLLEIEQKVVALSELSVHNDNLLLEGKAHTKEEAEQLAIK LRVLKGSLLELQRALHDKQLNIQQGTAQEKEESHVDLTASQSPGVQEWLAQARTTWTHQR QSSLQQQKELEQELAEQKSLLRSVASRGEEILTQHSAAETSGGAGEKPDVLSQELGMEGE KSAAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQLLYSRPNRLLSGVPLYKGDGQTQD KSAVTSLLDGLNQVFEEVSSQSGGKKRQNIHLEQKLYDGVSATSTWLDDVEERLFVATAL LPEETEACLFNQETLAKDIKEMSEEMDKNRNLFSQAFPENGDNRDVIEDTLGCLLGRLSL LDSVVNQRCHQMKERLQQILNFQNDLKVLCTSLADNKYIILQKLANVFEQPVAEQIEAIQ QAEDGLKELDAGIIELKRRGDKLQIEQPSMQELSKLQDMYDELMMTIGSRRSGLNQNLAL KSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETL FRKIISFAVPQETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDYQELSRQLEV VESSIPSVGLVEESEDRLIDRIALYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLEG QLNQLGEHWLNNTNKVSKELHRLETVLKHWTRYQSESAELIHWLQSAKDRLEFWTQQSVT VPQELEMVRDHLNAFLEFSKEVDAKSSLKSSVLSTGNQLLRLKKVDTAALRSELSHIDSQ WTDLLTNIPTVQEKLHQLQMDKLPSRHAISEVMTWISLMENVIQKDEENIQNSVGYKAIH EYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQ GLVTEKIQLLEGLLESWSEYENNVQSLKTWYETQENRLKQQHRIGDQASVQNAMKDCQDL EDLVKAKEKEVERIEQSGLALIQNKKEEVSGIVMSTLRELNQTWANLDHMVGQLKILLKS VFDQWNNHKVAFDEINTYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQEKNL QRFGSITNQLLKECHPPVTETLTNTLKDVNMRWNNLLEEIAEQLHSSKALLQLWQRYKDY SQQCASTVQQQEDRTNELLKAATNKDIADDEAATWIQDCNDLLKGLGIVKDSLFVLHELG EQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTTLQVGVLDYETFTKSLEALEAW IVEAEDILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMVPDLDRLNELGYRLPLNDKEI KRMQNLNRRWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNY QHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGV IRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPVSALGSVPIPLQQARTLFDEV QFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTEIQEKWKSASVRLEEQKKK LAFLLKDWENCENGIADSLEKLRTFKKKLSQPLPDHHEELHAEQMRCKELENVAGSWTDD MAQLTLLKDTLCAYISADDISILNERMELLQRQWEELCHQLSLRRQQVSERLNEWAVFSE KNKELCEWLTQMESKVSQNGDILIEDMIEKLKKDYQEEIAVAQENKIQLQQMGERLARAS HESKASEIEYKLGKVNDRWQHLLDLMAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESE LAKPIVYDSCDSDEIQKKLTEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECD SIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKISERTAAFPSS SGVLYTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQ RWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIK QLKAFQQEISLNHNKIEHIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYH KKLIRLPLPDDDHDLSDRELELDDSAALSDLHWRDTSADSVLSPQPSSNPSLSLAQPLRS ERSGRDTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEGQDDKDFYLRGAVGLSDV MIPESPEAYVKLTESAIRNTSGAPSALESQIRQLDKALDESRFQMQQTENIIRSKTPTGP ELDSSYRGYMKLLGECSGSIDSVKRLEHKLREEEENFPGFVNLNSTETQTAGVIDRWELI QAQALSKELRMKQNLQKWQQFNSDLNNIWTWLGETEEELEQLQRLELSTDIQAIELQIKK LKELQKAVDHRKALILSINLCSSEFTQTDSEKSQDLQDRLSQMNGRWDHVCSLLEEWRGL LQDALMQCQDFHEMSHGLLLMLENIDRRKNEIVPIDSNQDAETLQDHHKQLMQIRHELLE SQLKVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDMSS SQQDLSSWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGS DSSLSEPRPARSGRAFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSF HPMLRYTNGPPPL NT seq 26502 nt NT seq  +upstreamnt  +downstreamnt atggcaacttccaggacgacctcacggtctcctcgggacattgccaatgtgatgcagagg ctgcaagatgagcaagagatagtacaaaaacgtacttttacaaaatggatcaactctcat ctggccaagcggaaacccccactggtggtagatgatctttttgaagacatgaaagatggt gttaagctgcttgcgcttctggaggttctgtccgggcagaaattgccttgtgaacaagga cgccgtatgaagcggatccatgctgttgctaatattggcacagcactcaagttccttgaa ggaaggaagtccatgtacagaggatcaccgattaaattagtcaacattaactccactgat atagctgatggccgaccatcaatagttcttggattgatgtggaccattattctgtatttc cagattgaggagttgaccagcaacctgccacagctgcagtctctgtctggcagcacatcc tctgtggatagcatggttagtgctgagactgccagccccccaagtaaacggaaagtggcc accaagattcaaggaaatgctaagaaggctttattaaagtgggtccagtacacagtagcc aagcagacaggaacagaagtaaaggactttgggcggagttggagaagtggggttgccttc cattccgtgatccatgccattcggccagaactagtggacttggagaaagtgaaagggaga tctaaccgggaaaacctggaggaggctttcactattgctgaaacagaactaggaatcccc agactgttggatcctgaagatgttgacgtggataaaccagatgagaagtctattatgacc tatgtagcccaatttctgaagcattaccctgacatccacaacacaggcactgatgggcaa gaaaatgatgaaatacttccaggttttccatcttttgcaaattctatccaaaattttaag agagaagacaggctaattttgaaggaaacaaaagtttggatagaacaatttgaaagagat ttgacaagggcacagatgacagaatcaaatttgcaagataaatatcagtcatttaagcac ttcagagttcaatatgaaataaaaaggaaacagattgaacatttaatacaaccagtacat agagatggtaaactgtcacttgaccaagcattggtaaaacaatcctgggacagagtgtcc tccaggctctttgattggcatatacagcttgataaatctctccctgcacctctgggcact ataggtgcctggttatacagagcagaggtagctctgagggaggaaattaccattcagcag gtccatgaggaaacggccaacacaatacaacggaaacgtgagcaacacaaggatctgctt caaaacacagatgcccacaaaagagcattccatgagatctaccggaccaggtctgttaac gggatcccagtgccacctgaccaattagaggacatggcagaaaggtttcattttgtttcc tccacatcagagctacacttaatgaaaatggaatttctagaattaaagtaccgtctgctc tcactgctggttcttgcagagtcaaagctgaaatcttggatcatcaagtatgggaggaga gagtcagtggagctgcttctgcaaaactatatctcttttatagaaaataccaagttcttt gaacagtatgaagtgacataccagatcttaaaacagacagcggagatgtacatccaagct gacggttcagtggaagaagctgagaatgtgatgaaattcatgaatgaaaccactgcccag tggaggaacctctcagtggaagttaggagcgtgcggagcatgcttgaagaagtcatcgct aactgggatcgatatggcaatacggtggccagtcttcaggcctggctggaggatgctgag aaaatgctaaatcagacagagcacgctaaaaaggattttttccgaaatttgcctcactgg atacagcagcatgctgccatgaatgatgcaggcaattttctaattgaaacatgtgatgag atggtttcccgagaccttaaacagcagttgctattgctcaatgggcgatggagggagttg ttcatggaagtcaagcaatatgctcgggctgatgagctggacagaatgaagaaggaatac acagactgtgtcaatgctctgtcggattttgcaatgggagcccataagaaactttccgaa cccttagaagtctcttttcttaatgtcaagctattaattcaagacttggaggacattgag cagagggtgcctgtaatggatgctcaatacaagatgattacaaagactgcacacctcatt accaaagagagttcccaagaagaagctaatgaaatgtttgcaaccatgtctgggctcaaa gaacagctaaccaaggtcaaggactgttactctccactcctttatgagtctcagcagttg ttgataccattggaagaattagaaaagcagatgacattcttttatgactcagttgggaaa atcaatgaaattttaacagttcttgagcatgaggcacaatctagtgctgtttttaaacag aaacaacaggaactgtcagcttgtcaagaaagctgtaagaaaaccatgacacaaattgag aaaggcagtcaaaatgttcaaaagttcatgaccttgagcagtgtgttaaagcattttgat