Canis lupus dingo (dingo): 112657995
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Entry
112657995 CDS
T08371
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud01521
EGFR tyrosine kinase inhibitor resistance
clud01522
Endocrine resistance
clud04010
MAPK signaling pathway
clud04012
ErbB signaling pathway
clud04014
Ras signaling pathway
clud04062
Chemokine signaling pathway
clud04068
FoxO signaling pathway
clud04072
Phospholipase D signaling pathway
clud04150
mTOR signaling pathway
clud04151
PI3K-Akt signaling pathway
clud04510
Focal adhesion
clud04540
Gap junction
clud04630
JAK-STAT signaling pathway
clud04650
Natural killer cell mediated cytotoxicity
clud04660
T cell receptor signaling pathway
clud04662
B cell receptor signaling pathway
clud04664
Fc epsilon RI signaling pathway
clud04714
Thermogenesis
clud04722
Neurotrophin signaling pathway
clud04810
Regulation of actin cytoskeleton
clud04910
Insulin signaling pathway
clud04912
GnRH signaling pathway
clud04915
Estrogen signaling pathway
clud04917
Prolactin signaling pathway
clud04926
Relaxin signaling pathway
clud04935
Growth hormone synthesis, secretion and action
clud05034
Alcoholism
clud05160
Hepatitis C
clud05161
Hepatitis B
clud05163
Human cytomegalovirus infection
clud05165
Human papillomavirus infection
clud05200
Pathways in cancer
clud05205
Proteoglycans in cancer
clud05206
MicroRNAs in cancer
clud05207
Chemical carcinogenesis - receptor activation
clud05208
Chemical carcinogenesis - reactive oxygen species
clud05210
Colorectal cancer
clud05211
Renal cell carcinoma
clud05213
Endometrial cancer
clud05214
Glioma
clud05215
Prostate cancer
clud05220
Chronic myeloid leukemia
clud05221
Acute myeloid leukemia
clud05223
Non-small cell lung cancer
clud05224
Breast cancer
clud05225
Hepatocellular carcinoma
clud05226
Gastric cancer
clud05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112657995 (SOS2)
04012 ErbB signaling pathway
112657995 (SOS2)
04014 Ras signaling pathway
112657995 (SOS2)
04630 JAK-STAT signaling pathway
112657995 (SOS2)
04068 FoxO signaling pathway
112657995 (SOS2)
04072 Phospholipase D signaling pathway
112657995 (SOS2)
04151 PI3K-Akt signaling pathway
112657995 (SOS2)
04150 mTOR signaling pathway
112657995 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
112657995 (SOS2)
04540 Gap junction
112657995 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
112657995 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
112657995 (SOS2)
04660 T cell receptor signaling pathway
112657995 (SOS2)
04662 B cell receptor signaling pathway
112657995 (SOS2)
04664 Fc epsilon RI signaling pathway
112657995 (SOS2)
04062 Chemokine signaling pathway
112657995 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
112657995 (SOS2)
04912 GnRH signaling pathway
112657995 (SOS2)
04915 Estrogen signaling pathway
112657995 (SOS2)
04917 Prolactin signaling pathway
112657995 (SOS2)
04926 Relaxin signaling pathway
112657995 (SOS2)
04935 Growth hormone synthesis, secretion and action
112657995 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
112657995 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
112657995 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112657995 (SOS2)
05206 MicroRNAs in cancer
112657995 (SOS2)
05205 Proteoglycans in cancer
112657995 (SOS2)
05207 Chemical carcinogenesis - receptor activation
112657995 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
112657995 (SOS2)
05231 Choline metabolism in cancer
112657995 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
112657995 (SOS2)
05225 Hepatocellular carcinoma
112657995 (SOS2)
05226 Gastric cancer
112657995 (SOS2)
05214 Glioma
112657995 (SOS2)
05221 Acute myeloid leukemia
112657995 (SOS2)
05220 Chronic myeloid leukemia
112657995 (SOS2)
05211 Renal cell carcinoma
112657995 (SOS2)
05215 Prostate cancer
112657995 (SOS2)
05213 Endometrial cancer
112657995 (SOS2)
05224 Breast cancer
112657995 (SOS2)
05223 Non-small cell lung cancer
112657995 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
112657995 (SOS2)
05160 Hepatitis C
112657995 (SOS2)
05163 Human cytomegalovirus infection
112657995 (SOS2)
05165 Human papillomavirus infection
112657995 (SOS2)
09165 Substance dependence
05034 Alcoholism
112657995 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112657995 (SOS2)
01522 Endocrine resistance
112657995 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
IQ_SEC7_PH
PH_13
Motif
Other DBs
NCBI-GeneID:
