KEGG   Canis lupus dingo (dingo): 112645965
Entry
112645965         CDS       T08371                                 
Symbol
PLD1
Name
(RefSeq) phospholipase D1 isoform X1
  KO
K01115  phospholipase D1/2 [EC:3.1.4.4]
Organism
clud  Canis lupus dingo (dingo)
Pathway
clud00564  Glycerophospholipid metabolism
clud00565  Ether lipid metabolism
clud01100  Metabolic pathways
clud04014  Ras signaling pathway
clud04024  cAMP signaling pathway
clud04071  Sphingolipid signaling pathway
clud04072  Phospholipase D signaling pathway
clud04144  Endocytosis
clud04666  Fc gamma R-mediated phagocytosis
clud04724  Glutamatergic synapse
clud04912  GnRH signaling pathway
clud04928  Parathyroid hormone synthesis, secretion and action
clud05200  Pathways in cancer
clud05208  Chemical carcinogenesis - reactive oxygen species
clud05212  Pancreatic cancer
clud05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:clud00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    112645965 (PLD1)
   00565 Ether lipid metabolism
    112645965 (PLD1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    112645965 (PLD1)
   04072 Phospholipase D signaling pathway
    112645965 (PLD1)
   04071 Sphingolipid signaling pathway
    112645965 (PLD1)
   04024 cAMP signaling pathway
    112645965 (PLD1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    112645965 (PLD1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    112645965 (PLD1)
  09152 Endocrine system
   04912 GnRH signaling pathway
    112645965 (PLD1)
   04928 Parathyroid hormone synthesis, secretion and action
    112645965 (PLD1)
  09156 Nervous system
   04724 Glutamatergic synapse
    112645965 (PLD1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112645965 (PLD1)
   05208 Chemical carcinogenesis - reactive oxygen species
    112645965 (PLD1)
   05231 Choline metabolism in cancer
    112645965 (PLD1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    112645965 (PLD1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:clud04131]
    112645965 (PLD1)
Enzymes [BR:clud01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.4  phospholipase D
     112645965 (PLD1)
Membrane trafficking [BR:clud04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    112645965 (PLD1)
 Endosome - Golgi transport
  Others
   Others
    112645965 (PLD1)
SSDB
Motif
Pfam: PLDc PLDc_2 PX PH zf-C2H2_7th_ZNF462 DUF3785
Other DBs
NCBI-GeneID: 112645965
NCBI-ProteinID: XP_025281378
Ensembl: ENSCAFG00020004212
LinkDB
Position
34:complement(36004926..36209918)
AA seq 1075 aa
MSLKNEPRVNTSALQKIAADMSNLIENLDTRELHFEGEEVDYDVSPSDPKTQEACIPFSA
IYKTQGFKEPNIQTYLSGCPVQAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVKEEPREMPSLPRSSENMIREEQFFGRR
KQLEDYLTKLLKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGLRID
NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAVQENTLAKWYVNAKG
YFEDVANAMEEAEEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFVMLY
KEVELALGINSEYSKRTLMRLHPNIKVMRHPDHVSSSVYLWAHHEKIVVIDQSVAFVGGI
DLAYGRWDDNEHRLTDVGSVKRVTGGPSSLGSFTAETTESMESLSLKNEKESSKNVPTSK
SVDDMDSKLKGIGKSRKFSKFSLYRQLHRHHLHNVDSISSIGSASSYCNHCRSRQNLIHG
LKPHLKLFRSSSKSEQGLPRPDTDTSSLRSLQTGMGELHGETRFWHGKDYCNFVFKDWVQ
LDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFL
LPKSQTTAHELKYQVPGSVHANVQLLRSAADWSAGIKYHEESIHTAYINVIENSKHYIYI
ENQFFISCADDKVVFNKIGDAIAQRILKAHREGQRYRVYVVIPLLPGFEGDISTGGGNAL
QAIMHFNYRTMCRGENSILGQLKAKLGNQWINYISFCGLRTHAELEGNLVTELIYVHSKL
LIADDNTVIIGSANINDRSMLGRRDSEMAVLVQDTETVPSVMDGQAYPAGRFARGLRLQC
