Canis lupus dingo (dingo): 112653816
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Entry
112653816 CDS
T08371
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud01521
EGFR tyrosine kinase inhibitor resistance
clud01522
Endocrine resistance
clud04010
MAPK signaling pathway
clud04014
Ras signaling pathway
clud04015
Rap1 signaling pathway
clud04066
HIF-1 signaling pathway
clud04068
FoxO signaling pathway
clud04081
Hormone signaling
clud04114
Oocyte meiosis
clud04140
Autophagy - animal
clud04144
Endocytosis
clud04150
mTOR signaling pathway
clud04151
PI3K-Akt signaling pathway
clud04152
AMPK signaling pathway
clud04211
Longevity regulating pathway
clud04213
Longevity regulating pathway - multiple species
clud04510
Focal adhesion
clud04520
Adherens junction
clud04550
Signaling pathways regulating pluripotency of stem cells
clud04730
Long-term depression
clud04913
Ovarian steroidogenesis
clud04914
Progesterone-mediated oocyte maturation
clud05200
Pathways in cancer
clud05202
Transcriptional misregulation in cancer
clud05205
Proteoglycans in cancer
clud05214
Glioma
clud05215
Prostate cancer
clud05218
Melanoma
clud05224
Breast cancer
clud05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112653816 (IGF1R)
04014 Ras signaling pathway
112653816 (IGF1R)
04015 Rap1 signaling pathway
112653816 (IGF1R)
04066 HIF-1 signaling pathway
112653816 (IGF1R)
04068 FoxO signaling pathway
112653816 (IGF1R)
04151 PI3K-Akt signaling pathway
112653816 (IGF1R)
04152 AMPK signaling pathway
112653816 (IGF1R)
04150 mTOR signaling pathway
112653816 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
112653816 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
112653816 (IGF1R)
04140 Autophagy - animal
112653816 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
112653816 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
112653816 (IGF1R)
04520 Adherens junction
112653816 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
112653816 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
112653816 (IGF1R)
04914 Progesterone-mediated oocyte maturation
112653816 (IGF1R)
09156 Nervous system
04730 Long-term depression
112653816 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
112653816 (IGF1R)
04213 Longevity regulating pathway - multiple species
112653816 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112653816 (IGF1R)
05202 Transcriptional misregulation in cancer
112653816 (IGF1R)
05205 Proteoglycans in cancer
112653816 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112653816 (IGF1R)
05214 Glioma
112653816 (IGF1R)
05218 Melanoma
112653816 (IGF1R)
05215 Prostate cancer
112653816 (IGF1R)
05224 Breast cancer
112653816 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112653816 (IGF1R)
01522 Endocrine resistance
112653816 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
clud01001
]
112653816 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
clud04090
]
112653816 (IGF1R)
Enzymes [BR:
clud01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
112653816 (IGF1R)
Protein kinases [BR:
clud01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
112653816 (IGF1R)
CD molecules [BR:
clud04090
]
Proteins
112653816 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
112653816
NCBI-ProteinID:
XP_025293857
Ensembl:
ENSCAFG00020019842
UniProt:
A0A8C0L611
LinkDB
All DBs
Position
3:41768801..42071720
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNTTVVDTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
RRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRL
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcgtgtttctctcc
gccgcgctgtcgctctggccgacgagtggagaaatctgtgggccaggcatcgacatccgc
aatgactatcagcagctgaagcgcctggagaactgtacagtgatcgagggctacctccac
atcctactcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgtgtggccggccttgagagcctcggggatctcttc