cagacaaagctgcacagacagattgcagatgcccatggtgctttccagaatatgatgaag aaaattggagactggaagaaacatgtggaaaccaatagtcgtttgatgaagaaatttgag gagtctcgagcagagttggagaaggtgctgcggatagctcaggagggcttggaagaaaag ggaaatccagaagacctcctgaggagacatactgagttcttcagccagctggaccagaga gtgctcaatgctttcctgaaagcttgtgatgagctcaccgacattctccctgagcaggaa cagcagggcctacaggaagctgttagaaagctccacaaacagtggaaggatcttcaagga gaagccccatatcatttgcttcatctgaagattgatgtggagaagaatagattcttagct tctgtagaagaatgcaggactgagctggatcgagagaccaagctggtgccccaggaaggc agtgaaaagattattaaagaacacaggattttcttcagtgacaaaggtcctcatcatgtt tgtgagaaaaggttacagcttattgaagaactgtgtctgaagctcccaggccgggaccca gtaaggaacacacctgaaacctgtcacgtgactctcaaagagctcagagctgccattgat accacctatatgaagctcgtggaggacccagacaagtggaaggactatactagcagaatt tctcagttctcatcttggatatctgcaaaggagacagagttgaaagggtttaagaatgag cccatcgatactgccaaccatggaaaggttaaacatgctgtagaggagatcagaaatgat gttaccacaaagggcgagactctcaactggctgaaatccaggcttaaagttttaattgaa gtttcttctgagaatgaagcccaaaagcaaggagatgagctggcaaaattatctggttct ttcaaagctcttgtagctttgttgtcagaggttgaaaagatgttaagcaactttggggac tgtgtccagtacaaagaaatagttaaaagctcccttgaggagttaatttctggctctaaa gaaatccaggaacaagctgagaagatcctggacactgaaaatctgtttgaagcacagcag ttacttcttcatcaccagcaaaagacaaagaggatttctgcaaagaagagagatgtgcag cagcagatagagcaggctcagcagggagaaggtgggctgccgggccaagtccgggaggag ctgcggaagctggagagcaccctggacaacatggagcacagcagggagaaacaggaacgc cgcatccaggtcacattaagaaagtgggaacgatttgaaacgaacaaagagacagtggtc agatacctttttcaaacaggttccagccatgagcgcttcctgagttatagcagtttggaa agtttatcttcagaattggaacagacaaaggagttttctaaacgaacagaaggtattgca gtccaggctgaaaatcttgtgaaggaagcttctgagataccacttgggcccaaaaataag cagctgcttcagcagcaggccaagtcaatcaaagagcaagtcaaaaaattagaagacaca cttgaagaagatattaaaaccatggaaatggtgaaaaacaagtgggatcattttggcaat aattttgagaccctgtccatctggataactgagaaagaaaaagaactcaatgccttggaa acttcgtcatctgccatggacatgcaaatccaccagattaaggtcataattcaggaaata 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acaaccttgacttctccagaagtgggccgtcttagtctcaaggagcaactttctcatcga cagcatttgttatctgagatggagtcactcaagccaaaggtccatgctgtgcagatttgc cagagtgcactgaggatccctgaagatgtggttaccagcttgccactgtgccatgctgct ctgcacctgcaggaggaggccagccggttacagcacacagcaatccagcagtgcaacatc atgcaggaggctgtggtgcaatatgaacagtatgagcaagaaatgcagcacctccgggag cttatagaaggagcgcacagagaaatcgaggatacacctgtggccaccagtaacatccag gagctgcaagcccagatttctcggcatgaggagctggctcagaaaatcaagggctaccag gagcagatcgcctctttgaactccaagtgcaagatgctgacgatgaaagccaagcatgcc accatgctgctgacggtcacggaggtggaggggctggcggaggggacggaggacctggac agggagctcctccccgcgacctcggcccacccctctgtggtcatgatgactgcaggtcgt tgtcacactttgctgtcacctgtgacggaggagtctggggaggagggaaccaacagtgaa atttcctctccacctgcctgtcgctccccttcacctgtggctaatgcagatgcctctgtt aaccaggacattgcttattaccaagcactatctgctgagaggttacagactgatgccgca aggatccaccccagcacgttgccatctcaggagttctacgaaccaggactggagccatct gctactgctaaactggacgatttgcagcgttcttgggaaaccttaaagaatgtgataagt gaaaagcagcgcactctctatgaagctttggaacgccagcagaagtaccaggactcccta cagtccatctccacaaagatggaggccattgagatgaaactcagtgagagtctggagcac