Canis lupus dingo (dingo): 112644815
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Entry
112644815 CDS
T08371
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud01521
EGFR tyrosine kinase inhibitor resistance
clud04062
Chemokine signaling pathway
clud04081
Hormone signaling
clud04148
Efferocytosis
clud04151
PI3K-Akt signaling pathway
clud04217
Necroptosis
clud04550
Signaling pathways regulating pluripotency of stem cells
clud04630
JAK-STAT signaling pathway
clud04658
Th1 and Th2 cell differentiation
clud04659
Th17 cell differentiation
clud04725
Cholinergic synapse
clud04917
Prolactin signaling pathway
clud04920
Adipocytokine signaling pathway
clud04933
AGE-RAGE signaling pathway in diabetic complications
clud04935
Growth hormone synthesis, secretion and action
clud05140
Leishmaniasis
clud05145
Toxoplasmosis
clud05152
Tuberculosis
clud05161
Hepatitis B
clud05164
Influenza A
clud05167
Kaposi sarcoma-associated herpesvirus infection
clud05168
Herpes simplex virus 1 infection
clud05200
Pathways in cancer
clud05207
Chemical carcinogenesis - receptor activation
clud05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
clud05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
112644815 (JAK2)
04151 PI3K-Akt signaling pathway
112644815 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
112644815 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
112644815 (JAK2)
09143 Cell growth and death
04217 Necroptosis
112644815 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
112644815 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
112644815 (JAK2)
04659 Th17 cell differentiation
112644815 (JAK2)
04062 Chemokine signaling pathway
112644815 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
112644815 (JAK2)
04917 Prolactin signaling pathway
112644815 (JAK2)
04935 Growth hormone synthesis, secretion and action
112644815 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
112644815 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112644815 (JAK2)
05207 Chemical carcinogenesis - receptor activation
112644815 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
112644815 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
112644815 (JAK2)
05164 Influenza A
112644815 (JAK2)
05168 Herpes simplex virus 1 infection
112644815 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
112644815 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
112644815 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
112644815 (JAK2)
05140 Leishmaniasis
112644815 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112644815 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
112644815 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112644815 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
clud01001
]
112644815 (JAK2)
Enzymes [BR:
clud01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
112644815 (JAK2)
Protein kinases [BR:
clud01001
]
Non-receptor tyrosine kinases
JAK family [OT]
112644815 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
112644815
NCBI-ProteinID:
XP_025279291
Ensembl:
ENSCAFG00020001020
UniProt:
A0A8C0QV87
LinkDB
All DBs
Position
1:93433078..93551393
Genome browser
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSESPIHQNGDIPGNANSVKQIDPLLQVYLYHSLEKAEEEYLKFPTG
EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTKHNVLYRIRFYF
PYWYCNGSNRTYRHGISRGAEAPLLDDFVMAYLFAQWRHDFLHGWIKIPVTHETQEECLG
MAVLDMMRLAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKRKESETLTEQDLQLYCDFPDIIDVTIKQASQEGSNESRIVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPILMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAIERENVIEYKHCLITKNENGEYNLSGTKKSFRNLKDLLNC
YHMETVRSDSIIFQFTKCCPPKLKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKI
RNEDLMFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINIFWKLEVAKQLAWA
MHFLEEKALIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFPGAFEDQD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaaggaacatccgaatctcctatacat
cagaatggtgatattcctggaaatgctaattctgtgaagcaaatagacccactcctacag
gtgtatctttatcattctcttgagaaagctgaagaagaatatctgaagtttccaactggg
gagtatgttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacacctgtg
tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccac
gtcttccatattgatgaatcaaccaagcacaatgtactctacagaataagattttacttc
ccttactggtattgtaacggcagcaacagaacctatcggcacggaatatctcgaggtgct
gaagctcctcttcttgacgactttgtcatggcttatctttttgctcagtggcggcatgat
tttttacatggatggataaaaatacccgtgactcatgaaacacaggaagaatgtcttgga
atggctgtgctagatatgatgagactagccaaagaaaaggatcaaaccccactggatatc
tatagctctatcagctacaagacattcttacccaaatgtgttcgagcaaagattcaagac
tatcatattttgacaaggaaacgaataaggtacagatttcgcagatttattgagcagttc
agccattgcaaagccactgccagaaacttgaaacttaagtaccttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacgtaaagaaagtgagacactgacagaacaggatttacagttatattgtgacttt
cctgatattattgatgttactattaagcaagcaagccaagaaggctcaaatgaaagtaga
attgtaactatccataagcaagatggtaaaaatctggaaattgaacttagctcattaaga
gaagctttgtcctttgtgtcattaattgatggctattatagattaactgcagatgcacat
cattacctctgtaaagaagtagcacctccaatggtccttgaaaatatacaaagcaactgt
catggcccaattttaatggattttgctatcagtaaactgaagaaagcaggtaatcagact
ggactctatgtacttcgatgcagccctaaggactttaataaatatttcctgacttttgcc
attgagcgagaaaatgtcatcgaatataagcactgtttgattacaaaaaatgaaaatgga
gaatacaacctcagtgggaccaagaagagcttccgtaatcttaaagatcttttgaactgc
taccacatggagactgttcgctcagacagcataattttccagtttaccaaatgctgtccc
ccaaaattgaaagataagtcaaaccttctagtcttcagaaccaatggcgtttctgatgta
ccaacatcaccaacattacagaggcataataatgtgaaccaaatggtgttccacaaaatc
agaaatgaagatttgatgtttaacgaaagtcttggccaaggcacttttacaaaaattttt
aaaggtgtgagaagagaagtaggagactatggtcaactgcatgaaacagaagttctttta
aaagttcttgataaagcacacagaaattattcagagtctttctttgaagcagccagcatg
atgagccagctttctcataagcatctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggaatttgtaaaatttggatcattagatacatatctgaaaaag
aataagaattctataaatatattttggaaacttgaagtggctaaacagttggcatgggca
atgcattttctagaagagaaagcacttattcatggaaatgtgtgtgccaaaaatattctg
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaatttggcgacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcag
agaaagctacagttttatgaagatagacaccaacttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac
atgttaccaaatatgagaattggtgccctagggtttcctggtgcttttgaagaccaagac
cctacacagtttgaagagagacacttgaaatttctacagcaacttggcaagggtaatttt
ggcagtgtggagatgtgccgatatgaccctctacaagacaacactggggaggtggtagct
gtgaagaagctccagcacagtactgaagagcacctgagagactttgagagggaaattgaa
atccttaaatccctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactac
ctccaaaaacataaagaacgaatagatcataaaaaacttctgcagtatacatctcagata
tgcaagggcatggagtatcttggtacaaaaaggtatatacacagggatctggcaacaagg
aatatattggtggagaatgaaaacagggttaaaattggagattttgggttaaccaaagtc
ttgccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctgg
tatgctccagaatcattgacagagagcaagttttctgtggcttcagatgtctggagcttt
ggagtggttctatatgaacttttcacatatattgagaagagtaaaagtccaccagcggaa
tttatgcgtatgattggcaacgacaagcaaggacagatgattgtgtttcatttgatagaa
ctcctaaagaataatggaagattaccaagaccagatggatgcccagatgagatttatttg
atcatgacagaatgctggaataataatgtgaatcagcggccctctttcagagacctagct
cttcgagtggatcagataagggacaacatggctggatga
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integrated database retrieval system
