Canis lupus dingo (dingo): 112656405
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Entry
112656405 CDS
T08371
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud00230
Purine metabolism
clud00670
One carbon pool by folate
clud01100
Metabolic pathways
clud01523
Antifolate resistance
Module
clud_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112656405 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
112656405 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112656405 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
clud04147
]
112656405 (ATIC)
Enzymes [BR:
clud01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
112656405 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
112656405 (ATIC)
Exosome [BR:
clud04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
112656405 (ATIC)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
112656405
NCBI-ProteinID:
XP_025297510
Ensembl:
ENSCAFG00020027231
UniProt:
A0A8C0LS58
LinkDB
All DBs
Position
37:22817913..22844031
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AA seq
592 aa
AA seq
DB search
MAPGQLALFSVSDKTGLVEFARSLTSVGLSLLASGGTATALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFSLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVAVSTEMQSSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALDIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
TAYARARGADRMSSFGDFIALSDICDVPTAKIISREVSDGIVAPGYEDEALKILSKKKNG
NYCVLQMDQSYNPDENEVRTLFGLRLSQKRNNGVIDRSLFSNIVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANCWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTETEKKEWVDKLSEVSISSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcgcccggccagctcgccctgttcagcgtctctgacaaaacgggcctggtggaattt
gccagaagcctcacgtctgtgggtctgagcctcctcgcctccggagggaccgcgacagct
ctccgggatgccgggctggcggtcagagatgtctctgagctcacaggatttcctgaaatg
ttagggggacgtgtgaaaaccttgcatcctgcagtccatgctggaatcttggctcgtaat
atcccagaagataatgctgacatggccagacttgattttagtcttataagagttgtcgtt
tgtaatctgtatccctttgtgaagactgtggcttctccagatgtaactgttgaacaggct
gttgagcagattgatattggtggagtaaccctattgagagcagcggccaaaaaccatgct
cgagtgacagtagtatgtgaacccgaggactatgtggccgtgtccacagagatgcagagc
tctgacagtaaagacacctccttggagaccagacgccagttagccttgaaggctttcact
catacggcacaatatgatgaagcaatttcagattacttcaggagacagtatagcaaagga
atatctcaaatgcccttgaggtatggaatgaaccctcatcaaactcctgcccagttatac
acactgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttg
tgcgatgctttgaatgcctggcagctggtgaaggaactcaaagaagctttagacattcca
gccgctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactcagt
gaagatgaggccaaagtctgcatggtctatgatctgtataaaacccttacacccatatca
actgcatatgcaagagcaagaggggctgataggatgtcctcatttggtgactttatcgca
ttatctgatatctgtgatgtccctactgccaaaattatctccagagaggtatctgatggt
attgttgccccaggctatgaagatgaagctttgaaaatactttctaaaaagaaaaatggg
aactactgtgttcttcagatggatcagtcttacaatccagatgaaaacgaagttcgaact
ctctttggtcttcgtttaagtcagaagagaaataatggtgtcattgacaggtcattattt
agcaacattgtgaccaagaataaagatttgccagagtctgcactcagagacctcattgta
gccaccattgctgtgaagtacacgcagtctaactccgtgtgctatgccaagaatggccag
gttattggcattggagcaggacagcaatctcgaattcactgcacacgccttgcaggggat
aaggcaaactgttggtggcttagacatcatccacaagtgctttcaatgaagtttaaaact
ggagtgaagagagcagaaatctccaatgccattgatcagtatgttactggaacgattggc
gaggatgaagacttgataaagtggaaggcattgtttgaggaagtccctgaattattaact
gaaacagagaagaaggaatgggtggacaaacttagtgaagtttctatcagctctgacgcc
ttctttcctttcagggataatgtagacagagctaaaaggagtggtgtggcctacattgct
gctccttctggttctgctgctgacaaagttgtgattgaggcttgcgatgaactgggaata
atccttgctcatacaaaccttcggctctttcatcactga
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