KEGG   Canis lupus dingo (dingo): 112652877
Entry
112652877         CDS       T08371                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
clud  Canis lupus dingo (dingo)
Pathway
clud04010  MAPK signaling pathway
clud04015  Rap1 signaling pathway
clud04218  Cellular senescence
clud04380  Osteoclast differentiation
clud04620  Toll-like receptor signaling pathway
clud04664  Fc epsilon RI signaling pathway
clud04668  TNF signaling pathway
clud04750  Inflammatory mediator regulation of TRP channels
clud04912  GnRH signaling pathway
clud04935  Growth hormone synthesis, secretion and action
clud04936  Alcoholic liver disease
clud05014  Amyotrophic lateral sclerosis
clud05022  Pathways of neurodegeneration - multiple diseases
clud05132  Salmonella infection
clud05135  Yersinia infection
clud05145  Toxoplasmosis
clud05161  Hepatitis B
clud05163  Human cytomegalovirus infection
clud05167  Kaposi sarcoma-associated herpesvirus infection
clud05169  Epstein-Barr virus infection
clud05170  Human immunodeficiency virus 1 infection
clud05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
clud05417  Lipid and atherosclerosis
clud05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:clud00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112652877 (MAP2K6)
   04015 Rap1 signaling pathway
    112652877 (MAP2K6)
   04668 TNF signaling pathway
    112652877 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    112652877 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    112652877 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    112652877 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    112652877 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    112652877 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112652877 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112652877 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112652877 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112652877 (MAP2K6)
   05161 Hepatitis B
    112652877 (MAP2K6)
   05163 Human cytomegalovirus infection
    112652877 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112652877 (MAP2K6)
   05169 Epstein-Barr virus infection
    112652877 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112652877 (MAP2K6)
   05135 Yersinia infection
    112652877 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    112652877 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    112652877 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    112652877 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112652877 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    112652877 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    112652877 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:clud01001]
    112652877 (MAP2K6)
Enzymes [BR:clud01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     112652877 (MAP2K6)
Protein kinases [BR:clud01001]
 Serine/threonine kinases: STE group
  STE7 family
   112652877 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 112652877
NCBI-ProteinID: XP_025292278
Ensembl: ENSCAFG00020020176
LinkDB
Position
9:complement(10619229..10740716)
AA seq 334 aa
MSQSKGRKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCLFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaggaagcggaaccctggtcttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacgccccctcgagacttagactctaaagcttgcatttca
attggaaatcagaactttgaggtgaaggcagatgacctggagcctataatggaactgggg
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtctttttacggtcaccttttatggcgcactcttc
cgggagggtgatgtttggatctgcatggagctcatggatacgtcgctagataagttctac
aaacaagtgattgataaaggccaaacgattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcgttagaacacttacacagtaagctctctgtcattcatcgagatgtc
aagccttccaacgtgctgatcaacgctctgggccaagtaaagatgtgcgattttggaatc
agtggctaccttgtagactctgtcgctaaaactattgatgcaggatgcaaaccgtacatg
gcccctgaaagaataaacccagagctcaatcagaagggatatagtgtgaagtctgacatt
tggagtctgggcatcacaatgattgagttggctatcctccggtttccctatgactcttgg
ggaactcccttccagcagctcaaacaggtggtagaggaaccctcgccacagctcccggcg
gacaaattctctgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccaacatatccagaacttatgcaacatccgtttttcaccctacacgaatccaaa
gcaacagacgtggcatcttttgtaaaactaattcttggagactaa

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