cccaacctcacagtcatccgcggctggaagctcttctacaactacgccctggtcatcttt
gagatgaccaacctcaaggatattgggctttacaatctgaggaacattactcggggggcc
atcaggattgagaagaatgctgacctctgttacctctccacagtggactggtccctgatc
ctggatgcagtgtccaacaactacatcgtggggaacaaaccccctaaggaatgtggggac
ctgtgtccagggacaatggaggagaagcccttgtgtgagaagactaccatcaacaatgaa
tacaactatcgctgctggactacaaatcgctgccagaaaatgtgcccgagcgcttgcggg
aagcgggcgtgcacggagaacaacgagtgttgtcaccccgagtgtctgggcagctgcagc
gcgccggacaacgatacggcctgtgtggcctgcaggcattactactacgcaggcgtctgc
gtgcccacctgcccgcccaacacctaccgctttgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccatgac
ggcgagtgcatgcaggagtgcccctctgggttcatccgcaatggcagtcagagcatgtac
tgcatcccttgtgaaggtccttgtcccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgtaccatcttcaagggcaatttg
ctcattaatatccgccgaggcaataacattgcctcagagctggagaacttcatggggctc
atcgaggtggtgacaggctacgtgaagatccgccattcccatgccttggtctccctgtcc
ttcctaaaaaaccttcgccagatcttaggagaggaacagctggaggggaactactccttc
tacgtcctcgacaaccagaacttgcagcagctttgggattgggaccaccgtaacctgacc
atcaaagctgggaaaatgtattttgctttcaatcccaaattgtgcgtctccgaaatttac
cgcatggaagaagtgacggggaccaaaggacgccagagcaaaggagacataaataccaga
aacaatggagagcgagcctcctgtgaaagcgacgtcctgcacttcacctctacgaccaca
tggaagaatcgcatcatcatcacgtggcaccgttaccggccccctgactacagggacctc
atcagctttactgtctactacaaggaagcaccttttaaaaacgttacggagtatgatggg
caggatgcctgtggctccaacagctggaatatggtagatgtggacctccctcccaacaag
gacgttgagcctggcattttactgcacggactgaagccctggacgcagtatgcggtttat
gtcaaggcggtgaccctcaccatggtggagaatgaccacatccgtggggctaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctttctgca
tcaaactcctcttctcagctcattgtgaagtggaacccaccctctctgcccaacggtaac
ctcagttactacatcgtgaggtggcagcggcagccccaggacagttacctttaccgccac
aactactgctccaaagataaaatccccatcaggaagtatgctgatggcactattgatgtc
gaagaggtgacagagaatcccaagaccgaagtatgtggtggagagaaggggccttgctgt
gcctgccccaaaactgaggccgagaagcaggctgagaaggaggaggccgagtaccgcaaa
gtgttcgagaatttcctgcacaactccatcttcgtgcccagacctgaaaggaagcgtaga
gatgttacacaagtcaccaacaccaccatgtccagccgaagcaggaacaccacggtggtg
gacacctataatatcacagacccagaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtaatctctaacctccggccttttaccctgtaccgc
attgacatccacagctgtaatcatgaggctgagaagctgggctgcagtgcctccaacttt
gtttttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccagtgacctgg
gagtcaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatatggatcccaaatcgaggatcagcgggaatgtgta
tccagacaggagtacaggaagtatggaggtgccaagcttaaccggctcaacccggggaac
tatacagcccggatccaggccacttctctctctgggaatgggtcgtggacggatcctgtg
ttcttctatgtcccagccaaaataacgtatgaaaacttcatccatctgatcattgctctg
cccgttgctgtgctattgatagtgggagggttggttataatgctgtacgtcttccacagg
agaagaaataacagcaggctggggaatggagtgctgtatgcttccgtgaacccagaatac
ttcagtgctgccgatgtgtatgtacctgatgagtgggaggttgctcgagagaagatcacc
atgagccgagagctgggccagggctcgtttgggatggtatatgaaggagttgccaagggt
gtggttaaagatgagcctgaaacaagggtggccattaaaacagtgaacgaggccgccagc
atgcgtgaaaggatcgaatttctcaatgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggtgtggtgtcccagggccagccgacgctggtcatcatggaa
ctgatgacacgaggggatctcaaaagttatctcaggtctctgaggccagaaatagagaat
aatccagtcctcgcacctccaagcctaagcaagatgatccagatggctggggagattgct
gatggcatggcatacctcaatgccaacaagtttgtccacagagaccttgctgccaggaac
tgcatggtggccgaagatttcacagtcaaaattggagatttcggtatgacaagagacatc
tatgagacagactattaccggaaaggaggcaaggggctgctgcctgtgcgctggatgtca
cctgagtctctcaaggatggagtcttcaccactcactctgacgtctggtcctttggggtc
gttctctgggagatcgccacgctggctgagcagccataccagggcttgtccaacgagcaa
gtccttcgcttcgttatggagggcggccttctggacaagccggacaactgccccgacatg
ctgtttgagctgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggacctggagccggagaacatg
gagagtgtccccctggacccgtcggcctcctcgtcgtccctgcctctgcctgacagactc
tcaggacacaaggccgagaacggcccaggccctggcgtgctggtcctgcgagccagcttc
gatgagagacagccttacgcgcacatgaacgggggccgcaagaacgagcgggccttgcct
ctgccccagtcttcgacctgctga
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integrated database retrieval system