112657995
NCBI-ProteinID:
XP_025299903
Ensembl:
ENSCAFG00020021773
UniProt:
A0A8C0L891
LinkDB
All DBs
Position
8:complement(26706036..26786427)
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQLYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVCLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRNLFKPSDI
DRIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSNAEYRLKEKFIMRKTQICDKEDTCECKHAFELISKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPMPLEREPYKISFSRIAETDLESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNTKSDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCYLLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPSY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagctgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgctggtctcggccctgcggaaggttcaggagcaagtacatcctaatctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggctcaaccaaggactgttcaagatgtggaggaacgtgttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacaatctgccatagaaaaacgaaaacgaaga
aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactatcatgtatccctgtatattgtggctgtactagagtatatctcagctgat
attttgaagttggctggtaattatgtttttaatatccgacattatgaaatatctcagcag
gacattaaagtatcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttgtctttgtgaagatgaacctagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaaggcaatatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcctttctttcggacagaaatctgtttaaaccttctgatatt
gacagaattttcagtaacatttcagatatacacgaattgactgtgaaacttctaggtttg
attgaagacacagtggaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaggagcaagcatttgatccttatgaaacattatcacaggacatt
ctttctccaaaatttaatgaacatttcagtaagctgatggccagacctgcagtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctagtgcctgtttatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcaggaagacagagaatgtttgaaccaagctattacagctcttatgaat
ctccagggtagcatggaccgaatttataagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcatctagctattaaaaaaatg
aatgaaattcagaaaaacatagatgggtgggaaggcaaagatattggacagtgttgtaat
gaattcattatggaaggtccattgacacgaattggtgctaaacatgaacgacatattttt
ctctttgatggcttaatgattagctgtaagcccaatcatagccagtcacgccttccaggt
tacagtaatgcagaatacagattaaaagaaaaatttatcatgaggaagacacagatatgt
gataaagaagatacttgtgagtgcaaacacgcttttgagttgatatccaaagatgaaaac
agcataatatttgctgctaaatcggctgaagagaaaaataattggatggccgcacttatt
tctcttcactatcgtagtacactagatcgaatgctagattcagtgttattgaaagaagaa
aatgagcaaccattgagattaccaagtcctgaagtatatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaattcccattattaaa
ggaggaactgtggtgaaattaattgaaagattaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacataccgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaatcccagagccggaacctactgaagcagataaattggct
gtagagaaaggcgaacagccaatcagtgcagaccttaaaaggtttcgcaaggaatatgtc
caaccagtacaacttaggatcttaaatgtatttcggcactgggttgaacaccacttttat
gactttgaaagggatttggagttgcttgaaagactagaatccttcatttcaagtgtaaga
ggaaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccaccaattgaa
tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacactgcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagtccaaccttct
gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacgaatctcaccctttggtttgaaaagtgcattgtggaagca
gaaaattttgaagaacgggtggcaatactaagcagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtatca
gtgtacagactagaccatacttttgaggcattgcaggaaagaaaaaggagaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaaaactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggagattctttgaaaaccttaaccccatgggaaatgcttctgaa
aaggagtttacagattatttgttcaacaagtcactagaaattgagccccgaaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaatacggccg
aatacaggccgacatggctctacctcaggcactttacgaggtcatccaatgccgttagaa
agagaaccatataaaataagctttagtcggattgctgaaactgatcttgaatcaactgtg
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggcagcaatagcatctttgctcca
gtcctcttgccgcattcaaagtctttcttcagttcatgtggtagtttacataaactaagt
gaagagccactgattcctcctcctcttcctcctcgaaaaaagtttgatcatgatgcttca
aattccaagggaaatacgaaatctgatgatgacccccctgctattccaccaagacaacct
cctcctccaaaggtaaaacctagagttcctgctcctactggtgcatttgatgggcctctg
catagtccacctccaccgccaccaagagatcctcttcctgatacccctccgccagttccc
cttcgtcctccagaacactttataaactgtccatttaatcttcagccacctccactagga
catctgcacagagatccagactggttcagagacgttagtacctgcccaaattcgccaaat
actcctcccagcacgccctctccaagagtaccacgtcgatgctacctgctcagttctagt
cacaacaaccttgctcatcctcaagctccccctgtgccaccgaggcagaactcaagcccg
cacctaccaaaactgccaccaaagacttataaacgggagctttcacaccccccgtcatac
agactgcctttactagaaaatgcagaaactcctcaatga
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