Canis lupus dingo (dingo): 112645420
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Entry
112645420 CDS
T08371
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud00280
Valine, leucine and isoleucine degradation
clud00640
Propanoate metabolism
clud00785
Lipoic acid metabolism
clud01100
Metabolic pathways
clud01210
2-Oxocarboxylic acid metabolism
Module
clud_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
112645420 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
112645420 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
112645420 (BCKDHA)
Enzymes [BR:
clud01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
112645420 (BCKDHA)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
DUF6409
Motif
Other DBs
NCBI-GeneID:
112645420
NCBI-ProteinID:
XP_025280667
Ensembl:
ENSCAFG00020014768
UniProt:
A0A8C0KL80
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All DBs
Position
1:complement(112693577..112713401)
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AA seq
446 aa
AA seq
DB search
MAVAAAAARVWGSSRGLGQAGLLLLRRPWARGLARSHPQRQEQQHFPSLDDKPQFPGASA
EFIDKLEFIQPNVISGIPVYRVMDRQGQIINPSEDPHLPQEKVLKFYKSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCY
GNVSDPGKGRQMPVHYGCKDRHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEG
AASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYLQSRGWWDDEQEKAWRKQSRKKVMEAFEQAERKPKPNPNLLFSDVYQEMPTQ
LRKQQEALARHLQTYGEHYPLDHFEK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggcggcggcggcagcgagggtctggggctcgagtcgaggtttgggccaggct
ggtctcctgctcctgcgccggccttgggctcgggggctggctagatctcacccccagaga
caggagcagcagcacttcccatccctggatgacaagccccagttcccgggggcctcagcg
gagttcatagacaagctagagttcatccagcccaatgtcatctctgggatccccgtctac
cgcgtcatggaccggcagggccagatcatcaaccccagcgaggatccccacctgccccag
gagaaggtgctcaagttctataagagcatgactctgctcaacaccatggaccgcatcctc
tacgagtcccagcggcagggccggatctccttctacatgaccaactatggcgaggaaggg
acgcatgtggggagtgcagcagccctggacaacacggacctggtgtttggccagtaccgg
gaggcaggtgtgctcatgtacagagactatcccctggagctgttcatggcccagtgctac
ggtaacgtcagcgacccgggcaaggggcgccagatgcccgtgcactatggctgcaaggat
cgccacttcgtcaccatctcctctccattggccacgcagatcccgcaggcggtgggggca
gcctacgcggccaagcgggccaacgccaacagggtggtcatctgctactttggggagggg
gcggccagcgagggggatgcacatgccggcttcaacttcgccgccactctcgagtgcccc
atcatcttcttctgccggaacaacggctatgccatctccacgcccacctcggagcagtac
cgcggggacggcattgctgcccgaggcccgggctatggcatcatgtccatccgtgtggac
ggcaacgacgtgttcgctgtgtacaatgccaccaaggaggcccggcggcgggccgtggca
gagaaccagcccttcctcatcgaggccatgacctacaggatcggtcaccatagcactagt
gacgatagctcagcctaccggtcagtggacgaggtcaattactgggacaagcaggaccac
cccatctcccggctgcgccactatctgcagagtcggggctggtgggatgacgagcaggag
aaggcctggaggaagcagtcccgcaagaaggtgatggaggcctttgagcaggcggagcga
aagccgaagcccaaccccaacttgctcttctcagacgtgtaccaggagatgcccacccag
ctacgcaagcagcaggaggccctggccaggcacctccagacctacggggagcactacccc
ctggaccactttgagaagtga
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