ggcaggagtccagaaagccagatggctgaacatcagtcttcttcacaggcactgatggat gagattctcatgcttcaagatgagatcagtgagctccagtcgtctctggcagaggagctg gtgtccgagtctcccgagtccgaccccgctgaacagctagccttgcagtccacactcact gtcttagctgagcggatgtccaccatcaagatgaaggcatcagggaagcgacagcttttg gaggagaagttaaatgatcagcttgaggaacagagacaggaacaggccctgcagaggtat cgctgtgaagccgatgagctggaccactggctcttgagcactaaagccactttggacaca gcactgggtacagcgaaggagcctatggacatggaagcccagctagtggactgccagaac atgctgttggaaatagagcagaaggtggtggccttatcagaactctcagtccacaatgac aacctgctgctggaaggcaaggctcacaccaaggaggaggctgagcagcttgccataaag ctgagagtgctcaaggggagcctcctggagctgcagagagccctgcacgacaaacagctc aacatccagcagggaacagcacaagagaaggaggagagccatgtggacctgactgccagc cagagccctggtgtccaggaatggctggcccaagcgcggaccacgtggacccaccagaga cagagcagtctccagcaacaaaaagagttggaacaggaattagcagagcagaagagcctc ctgcggtcagtggccagtcgtggagaggaaattctcacccagcactcagctgcagagacc tctggtggtgctggcgaaaaacctgatgtgttatcccaggaattggggatggaaggggag aaatcagctgctgaagaccagatgagaatgaaatgggaaagcctacatcaagaatttagt accaagcagaagctactacagaatgttctggaacaggaacaagagcaactgctatacagc aggccaaatcggctcctgtctggtgtgccactatacaaaggggatgggcagacccaagac aaatctgcagtgacatctttgctggatggattgaaccaggtcttcgaagaggtttcatca cagagtggggggaaaaagaggcagaacattcacttggaacagaagttatatgatggggtg tcagctacctccacatggttggatgatgttgaggaacgtttatttgttgccacagcactt ttaccagaagaaacagaagcttgcctcttcaaccaagagactcttgccaaagatattaag gaaatgtctgaagaaatggataagaacaggaacttgttttcccaagcatttccagagaat ggtgataaccgagatgtcattgaagacactttgggttgtcttttgggcaggttgtccttg ctagactcagtagtaaatcagcgctgtcatcagatgaaggaaagacttcagcaaatacta aatttccagaatgatctgaaggtgctgtgtacatcactggctgacaacaaatacatcatt ctacagaaactggcaaatgtgtttgaacaacctgtggcagagcaaatagaggcaatacaa caggctgaagatgggctaaaggaactggatgcaggaatcattgaattaaaaaggcgtggt gacaagttgcagattgagcagccttccatgcaggaactgtccaaacttcaggatatgtat gatgaacttatgatgaccataggctcccggcggagtggtctgaaccagaatcttgcactg aagagtcagtacgaaagggccctgcaagatctggctgacctgctcgagactggacaggag aagatggcaggtgaccagaaaatcattgtgtcttccaaagaggaaattcaacaactactt gacaaacataaggaatattttcagggcctggaatctcatatgatcttgactgaaacactc ttcagaaagataatcagctttgcagtcccacaggaaactcagttccacacagaactgatg gcacaggcttcagctgtactaaaacgggcccacaagaggggtgtggagttggagtacatt ctagagacatggtctcatctggatgaagactatcaggagctcagcagacagctggaggtg gtggaaagtagcatcccgagtgtggggttagtggaagaaagcgaggacaggctcatcgac cggattgcactttaccagcacttgaaatccagccttaatgaataccagcccaaattatat caggtattagatgatgggaaacgactgcttatatccattagctgctcagatctagaaggc cagctaaatcaacttggagaacactggttaaataataccaacaaagtgtctaaggaactt cacagattggaaacagtattgaaacactggaccagatatcaaagcgaatctgcagaactt attcactggttgcaatctgcaaaagacaggctagaattttggactcaacaatctgtgaca gtcccacaagaactggaaatggtccgtgatcatctaaatgccttcctggagttttccaaa gaagtggatgccaaatcttctctgaaatcgtctgtcctcagcactggaaatcagcttctt cgattaaagaaagtagacacagctgccctacgttcagagctgtcacacattgatagccaa tggactgacctgctgacaaatattccaactgtacaggaaaagctccatcagctccaaatg gataagctgccttcccgtcatgccatttctgaagttatgacttggatttctcttatggaa aatgttattcaaaaggatgaagagaatatacaaaattcagtaggttacaaggcaattcat