FRVVLGYLSDPSENIQDPVSDKFFKEVWVATAARNATIYDKVFRCLPNDEVHNLIQLRDF
ITKPILAREDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAMVPTEVWT
NT seq 3228 nt   +upstreamnt  +downstreamnt
atgtccctgaaaaatgagccaagggtaaacacctctgcactgcagaaaatcgctgcagac
atgagtaacttgatagaaaatctcgacacgcgggagctgcacttcgagggagaagaggtg
gattacgatgtgtctcccagcgatcccaagacacaggaagcgtgtatccctttctctgct
atttataagactcaaggatttaaggagcctaacatacagacgtatctctccgggtgtcca
gtacaagcccaagtcctggaagtggagcgcttcacgtctacgacgagggtaccgagtatc
aatctttacactattgaactaacacatggggaatttaagtggcaagttaagaggaagttc
aaacactttcaagaatttcacagagagctgctcaagtacaaagcttttatccgaatcccc
attcctaccagaagacacacttttagaagacagaatgtcaaagaagagcctcgagagatg
ccaagtttgccccgttcatctgaaaacatgatcagagaagaacaattctttggtagaagg
aaacaactggaagattatttgacaaagttactaaaaatgcccatgtatagaaactaccac
gcgacaacagagttccttgatataagccagctgtctttcatccatgatttgggaccaaag
ggcatagaaggtatgataatgaaaagatccgggggacacaggataccaggcttgaattgc
tgtggtcagggaagagcctgctaccgctggtccaaaaggtggttgatagtgaaagattca
tttttactctatatgaaaccagacagtggtgccattgcctttgtcctgctggtagataaa
gaattcaaaattaaggtcgggaagaaggagactgagacaaaatatggactccgaattgat
aatctttcaaggacacttattttaaaatgcaacagctataggcatgctcggtggtgggga
ggagctatagaggaattcatccagaaacatggcaccaactttctcaaagaccaccgattt
gggtcatatgccgctgtccaagagaatactttagctaaatggtacgttaatgccaaaggg
tattttgaagatgtggcaaatgctatggaagaagcagaagaagagatttttatcacggat
tggtggttgagcccagaaatcttcctgaaacgcccagtggttgaaggaaatcgttggagg
ttggactgcattcttaaacgaaaagcacaacagggagtgagaatctttgtaatgctctac
aaagaggtggaacttgctcttggaatcaacagtgaatacagcaagaggactttgatgcgt
ctacaccccaacataaaggtgatgaggcacccagatcatgtgtcatccagcgtgtatctg
tgggctcatcatgagaaaattgtggtcatcgaccagtcagtggcctttgtgggtgggatc
gacctggcctatggaaggtgggatgataacgaacacagactcacggacgtgggcagtgtg
aagcgtgtcaccggaggaccgtcgtctctgggttctttcacagctgaaacaacggagtcc
atggaatccctaagcctgaaaaatgaaaaggaatctagtaaaaatgtgcccacctcgaag
agtgttgatgatatggattcaaagctgaaaggaataggaaagtccagaaaattctctaaa
tttagcctctacaggcagctccacaggcatcacctgcacaatgtagacagcatcagcagc
attggcagcgcctccagttattgtaatcactgtagaagtcgtcagaatttaatccatggt
ttaaaaccccacctgaaactctttcgctcttccagtaagtctgagcaggggctccctaga
cctgacacggacaccagctccctccgcagtttacagacgggcatgggagagctccatggg
gaaaccaggttctggcatggaaaggactactgcaattttgtcttcaaagactgggtacaa
cttgataaaccttttgctgatttcattgacagatactccactccccggatgccgtggcac
gacattgcctccgcagtccacgggaaggcggctcgcgacgtggcgcgtcacttcatccag
cgctggaacttcacgaagatcatgaaatcaaaatatcggtccctttcatatcctttcctg
cttccaaaatctcaaacaacagcccatgagttgaaatatcaagtgcctgggtccgtccat
gccaatgtacagttgctccgttccgctgctgattggtcggctggtataaagtaccatgaa
gagtccatccacactgcttacatcaacgtgatagagaacagcaaacactatatctatata
gaaaaccagtttttcataagttgtgctgatgacaaagttgtattcaacaagataggtgat
gccattgctcagaggatactgaaagctcacagggaaggccagagataccgggtgtatgtt
gtgataccactgctgccaggatttgaaggagacatttcaaccggtggaggaaatgctctg
caggcaataatgcacttcaactacaggaccatgtgtagaggagaaaattccatccttgga
cagttgaaagccaagcttggcaatcagtggataaattacatatcattctgtggccttaga
acacatgcagagcttgaaggaaacctagtcactgagctcatctatgtccacagcaagttg
ctaattgcggatgacaacactgttattatcggctctgccaacatcaacgaccgcagcatg
ctgggaaggcgcgacagcgaaatggctgtgcttgtgcaggacacggagacggtcccttcg
gtcatggacggacaggcgtaccccgctggccgcttcgcccgaggcctccggctgcagtgc
ttcagggttgtccttggctatctttctgacccaagtgaaaacattcaggatccagtgagt
gacaaattcttcaaggaggtgtgggttgcaacggcagctcgaaatgctacaatatatgat
aaggtgttccggtgccttcccaatgatgaagtacacaatttaattcaattgagagacttt
ataaccaagcccatattagcaagggaagatcccattagagctgaggaagaactgaaaaag
attcgtggcttcttagtgcaattccccttttacttcttgtctgaagaaagcctactgcct
tccgttgggaccaaagaagccatggtgcccacagaggtttggacctaa

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