gaataccttcagaaatataagggttttaagatagatattaactgtaaacagttgacagtt gattttgtgaatcagtctgtgctacaaatcagtagtcaggatgtggaaagtaaacgcagt gataagactgattttgctgaacaacttggagccatgaataaaagttggcaaatcctgcag ggtctagtgactgagaagatccagctgttggaaggcttattggaatcttggtcagaatat gaaaataatgtacaaagtctgaaaacttggtatgaaacccaggaaaacagactaaagcaa cagcatcgaattggagatcaggcttcagttcagaatgcaatgaaagactgtcaggatcta gaagatttggttaaagcaaaagaaaaagaggtagagagaattgagcagagtggacttgct ttgattcagaacaagaaagaagaagtctctggcattgtcatgagcacgctgcgggagctg aaccaaacctgggcaaatttagaccacatggttgggcaattaaagatactgctgaagtcc gtgtttgaccaatggaacaatcacaaggtggcctttgatgagataaacacctacctcatg gaggccagatattctctttcccgcttccgtctgctgactggctctttagaagctgtacaa gttcaggtagacaatcttcagaatcttcaagatgatctggaaaaacaggaaaagaaccta cagaggtttggctctatcaccaaccaactgttaaaagagtgtcacccacctgtgacagaa actcttaccaatacattaaaagatgtcaatatgagatggaataatttgctggaagagatt gctgagcagctgcactccagcaaagccctacttcaactctggcaaagatacaaggactac tcccaacagtgtgcttctacagttcagcagcaagaggaccgaaccaatgagctcttgaag gcagccactaacaaggacattgctgatgacgaagctgctacatggattcaagattgcaat gatctcctcaaaggactggggatagtgaaggattctctttttgttctccatgagctggga gagcagctcaagcaacaagtggatgcttcagcggcatcagccattcaatctgatcagctg tctttgagtcaacacctatgtgccctagaacaggctctttgcaagcagcagactacatta caggttggagttcttgactatgagacctttaccaagagtttagaagcattggaggcctgg atagtagaagctgaagacatattacaagggcaggaccctagccactcatctgacctctca accattcaggaaaggatggaagaacttaagggacagatgttaaaattcagcagcatggtc cctgatctagaccgtctaaatgagcttgggtataggctaccactgaatgataaagaaatc aaaaggatgcagaatctgaaccggcgctggtctctgatctcctctcagaccacagaaaga ttcagtaagttgcaatcatttttgctacaacatcagactttcttggaaaaatgtgaaaca tggatggaattcctggttcaaacggaacaaaagttagcagtagagatttcaggcaattat cagcatcttttggagcagcagagagcgcatgagttgtttcaagcagagatgttcagtcgt cagcagattttgcactcaatcattattgatggtcagcgtcttctagaacaaggtcaagtt gatgacagggatgaattcaacctgaaattgacacttctcagcaatcagtggcagggagtg attcgccgggcccagcagaggaggggcatcattgacagccagattcgccagtggcagcgg tacagggagatggcagagaagcttcgtaaatggttggttgaagtgtcctatcttcccgtg agtgctctcggaagtgtcccaataccactgcaacaggcaaggaccctctttgatgaagtg cagttcaaagaaaaagtgttcctgcgacagcaaggcagctacatcctaacagtggaggct ggcaagcagctcctgctctcagcggacagtggggctgaggctgccttgcaggcagaactc actgaaatccaagagaagtggaaatcagccagcgtgcgtttggaggaacagaagaaaaaa ctggccttcttgttgaaagactgggaaaactgtgagaacggaatagctgattctctggag aaactacgaactttcaaaaagaagctttctcagcctcttccagatcaccatgaggagctg catgcagagcaaatgcgttgcaaggagctggaaaatgtagctgggagctggacagatgat atggctcagctgacactgctgaaggatactctctgtgcctacatcagcgccgatgatatc tccatcctgaatgaacgcatggagcttctgcaaaggcagtgggaagaactgtgccaccag ctctccttaaggcggcagcaagtaagtgaaagattgaatgaatgggcagtcttcagtgaa aagaacaaggaactttgtgaatggttgacccagatggaaagcaaagtttctcaaaatgga gacatcctcattgaagatatgatagaaaagctcaagaaggattatcaagaggaaattgct gttgcccaagagaacaaaatacagctccagcaaatgggagaacgacttgctagagccagc catgaaagcaaagcctctgagattgaatacaaactcggaaaggttaatgaccggtggcag catctcctggatctcatggcagccagggtaaagaagctgaaggagaccctggttgccgta cagcagctggataagaacatgagcagcctgaggacgtggctggctcacatcgagtcagag ctggccaagcccatagtctatgattcctgtgactcggatgaaatacagaaaaagcttact gagcagcaggagcttcagagagacattgagaaacatagcacaggcgtggcctctgttctc aacttatgtgaggtcctgcttcatgactgtgatgcctgcgccacggatgcagagtgtgat tccatccagcaggcgacgcgaaacctggaccggcgatggagaaatatctgtgccatgtcc atggaaagaaggctcaaaattgaagagacatggcgattgtggcagaagtttctcgatgat tattctcgttttgaagattggctcaagatttcagaaaggacagctgccttccccagctct tctggggtgctctatacagttgccaaggaagaactaaagaaatttgaggctttccaacga caggtccacgagagcctgacccagctagaactaatcaacaagcagtaccgtcgcctggcc agagagaaccgcaccgattctgcttgtagcctaaagcagatggttcatgaaggcaaccag agatgggacaacctgcaaaagcgtgtcacctccatcttgcgcagactcaagcatttcatt ggccagcgtgaggagtttgagactgcacgggacagcattttggtgtggctgacagagatg gatctacagctcactaatattgagcatttttctgagtgtgatgttcaagctaaaataaag caactcaaggccttccagcaagaaatttcactgaaccacaataagattgagcacataatt gcccaaggagaacagcttatagaaaagagtgagcccttggatgcggcagtcattgaggaa gagctagatgaactccggcgttactgtcaggaagtctttgggcgtgtggaaagataccat aagaaactgattcgcctgcctctcccagatgatgaccatgacctctctgaccgggagctg gagctggatgactctgcagctctctcagacctccactggcgtgacacctctgcagacagc gtgctctctccccagccttcctccaacccctccctctcactcgcccagcccctgcggagt gagcggtcaggacgagacacgcctgccagtgtggactccatccccctggagtgggaccat gactatgacctcagtcgtgacctggagtctgctgtgtctagaactctaccctctgaggat gaagagggtcaggatgataaagatttctacctcaggggagctgttggcttatcagatgta atgatccccgaaagtcccgaggcctatgtaaaactcacagaaagtgcaatcagaaatacc tctggagctcccagtgccttagagtcacagatccgacaactggacaaagcattggatgag agccgttttcagatgcaacaaactgaaaatattatccgtagcaaaactccgacaggaccg gagctagattccagctatagaggctatatgaaattgctgggtgagtgcagtggcagtata gactcagtgaagagactggaacacaaactaagggaggaggaagagaattttccaggcttc gttaacctgaatagtacggaaacccaaacagctggtgtgattgaccgatgggaactcatc caagcacaggcccttagcaaggagctgagaatgaaacagaacctccagaagtggcagcag ttcaactcggacctgaacaacatctggacctggctgggggagacagaggaagagttggaa cagctgcagcgcctagagcttagcactgatatccaggctattgagctccagataaaaaag ctcaaggagctccagaaagctgtggaccaccgcaaagccctcatcctctccatcaacctg tgcagctccgagttcacccagactgacagtgaaaaaagccaagatctgcaagatcgccta tcccagatgaacgggcgctgggaccatgtgtgctcattgctagaagagtggcggggcctg ctccaagatgcactgatgcagtgtcaggatttccatgaaatgagtcatggtttgctgctt atgctggagaacatcgacagaaggaaaaatgaaattgtccctattgattctaaccaggat gcagagacacttcaggaccatcacaaacagcttatgcaaataaggcatgagctgttggaa tcccagctcaaagtggcctcactgcaagacatgtcttgccaactcttggtgaatgctgaa ggcacagactgtttagaagccaaagaaaaagtccatgtgattggaaatcggctcaaactt ctcttgaaggaggtcagtcgtcacatcaaggagctggagaagttattagatatgtcaagc agtcagcaggatttgtcttcctggtcttctgctgatgaactggacacctcaggatctgtg agtcctacatcaggaagaagcaccccaaacagacaaagaacgccacgaggcaaatgtagt ctctcacagcctggaccctctgtcaacagtccacatagcaggtccataaaaggtggctcc gattcctccctttctgagcctcggccagctcggtccggccgagccttcctattcagagtc ctccgagcggctcttccacttcagcttctcctgctgcttctcatcgggctcgcctgcctt gtaccaatgtcagaggaagactatagttgtgccctctccaacaactttgcccgatcattc caccccatgctcagatacacaaatggccctcctccgctctga

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